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    Cancer Antigen 125 (CA 125)2400160033% off
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    What Is Cancer Antigen 125 (CA 125) Test?

    The Cancer Antigen 125 (CA-125) test measures the concentration of a protein known as CA-125 in the blood. This protein serves as a tumour marker, which can be elevated in certain types of cancer, particularly ovarian cancer. The ovaries are reproductive organs in females that produce eggs and secrete hormones. CA-125 is produced by the cells lining the ovaries and other organs like the fallopian tubes and uterus. Elevated levels of CA-125 can be observed in various cancers as well as in other medical conditions.

    The CA-125 test is commonly used to screen postmenopausal women who are at a high risk of developing ovarian cancer, such as those with a family history or a genetic predisposition to the disease. It is also used to evaluate individuals presenting symptoms that may indicate ovarian cancer. This test is particularly valuable for monitoring the effectiveness of ovarian cancer treatment and for checking for cancer recurrence after treatment.

    If you live in Hyderabad and have risk factors or symptoms that could be related to ovarian cancer, you may opt to have a CA-125 test done at home, with your doctor's recommendation, to monitor your health or assess your risk.

    Cancer Antigen 125 (CA 125) Test Parameters

    The CA-125 test specifically measures a single parameter: the CA-125 protein levels in the blood.

    CA-125 is a tumour marker that is produced by ovarian cancer cells and the cells lining various organs, including the endometrium, fallopian tubes, lungs (pleura), gut (peritoneum), and heart (pericardium). This test is often used in serological evaluations when ovarian cancer is suspected and is essential for monitoring patients who have been diagnosed with epithelial ovarian cancers. CA-125 is believed to play a role in suppressing the immune system's ability to target and eliminate diseased cells, such as those infected or cancerous.

    Under normal circumstances, CA-125 remains on the cell surface, protected by barriers that prevent it from entering the bloodstream. However, when these barriers are compromised by cancerous cells, CA-125 leaks into the blood, resulting in elevated levels detectable by the test. Additionally, CA-125 may interact with other cellular proteins to facilitate the growth and spread of cancer.

    Elevated CA-125 levels are commonly associated with ovarian cancer, particularly epithelial ovarian cancer, but can also be seen in other cancers, such as those of the uterus, breast, and fallopian tubes. Non-cancerous conditions like ovarian cysts, fibroids, and endometriosis can also cause elevated CA-125 levels, as can normal physiological conditions like the first trimester of pregnancy, the postpartum period, and menstruation.

    Cancer Antigen 125 (CA 125) Test Preparation

    Getting ready for a Cancer Antigen 125 test at home is simple with these steps:

    Pre-requisites

    There's no need to fast before taking the Cancer Antigen 125 (CA-125) test.

    Best Time to Get Tested

    The CA-125 test can be performed at any time of the day.

    Who Should Get a Cancer Antigen 125 (CA-125) Test

    The CA-125 test is recommended for women who need to diagnose ovarian cancer, particularly those with symptoms or risk factors like a family history or genetic mutations. It is also suitable for monitoring patients who have been diagnosed with ovarian cancer and are currently undergoing treatment. Regular testing may be advised after treatment to detect any recurrence of the cancer.

    Cautions Before Taking a Cancer Antigen 125 (CA-125) Test

    Be aware that CA-125 levels can be elevated due to non-cancerous conditions, including pregnancy, menstruation, and fibroids. It's advisable to consult your doctor about any precautions to take before the test.

    Why Take the Cancer Antigen 125 (CA 125) Test?

    The CA-125 test is a crucial tool in managing ovarian cancer and assessing related risks. Here’s when you might need this test:

    • Monitoring Treatment Progress : If you have been diagnosed with ovarian cancer, regular CA-125 tests are conducted during treatment to evaluate the effectiveness of the therapy. A reduction in CA-125 levels usually indicates that the treatment is working.

    • Checking for Recurrence : After completing cancer treatment, CA-125 levels may be monitored periodically, whether every few months or annually, to detect if the cancer has returned.

    • Evaluating Pelvic Lumps : When a suspicious lump is discovered in the pelvic region through imaging tests like ultrasound, CA-125 levels can help determine whether the lump could be ovarian cancer.

    • Assessment of High-Risk Individuals

      • A family history of ovarian, breast, or colorectal cancer.

      • Specific genetic mutations, including BRCA1 or BRCA2.

      • A personal history of ovarian, breast, colorectal, or uterine cancer.

      • Hereditary conditions like Lynch syndrome, which increase the risk of various cancers.

    Since elevated CA-125 levels can occur in several other conditions, the CA-125 test is often used in conjunction with other diagnostic tools to confirm a diagnosis.

    Cancer Antigen 125 (CA 125) Test Results and Interpretation

    CA-125 serves as a tumour marker to track the treatment and progress of patients with serous ovarian cancer. The table below outlines the normal range of CA-125 levels in the blood and the conditions linked to elevated levels:

    TestBiological Reference (U/mL)Interpretation
    CA-125 (Serum)<35CA-125 is found in a high percentage of non-mucinous ovarian tumours of epithelial origin. Elevated levels are also found in ovarian cysts, endometriosis, cervicitis, cirrhosis, hepatitis, malignancy of endometrium, breast, or gastrointestinal tract.

    FAQs on Cancer Antigen 125 (CA 125) Test

    The cost of a Cancer Antigen 125 test in Hyderabad is 1600. This price includes quick home sample collection from your desired location.

    Yes, Orange Health Labs provides home sample collection services for the CA-125 test in Hyderabad. A qualified and professional eMedic will reach your preferred location within 60 minutes of booking or at a time that best fits your schedule, ensuring a seamless and convenient experience.

    The CA-125 test is primarily utilised for diagnosing, treating, and monitoring ovarian cancer. It aids in screening individuals who are at high risk or show symptoms of ovarian cancer. This test is most often employed during ovarian cancer treatment to evaluate the effectiveness of the therapy and to detect any recurrence.

    No, you are not required to fast before a CA-125 test.

    Booking a blood test or health checkup through our platform involves the following steps:

    • Find the Test : Search for the CA-125 test in Hyderabad or at home and go to Orange Health’s page.

    • Review and Verify : Choose the test, review the prerequisites, provide your location, and finalise your booking by selecting a time for sample collection.

    • Collection of Sample : At the scheduled time, a qualified eMedic will visit your home to collect the sample.

    • Lab Processing : The sample will be dispatched to our ICMR-approved and NABL-accredited laboratories for processing.

    • Receive Results : You will receive your results via email or WhatsApp within 80 hours, and they will also be available through our app.

    The normal level for the CA-125 test is <35 U/mL.

    With Orange Health Labs, you can anticipate a fast turnaround time for the CA-125 test. The report is usually provided within 80 hours after the sample is collected.

    The frequency of CA-125 testing is determined by your specific health situation. For those receiving treatment for ovarian cancer, the test is performed regularly to track the effectiveness of the therapy and to check for signs of recurrence. If you're at high risk or exhibiting symptoms of ovarian cancer, your doctor may recommend additional testing based on the results.

    The CA-125 test focuses on a single parameter: the concentration of Cancer Antigen 125 (CA-125) protein in the blood sample.

    The CA-125 test does not require fasting.

    Experience the convenience of Orange Health’s speedy CA-125 test services at home anywhere in Hyderabad, avoiding the need for a physical lab visit. We cover various localities, such as Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. CA-125 Blood Test (Ovarian Cancer) [Internet]. Medlineplus.gov. 2022 [cited 2024 Aug 2].  Available from:  http://medlineplus.gov
    2. CA-125 Blood Test: Results, Normal Range & What To Expect [Internet]. Cleveland Clinic. 2022 [cited 2024 Aug 2].  Available from:  https://my.clevelandclinic.org/health/diagnostics/17830-ca-125-blood-test
    3. Gandhi T, Zubair M, Bhatt H. Cancer Antigen 125 [Internet]. Nih.gov. StatPearls Publishing; 2024 [cited 2024 Aug 2].  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK562245/