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    What is the Anti Nuclear Antibody (ANA) (IFA) Test?

    The ANA test, or Anti-nuclear Antibody test, measures the concentration and pattern of antinuclear antibodies in your blood. These antibodies typically defend the body against harmful invaders like bacteria and viruses. However, in autoimmune diseases, these antibodies may attack healthy cells, targeting the nucleus—the cell's central part—hence the name antinuclear antibodies.

    This test is crucial for diagnosing autoimmune diseases like systemic lupus erythematosus (SLE) and rheumatoid arthritis. Doctors rely on ANA test results alongside other lab findings, clinical symptoms, and physical examinations to confirm a diagnosis. By compiling this information, doctors can ascertain if the immune system is wrongly attacking the body and choose the best treatment plan.

    If you're in Noida and experiencing joint pain, chronic fatigue, or persistent rashes, consider getting an ANA test. Early detection of autoimmune disorders through this test can help you start the necessary treatments promptly.

    Anti Nuclear Antibody (ANA) (IFA) Test Parameters

    The ANA IFA test focuses on two main aspects: titre value and fluorescent pattern.

    Pattern: The test also assesses how these antibodies interact with different cell parts using a fluorescent dye, which glows under a microscope. This pattern helps in identifying specific autoimmune diseases like lupus, rheumatoid arthritis, or Sjögren’s syndrome. By examining these patterns, doctors can determine if additional tests are required to identify specific antibodies.

    Titre Value: This measures the amount of antinuclear antibodies (ANAs) in your blood. To find this, the blood is diluted step-by-step until no antibodies are visible. The highest dilution level where antibodies are still detectable is recorded as the titre. A higher titre indicates more antibodies and a greater risk of autoimmune disease.

    The ANA test uses the Indirect Immunofluorescence (IFA) method, which allows the visualisation of these patterns and offers vital clues in diagnosing autoimmune conditions.

    Anti Nuclear Antibody (ANA) (IFA) Test Preparation

    Before undergoing an ANA test at home, take note of the following:

    • Prerequisites

    Fasting is not necessary before the ANA test.

    • Best Time to Get Tested

    The ANA test can be carried out at any time of day.

    • Who Should Get an ANA Profile Test?

    An ANA test is advised if your doctor suspects an autoimmune disease. It is usually recommended if you experience symptoms like fever, noticeable skin changes or rashes, joint or muscle pain, stiffness, swelling, or extreme fatigue. The test identifies specific antibodies in your blood, aiding doctors in diagnosing autoimmune disorders.

    • Cautions Before Taking the ANA Profile Test

    There are no specific preparations or cautions typically needed for getting an ANA test at home.

    Why Take the Anti Nuclear Antibody (ANA) (IFA) Test?

    The ANA test identifies specific antibodies in your blood, helping doctors diagnose autoimmune conditions such as:

    • Systemic Lupus Erythematosus (SLE): Affects the skin, joints, and various organs.

    • Autoimmune Hepatitis: This leads to inflammation in the liver.

    • Rheumatoid Arthritis: Primarily targets joints, causing pain and swelling.

    • Sjögren's Syndrome: Impairs glands that produce tears and saliva.

    • Addison Disease: A disorder of the adrenal glands, characterized by weakness and fatigue.

    • Scleroderma: A rare condition affecting the skin and internal organs.

    This test is often suggested if you have symptoms like joint pain, fever, persistent fatigue, rashes, or muscle pain to determine if an autoimmune disease is present.

    Anti Nuclear Antibody (ANA) (IFA) Test Results & Interpretation

    The ANA test identifies antinuclear antibodies, which can help detect autoimmune diseases by targeting the cell nucleus.

    • Negative Results: Suggest no antibodies are present, making an autoimmune disorder less likely, though not impossible.

    • Positive Results: Indicates that these antibodies exist, which may point to an autoimmune disease, viral infection, or other health conditions.

    • Weakly Positive Results: For weakly positive results, retesting in 6-8 weeks is recommended for a more accurate assessment.

    Positive ANA results can be further interpreted based on the observed patterns:

    • Centromere Pattern: Related to specific types of scleroderma, affecting proteins involved in cell division.

    • Cytoplasmic Patterns: May be linked to liver disease, Sjögren's syndrome, and muscle disorders.

    • Homogeneous Pattern: Typically associated with lupus, indicating antibodies against DNA and histones.

    • Speckled Pattern: Linked to conditions like lupus, Sjögren's syndrome, or rheumatoid arthritis, involving various nuclear proteins.

    • Dense Fine Speckled (DFS): Sometimes seen in healthy people and inflammatory conditions.

    • Nuclear Dot Pattern: Associated with liver disease and certain rheumatic conditions, involving specific nuclear proteins.

    • Nuclear Membrane Pattern: Seen in chronic fatigue syndrome and collagen-related diseases.

    • Nucleolus Pattern: Suggestive of disorders affecting muscles and skin.

    A positive ANA test alone does not confirm an autoimmune disease diagnosis. Further diagnostic tests and clinical evaluation are needed to identify the exact disease.

    FAQs on Anti Nuclear Antibody (ANA) (IFA) Test in Noida

    The ANA test costs ₹ 1300 in Noida, which includes the fastest home sample collection within 60 minutes of booking. The results will be ready in 120 hours.

    Yes, Orange Health Labs offers a home collection for ANA tests in Noida. Your sample can be collected from home within 60 minutes after you book, based on slot availability.

    The ANA test helps detect antibodies that attack the cell nucleus, assisting in diagnosing autoimmune disorders such as lupus and rheumatoid arthritis. A positive outcome may point to an autoimmune disease.

    Fasting is not needed for the ANA Profile test.

    Here’s how you can book an ANA Profile test with Orange Health Labs:

    • Locate the Test: Use our platform to search for the Antinuclear Antibody/ANA test available in Noida or for home collection, and visit the Orange Health page.

    • Check and Confirm Details: Select the test, review the necessary prerequisites, enter your location, and complete the booking by picking a suitable time for sample collection.

    • Sample Collection: A trained eMedic will arrive at your home at the scheduled time to collect the sample.

    • Lab Processing: Your sample will then be sent to our ICMR-approved and NABL-accredited lab for analysis.

    • Results NOAivery: You’ll receive your results through email or WhatsApp within 120 hours, and they can also be accessed via our app.

    The results of the ANA test can be either negative or positive. A negative result suggests a low probability of having an autoimmune disorder, whereas a positive result indicates the presence of antibodies, which may be associated with autoimmune conditions. High antibody levels could point to more active disease, necessitating further testing.

    Once you book an ANA test with Orange Health Labs, a technician will collect your sample within around 60 minutes. The collection process itself is quick, and you should receive your results online within 120 hours.

    The need for repeat ANA testing will be determined by your healthcare provider based on your health status and symptoms.

    The ANA test evaluates both the antibody titre and the specific patterns present. A lower titre implies a lesser likelihood of autoimmune disease, while a higher titre suggests greater disease activity. Patterns like homogeneous and speckled are used to diagnose diseases such as lupus and rheumatoid arthritis.

    Orange Health offers ANA testing services across various areas in Noida, with the option of convenient home sample collection such as DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, DLF Phase 5, Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56..

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    References

    1. Medline Plus. ANA (Antinuclear Antibody) Test: MedlinePlus Medical Test [Internet]  Available from:  https://medlineplus.gov/lab-tests/ana-antinuclear-antibody-test/
    2. Antinuclear Antibodies (ANA) Test [Internet].  Available from:  https://www.columbiadoctors.org/health-library/test/antinuclear-antibodies-ana-test/
    3. Fastest Anti-nuclear Antibody (ANA) (IFA) Test in Noida at Best Price + Reports in 6 Hours [Internet].  Available from:  https://www.orangehealth.in/lab-test-bangalore/anti-nuclear-antibody?utm_source=seo_search&utm_medium=google&utm_campaign=seo&utm_term=anti-nuclear-antibody