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    Cancer Antigen 125 (CA 125)2400160033% off
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    What Is Cancer Antigen 125 (CA 125) Test?

    The CA-125 test measures the level of a specific protein, Cancer Antigen 125, in the blood. This protein can act as a tumour marker and is often elevated in cases of ovarian cancer. The ovaries, which are female reproductive organs responsible for storing and releasing eggs and producing hormones, are one source of CA-125. It is also produced by the lining cells of other organs, such as the fallopian tubes and uterus. Elevated CA-125 levels can be found in a variety of cancers and other health conditions. This test is particularly useful for screening postmenopausal women who are at an increased risk of ovarian cancer due to family history or genetic predisposition. Additionally, it is used to evaluate individuals with symptoms that could suggest ovarian cancer. The CA-125 test is especially valuable for monitoring the progress of ovarian cancer treatment and detecting any recurrence after treatment.

    If you reside in Mumbai and have risk factors or symptoms suggestive of ovarian cancer, your doctor may recommend a CA-125 test, which can be conveniently performed at home to monitor your health or assess your risk.

    Cancer Antigen 125 (CA 125) Test Parameters

    The CA-125 test has only one parameter: to measure the concentration of the CA-125 protein in the blood.

    This protein is a tumour marker produced by ovarian cancer cells and the cells lining various organs, including the endometrium, fallopian tubes, lungs (pleura), gut (peritoneum), and heart (pericardium). It is widely used in serological tests when ovarian cancer is suspected and for monitoring individuals diagnosed with epithelial ovarian cancers. CA-125 is considered to suppress the immune system's ability to destroy diseased cells, such as those that are infected or cancerous.

    Normally, CA-125 remains on the surface of cells, as protective barriers prevent it from entering the bloodstream. However, when these barriers are breached by cancerous cells, CA-125 leaks into the blood, leading to elevated levels that can be detected by the test. Additionally, CA-125 may interact with other proteins within cells, promoting cancer growth and metastasis.

    Elevated levels of CA-125 are most commonly associated with ovarian cancer, particularly epithelial ovarian cancer, but may also occur in other cancers, such as those of the uterus, breast, and fallopian tubes. Non-cancerous conditions like ovarian cysts, fibroids, and endometriosis, as well as normal physiological states like early pregnancy, the postpartum period, and menstruation, can also result in increased CA-125 levels.

    Cancer Antigen 125 (CA 125) Test Preparation

    Here is how to prepare for a Cancer Antigen 125 test at home:

    Pre-requisites

    Fasting is not necessary before taking the CA-125 test.

    Best Time to Get Tested

    The CA-125 test can be conducted at any time during the day.

    Who Should Get a Cancer Antigen 125 (CA-125) Test

    This test is recommended for diagnosing ovarian cancer in women with symptoms or risk factors such as a family history or genetic predisposition. It is also useful for monitoring women who have already been diagnosed with ovarian cancer and are receiving treatment. After treatment, the test can be performed regularly to check for cancer recurrence.

    Cautions Before Taking a Cancer Antigen 125 (CA-125) Test

    Keep in mind that elevated CA-125 levels can occur in non-cancerous conditions like pregnancy, menstruation, and fibroids. Consult your doctor about any precautions you should take before the test.

    Why Take the Cancer Antigen 125 (CA 125) Test?

    A CA-125 test is a valuable tool in ovarian cancer management and risk assessment. Here’s why you might need this test:

    • Evaluating Pelvic Lumps : When a suspicious lump is detected in the pelvic area through imaging tests, such as ultrasound, CA-125 levels can help determine if the lump might be ovarian cancer.

    • High-Risk Assessment

      • Individuals with a family history of ovarian, breast, or colorectal cancer.

      • Those with genetic mutations, such as BRCA1 or BRCA2.

      • Individuals with hereditary conditions like Lynch syndrome that increase cancer risk.

      • Anyone with a history of ovarian, breast, colorectal, or uterine cancer.

    • Monitoring Treatment : If you’ve been diagnosed with ovarian cancer, CA-125 tests are performed regularly during treatment to track its effectiveness. A drop in CA-125 levels generally suggests that the treatment is working.

    • Checking for Recurrence : After cancer treatment, CA-125 levels might be checked periodically, whether every few months or annually, to see if the cancer has returned.

    Given that elevated CA-125 levels can be found in other conditions, the test is typically used alongside other diagnostic tools to confirm a diagnosis.

    Cancer Antigen 125 (CA 125) Test Results and Interpretation

    CA-125, a tumour marker, is used to monitor the treatment and progress of individuals with serous ovarian cancer. The table below details the normal blood levels of CA-125 and the conditions associated with its elevation:

    TestBiological Reference (U/mL)Interpretation
    CA-125 (Serum)<35CA-125 is found in a high percentage of non-mucinous ovarian tumours of epithelial origin. Elevated levels are also found in ovarian cysts, endometriosis, cervicitis, cirrhosis, hepatitis, malignancy of endometrium, breast, or gastrointestinal tract.

    FAQs on Cancer Antigen 125 (CA 125) Test

    The cost of a Cancer Antigen 125 test in Mumbai is 1600. This cost includes rapid home sample collection from your desired location.

    Yes, Orange Health Labs offers home sample collection for the CA-125 test in Mumbai. A trained and experienced eMedic will visit your chosen location within 60 minutes of booking or at a time that suits you, making the process convenient and stress-free.

    The CA-125 test plays a key role in the diagnosis, treatment, and monitoring of ovarian cancer. It is particularly useful for screening those at high risk or experiencing symptoms of ovarian cancer. The test is frequently used during ovarian cancer treatment to gauge how well the treatment is working and to check for cancer recurrence.

    No, you do not need to fast before a CA-125 test.

    To schedule a blood test or health checkup using our platform, follow these steps:

    • Find the Test : Locate the CA-125 test test Mumbai or at home and click on Orange Health’s page.

    • Review and Verify : Select the test, review any necessary prerequisites, input your location, and complete the booking by choosing a time for sample collection.

    • Collection of Sample : A trained eMedic will come to your home at the chosen time to collect the sample.

    • Lab Processing : Your sample will be sent to our ICMR-approved and NABL-accredited labs for examination.

    • Receive Results : You’ll receive your results via email or WhatsApp within 68 hours and can also access them through our app.

    The normal level for the CA-125 test is <35 U/mL.

    Expect a swift turnaround for the CA-125 test with Orange Health Labs. Typically, the test report is delivered within 68 hours of sample collection.

    How often you undergo CA-125 testing depends on your individual health condition. For patients being treated for ovarian cancer, the test is conducted regularly to monitor treatment progress and detect any recurrence. If you are at high risk or have symptoms of ovarian cancer, your doctor might suggest further testing based on the outcomes.

    The CA-125 test measures only a single parameter: the level of Cancer Antigen 125 (CA-125) protein in the blood sample.

    The CA-125 test does not require fasting.

    Orange Health provides the fastest CA-125 test services right at your home across Mumbai, removing the need for a physical lab visit. We cater to numerous localities, including but not limited to Colaba, Nariman Point, Marine Drive, Malabar Hill, Vashi, Belapur, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. CA-125 Blood Test (Ovarian Cancer) [Internet]. Medlineplus.gov. 2022 [cited 2024 Aug 2].  Available from:  http://medlineplus.gov
    2. CA-125 Blood Test: Results, Normal Range & What To Expect [Internet]. Cleveland Clinic. 2022 [cited 2024 Aug 2].  Available from:  https://my.clevelandclinic.org/health/diagnostics/17830-ca-125-blood-test
    3. Gandhi T, Zubair M, Bhatt H. Cancer Antigen 125 [Internet]. Nih.gov. StatPearls Publishing; 2024 [cited 2024 Aug 2].  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK562245/