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    Anti Smooth Muscle antibody (Anti-SMA) (IFA)2626200024% off
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    What is Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti Smooth Muscle Antibody (ASMA) blood test is a test conducted to identify the presence of smooth muscle antibodies (SMAs) in the bloodstream. These autoantibodies mistakenly attack liver cells, triggering inflammation and damage. The test plays a key role in diagnosing autoimmune hepatitis (AIH), a chronic liver disease where the immune system wrongly identifies liver tissue as a threat.

    Ordinarily, the immune system shields the body from harmful pathogens like viruses and bacteria. However, AIH produces self-targeting antibodies such as ASMAs, leading to progressive liver damage. If left untreated, AIH can cause complications like cirrhosis. Treatment typically involves medications that suppress immune activity, helping to slow disease progression.

    There are two primary types of AIH:

    • Type 1, the most common, affects both adults and children, especially women, and is linked to ASMAs.

    • Type 2, which is rarer and mainly seen in girls, involves additional antibodies such as LKM-1.

    Doctors often recommend the ASMA test alongside other autoantibody tests, such as ANA and LKM-1 antibody tests, to confirm a diagnosis.

    Residents of Gurgaon can conveniently book this test from home with a simple sample collection process and quick result delivery.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Parameters

    The ASMA test is a diagnostic test that identifies antibodies targeting smooth muscle proteins in the blood. These antibodies attack proteins found in smooth muscles, which are present in the walls of hollow organs like the stomach, intestines, and blood vessels. Because these proteins are also abundant in liver cells, elevated ASMA levels are often linked to autoimmune hepatitis (AIH) and other liver diseases.

    By detecting whether the immune system is mistakenly attacking the liver, this test aids in diagnosing AIH. To improve diagnostic accuracy, doctors frequently order this test alongside ANA and LKM-1 antibody tests.

    There are multiple ways to analyse ASMA levels, which help in identifying specific antibodies and their concentration, providing more detailed insights into liver conditions. Since ASMA was first detected in individuals with liver diseases, it has been essential in diagnosing and managing AIH. Early detection allows for timely intervention, reducing the risk of liver fibrosis, cirrhosis, and failure. If ASMA is found, treatment focuses on regulating the immune system to safeguard the liver.

    Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test Preparation

    To prepare for the Anti-Smooth Muscle Antibody (ASMA) test at home, check these prerequisites:

    • Prerequisites :

    No fasting or special preparation is required before the test.

    • Best Time to Get Tested :

    You can schedule your test at any time during the day.

    • Who Should Get an Anti-Smooth Muscle Antibody Test? :

    If you have unexplained liver-related symptoms like yellowing of the skin (jaundice), persistent fatigue, or abdominal pain, or if your liver function tests are abnormal, this test may help determine whether you have autoimmune hepatitis.

    • Cautions Before Taking an Anti-Smooth Muscle Antibody Test :

    No special precautions are necessary before undergoing this test.

    Why Take the Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test?

    The Anti-Smooth Muscle Antibody test is often recommended if you have:

    • Persistent fatigue

    • Yellowing of the skin or eyes (jaundice)

    • Unexplained nausea or loss of appetite

    • Abdominal discomfort or pain

    • Dark-coloured urine

    • Light or clay-coloured stool

    • Stiff or aching joints

    • Skin conditions such as rashes, vitiligo, acne, or psoriasis

    Sometimes, autoimmune hepatitis (AIH) develops silently with no early symptoms. If a routine liver function test reveals abnormalities, an ASMA test may help confirm the cause. If ASMA levels are high, a liver biopsy or additional tests might be necessary to assess the extent of liver damage.

    FAQs on Anti Smooth Muscle antibody (Anti-SMA) (IFA) Test in Gurgaon

    The test is priced at ₹2000 in Gurgaon. This cost includes a home sample collection service, with a technician arriving at your doorstep within 60 minutes of schedule. The results will be shared within 125 hours after the sample is collected.

    Yes, Orange Health Labs provides home sample collection services for the Anti-Smooth Muscle Antibody test. A trained professional will visit your home within 60 minutes to collect the sample.

    This test is used to check for autoimmune liver diseases like autoimmune hepatitis (AIH) by identifying antibodies that mistakenly attack liver cells. It also helps in assessing liver damage and determining the need for further diagnostic tests, such as a biopsy.

    No, fasting is not required. You can take the test without any dietary restrictions.

    Here’s how you can book an Anti-Smooth Muscle Antibody test with Orange Health Labs in Gurgaon:

    • Search the test: Search for the test online and select Orange Health Labs.

    • Enter details: Provide your contact details, address, and preferred time for sample collection.

    • Sample Collection: A certified eMedic professional will visit your location and collect the blood sample.

    • Testing and Analysis: Your sample will be analysed at a NABL-certified, ICMR-approved laboratory, and the results will be sent via email or WhatsApp within 125 hours.

    A negative result is considered normal, meaning no autoantibodies are present. A positive test suggests potential autoimmune liver disease, such as autoimmune hepatitis.

    Your test report will be delivered within 125 hours after sample collection.

    Your doctor will determine if a follow-up test is necessary based on your symptoms and medical history.

    The test identifies autoantibodies targeting smooth muscle to aid in diagnosing autoimmune liver conditions.

    This test is available in several Gurgaon neighbourhoods, including DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, DLF Phase 5, Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56.

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    • We do not accept cash payments
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    References

    1. Smooth Muscle Antibody (SMA) Test: MedlinePlus Medical Test. 2. Anti-smooth muscle antibody - UF Health.  Available from:  https://medlineplus.gov/lab-tests/smooth-muscle-antibody-sma-test/
    2. Zhang WC, Zhao FR, Chen J, Chen WX. Meta-Analysis: Diagnostic Accuracy of Antinuclear Antibodies, Smooth Muscle Antibodies and Antibodies to a Soluble Liver Antigen/Liver Pancreas in Autoimmune Hepatitis.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3961308/#s4