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    Anti Mitochondrial antibody (IFA)2399210012% off
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    What Is an Anti Mitochondrial antibody (IFA) Test?

    The Anti-Mitochondrial Antibody (AMA) test identifies antimitochondrial antibodies in the blood, which serve as a highly specific and sensitive marker for primary biliary cholangitis/cirrhosis (PBC), a chronic autoimmune liver disease. These antibodies are found in more than 95% of PBC patients.

    PBC typically affects middle-aged individuals and is often linked to other autoimmune disorders, such as Sjögren’s syndrome. The condition leads to progressive liver damage as the immune system attacks bile ducts, which disrupts liver function. The Immunofluorescence Assay (IFA) method used in the test provides precise detection of AMA, particularly M2 antibodies, which are strongly connected to PBC. Early diagnosis through the AMA test is vital, as early treatment can help slow the disease's progress, reduce liver damage, and prevent liver failure.

    This test is essential for diagnosing autoimmune liver diseases, monitoring liver function, and distinguishing PBC from other liver disorders. If you experience persistent liver function abnormalities or symptoms of PBC, taking an Anti-Mitochondrial Antibody test at home could be beneficial for further investigation.

    Anti Mitochondrial antibody (IFA) Test Parameters

    The Anti-Mitochondrial Antibody test measures antimitochondrial antibody levels in the blood.

    These antibodies target mitochondria, the energy-producing parts of cells, which can result in liver damage over time. The presence of AMA is primarily linked to autoimmune liver diseases like primary biliary cholangitis (PBC). However, these antibodies may also be found in a small proportion of people with autoimmune hepatitis and other liver diseases. AMA can be present in the bloodstream years before symptoms or noticeable liver dysfunction occur, which is why the test is valuable for detecting autoimmune liver damage at an early stage.

    Anti Mitochondrial antibody (IFA) Test Preparation

    Preparing for an Anti-Mitochondrial Antibody (IFA) test at home is easy with the following details:

    • Prerequisites Fasting is not typically required for the Anti-Mitochondrial Antibody (IFA) test. However, you should consult your doctor if any specific preparations are needed.

    • Best Time to Get Tested The AMA test can be taken at any time that fits your schedule, offering convenience and flexibility.

    • Who Should Get an Anti-Mitochondrial Antibody (IFA) Test? This test is recommended for individuals experiencing symptoms of PBC or other autoimmune liver diseases. It may also be helpful for those with consistently abnormal liver function tests, unexplained jaundice, or chronic fatigue associated with liver issues.

    • Cautions Before Taking an Anti-Mitochondrial Antibody (IFA) Test Make sure to inform your doctor about any medications you are taking, recent infections, or autoimmune conditions, as these factors could influence your test results.

    Why Take the Anti Mitochondrial antibody (IFA) Test?

    The Anti-Mitochondrial Antibody test plays a vital role as it can:

    Diagnose PBC : It is essential for diagnosing primary biliary cholangitis (PBC), a long-term autoimmune liver disease.

    Differentiate between liver conditions : The test helps differentiate PBC from other liver problems like viral hepatitis, alcoholic cirrhosis, and bile duct obstructions.

    If you have symptoms of PBC-related liver damage, your doctor may suggest this test. These symptoms include:

    • Itching (pruritus)

    • Swelling in the ankles or abdomen due to fluid buildup

    • Persistent fatigue

    • Bone, muscle, and joint pain

    • Unexplained weight loss

    • Nausea and loss of appetite

    • Yellowing of the skin and eyes (jaundice)

    • Dark urine

    • Dry eyes and mouth (linked to Sjögren’s syndrome)

    • Abdominal pain or discomfort

    FAQs on the Anti Mitochondrial antibody (IFA) Test in Mumbai

    The price for the Anti-Mitochondrial Antibody (IFA) test in Mumbai is ₹2100. It covers home sample collection within 60 minutes and ensures test results are available within 136 hours.

    Yes, Orange Health Labs offers the convenience of home sample collection for the Anti-Mitochondrial Antibody (IFA) test. A trained eMedic will arrive at your location within 60 minutes after booking to collect the sample.

    The Anti-Mitochondrial Antibody test is primarily used to diagnose primary biliary cholangitis (PBC), the Anti-Mitochondrial Antibody test also helps differentiate PBC from other liver disorders, such as viral hepatitis, alcoholic cirrhosis, and bile duct blockages.

    No fasting is required prior to the Anti-Mitochondrial Antibody test; however, it's recommended to follow any instructions your doctor may give.

    You can arrange the Anti-Mitochondrial Antibody (IFA) test with Orange Health Labs by following these steps:

    • Find the Test: Look for the "Anti-Mitochondrial Antibody (IFA) test" on the Orange Health Labs platform.

    • Confirm Your Appointment: Provide your details, choose your location, and pick a time that works best for sample collection.

    • Sample Collection: A skilled eMedic will collect your sample from your home or office.

    • Laboratory Analysis: Your sample will be processed at a laboratory that is both NABL-accredited and ICMR-approved.

    • Receive Your Results: The test results will be sent to you via email or WhatsApp within 136 hours.

    The standard levels for the Antimicrobial Antibody Test are as follows:

    • Negative: ≤20.0 units

    • Equivocal: 20.1-24.9 units

    • Positive: ≥25.0 units.

    Results for the Anti-Mitochondrial Antibody test are generally available within 136 hours of sample collection.

    How often this test is carried out depends on your doctor’s advice. It may be repeated periodically for those diagnosed with PBC or other autoimmune liver conditions to monitor the progression of the disease and the effectiveness of treatment.

    The AMA test is designed to detect anti-mitochondrial antibodies in the blood, which serve as markers for autoimmune liver conditions, particularly PBC.

    Orange Health Labs offers home sample collection for the Anti-Mitochondrial Antibody (IFA) test across multiple localities in Mumbai, including but not limited Colaba, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, and Kurla. You can conveniently book the test and have your sample collected from the comfort of your home or office.

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    References

    1. Antimitochondrial Antibody and Antimitochondrial M2 Antibody - Health Encyclopedia - University of Rochester Medical Center.  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=antimitochondrial_antibody_m2
    2. Anti-mitochondrial antibody (AMA) [Internet]. South Tees Hospitals NHS Foundation Trust.  Available from:  https://www.southtees.nhs.uk/services/pathology/tests/anti-mitochondrial-antibody-ama/
    3. Antimitochondrial antibody: MedlinePlus Medical Encyclopedia [Internet].  Available from:  https://medlineplus.gov/ency/article/003529.htm
    4. Antimitochondrial antibody Information | Mount Sinai - New York.  Available from:  https://www.mountsinai.org/health-library/tests/antimitochondrial-antibody
    5. AMA: Mitochondrial Ab, McLendon Clinical Laboratories | UNC Medical Center, Hospitals – Chapel Hill, NC.  Available from:  https://www.uncmedicalcenter.org/mclendon-clinical-laboratories/available-tests/ama-mitochondrial-ab/