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    What is Apolipoprotein A1 (Apo-A1) Test?

    The Apo A1 test, or Apolipoprotein A1 test, determines the level of apolipoprotein A1 in the bloodstream. This protein is essential for cholesterol transport as it helps form lipoproteins. Apo A1 is a core component of high-density lipoprotein (HDL) cholesterol, also known as "good cholesterol," which aids in eliminating excess cholesterol from the blood and reducing arterial buildup.

    A decrease in Apo A1 levels may suggest fewer HDL particles, raising the risk of cardiovascular diseases and circulatory issues. Healthcare providers may order this test for individuals with high cholesterol, a family history of heart disease, or hyperlipidaemia. It is also useful for assessing the impact of treatments and lifestyle adjustments on cholesterol levels. Low Apo A1 levels can result from conditions such as kidney disease, diabetes, smoking, or certain medications. High levels, however, are typically not a concern and may be linked to exercise, weight loss, or pregnancy.

    While not a commonly performed test, the Apo A1 test offers additional insights into cardiovascular health and serves as a complement to standard cholesterol testing when needed.

    Apolipoprotein A1 (Apo-A1) Test Parameters

    The Apo A1 test is designed to measure the amount of Apolipoprotein A1 in the blood. Apo A1 is a primary protein component of HDL, accounting for about 65% of its structure. It plays a crucial role in HDL particle formation and activates lecithin cholesterol acyltransferase (LCAT), an enzyme that modifies cholesterol into a form the body can eliminate.

    HDL’s essential function is to shuttle excess cholesterol from tissues to the liver, where it is processed and excreted. If Apo A1 levels are too low, this cholesterol-clearing process may be less effective, heightening the risk of heart disease and vascular disorders. Individuals with atherosclerosis tend to have lower Apo A1 levels. While genetic factors can influence Apo A1 levels, not all genetic changes result in heart disease.

    Doctors often evaluate Apo A1 alongside Apolipoprotein B (Apo B) to gain a clearer understanding of cardiovascular risk. This comparison offers deeper insights into heart health than conventional cholesterol tests alone.

    Apolipoprotein A1 (Apo-A1) Test Preparation

    To prepare for an Apolipoprotein A1 test at home:

    Prerequisites

    No fasting or prior preparations are required.

    Best Time to Get Tested

    This test can be done at any time of the day.

    Who Should Get an Apolipoprotein A1 Test?

    The Apo A1 test is advised for individuals with high cholesterol, a family history of heart disease, or those actively managing their cholesterol levels.

    Cautions Before Taking Apolipoprotein A1 Test

    There are no special precautions needed before taking this test.

    Why Take the Apolipoprotein A1 (Apo-A1) Test?

    The Apolipoprotein A1 test may be recommended for:

    • The Apolipoprotein A1 test may be recommended for:

    • Monitoring cholesterol regulation after starting medication or lifestyle adjustments

    • Measuring the Apo A1/Apo B ratio for better insight into cholesterol distribution

    • Individuals with consistently high cholesterol or hyperlipidaemia

    • Detecting genetic disorders that contribute to low HDL cholesterol levels

    • Individuals with a family history of early-onset heart disease or heart attacks

    Since it is more precise than standard HDL cholesterol tests, the Apo A1 test provides a clearer picture of cardiovascular health and disease risk.

    FAQs on Apolipoprotein A1 (Apo-A1) Test in Mumbai

    The Apo A1 test in Mumbai is priced at ₹650. This fee covers a home sample collection, conducted within 60 minutes of confirming the appointment, with results available in 3 hours.

    Yes, Orange Health Labs provides home sample collection services for the Apo A1 test in Mumbai. A professional eMedic will collect your sample within 60 minutes post-booking, based on slot availability.

    The Apo A1 test evaluates a crucial protein in HDL cholesterol that helps determine heart disease risk. It is especially recommended for those with a history of high cholesterol or hereditary heart conditions.

    Fasting is usually not required for this test. Nonetheless, it’s best to follow your doctor's advice if specific preparation is needed.

    To schedule an Apolipoprotein A1 test with Orange Health Labs in Mumbai, follow these steps:

    • Locate the test : Go to the Orange Health website and search for the Apolipoprotein A1 test in Mumbai.

    • Schedule your appointment : Choose the test, check any necessary instructions, provide your location, and pick a time that suits you.

    • Home sample collection : A certified eMedic will arrive at your location to collect the blood sample after your booking is confirmed.

    • Lab analysis : The sample is processed at an ICMR-certified and NABL-accredited lab.

    • Get your results : Your test results will be sent via email or WhatsApp within 3 hours and will also be available on the Orange Health app.

    The normal reference range for Apolipoprotein A1 falls between 105 and 175 mg/dL.

    After booking confirmation, an eMedic arrives within 60 minutes for sample collection. The results are typically ready within 3 hours.

    The frequency of this test is determined by your health condition and your physician’s recommendation. Always consult your doctor for an appropriate testing schedule.

    It measures only Apolipoprotein A1 levels, an essential protein found in HDL (good cholesterol).

    Orange Health provides home sample collection for this test in several parts of Mumbai, including Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Apolipoprotein A-1 | Pathology Tests Explained [Internet].  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=Apolipoprotein+A-1
    2. Apolipoprotein A1 – Supra-Regional Assay Service [Internet].  Available from:  https://www.sas-centre.org/assays/cardiovascular-biomarkers/apolipoprotein-a1