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    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA2924262510% off
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    What Is Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test that helps identify certain proteins made by the immune system. These proteins are meant to fight infections but, in some cases, they mistakenly attack healthy white blood cells like neutrophils and monocytes.

    This test is useful for diagnosing ANCA-associated vasculitis, a condition where blood vessels become inflamed. This can make them narrow, blocked, or weakened, affecting organs such as the kidneys, lungs, eyes, and skin. Common early symptoms include fever, fatigue, body aches, and weight loss. Without treatment, vasculitis can cause severe organ damage.

    Two important proteins linked to ANCA-associated vasculitis include:

    • Myeloperoxidase (MPO): Often seen in microscopic polyangiitis (MPA), which affects small blood vessels.

    • Proteinase 3 (PR3): Mainly found in granulomatosis with polyangiitis (GPA) that affects the lungs and sinuses.

    Doctors may also recommend further tests, such as PR3 ANCA, inflammation markers, full blood counts, and kidney function tests, to confirm the diagnosis and keep track of treatment progress.

    For those staying in Gurgaon, the option of an Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home ensures easy sample collection and fast results.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Parameters

    The ANCA test measures the presence of autoantibodies in the blood, specifically PR3 and MPO. These autoantibodies mistakenly target certain proteins in the body.

    The two types of ANCAs are:

    cANCA (cytoplasmic ANCA)

    Targets PR3, a protein that helps control blood cell production and can trigger programmed cell death.

    pANCA (perinuclear ANCA)

    Attacks MPO, a protein that plays a key role in fighting infections.

    In the presence of ANCAs, neutrophils get activated and release harmful chemicals that lead to inflammation and blood vessel damage. This can affect organs such as the kidneys, lungs, and skin. As neutrophils pass through blood vessel walls, they keep releasing chemicals, which further intensifies the inflammation and tissue damage.

    Although levels of ANCA, PR3, and MPO can go up and down, some individuals can keep producing these autoantibodies even when they are not detectable in tests. A positive ANCA test is mostly associated with vasculitis but can also be seen in inflammatory bowel disease, rheumatoid arthritis, with certain medications, and infections such as respiratory infections and endocarditis.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Preparation

    If you are taking the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, here’s what you should know beforehand:

    • Prerequisites: No special requirements are needed, and fasting is not necessary before the test.

    • Best Time to Get Tested: You can take the ANCA test at any time that suits you.

    • Who Should Get an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test? If you experience fever, unexplained fatigue, joint pain, or weight loss, or have symptoms affecting your lungs, nervous system, skin, or kidneys, an ANCA test can help check for autoimmune vasculitis.

    • Cautions Before Taking an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test: No special precautions are required before taking the ANCA test.

    Why Take the Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    You may need the ANCA test if you experience:

    • General symptoms with no clear cause, such as fatigue, fever, weight loss, muscle pain, joint pain, or night sweats.

    • Symptoms affecting specific organs:

      • Eyes, ears, or nose: Blurred vision, sinus infections, or hearing problems.

      • Skin: Rashes, unusual bruising, or itching.

      • Lungs: Difficulty breathing or coughing up blood.

      • Kidneys: Blood or protein in the urine.

      • Nervous system: Numbness, tingling, or sudden shooting pains.

      • Digestive system: Stomach pain, diarrhoea, or vomiting blood.

    • Suspected vasculitis conditions like GPA or MPA.

    • Inflammatory bowel disease, particularly if you have ongoing diarrhoea, bloody stools, or a fever.

    • Regular testing to monitor autoimmune vasculitis if already diagnosed.

    The ANCA test helps identify vasculitis early, allowing for better symptom control and preventing long-term damage to organs.

    FAQs on Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test in Gurgaon

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test in Gurgaon is priced at ₹2625. The package includes a home sample collection, arranged within 60 minutes of booking. Orange Health Labs ensures that your test results are delivered within 69 hours of collecting the sample.

    Yes, with Orange Health Labs, you can get the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home. A certified eMedic professional will visit you within 60 minutes of booking to collect your blood sample.

    An ANCA test helps diagnose autoimmune diseases such as vasculitis. It works by detecting autoantibodies in the blood that may cause inflammation and harm blood vessels and organs.

    No, fasting is not necessary for the ANCA test.

    You can easily book the Anti Neutrophil Cytoplasmic Antibody (ANCA) test in Gurgaon with Orange Health Labs by following these steps:

    • Search for the Test: Look up "Anti Neutrophil Cytoplasmic Antibody (ANCA) Test" and select Orange Health Labs from the search results.

    • Confirm Your Booking: Provide your details, select your location, and schedule a sample collection at a time that suits you.

    • Sample Collection: A certified eMedic professional will visit your home or chosen location to take your blood sample.

    • Analysis and Results: The sample will be tested at our NABL-accredited, ICMR-approved laboratory, and results will be shared via email or WhatsApp within 69 hours.

    A negative ANCA test result is considered normal, as it means no p-ANCA or c-ANCA autoantibodies were found, reducing the likelihood of autoimmune vasculitis. A positive result suggests abnormal levels and warrants further investigation for autoimmune diseases.

    You can expect the results of the ANCA test within 69 hours after your sample has been collected.

    The need for repeated ANCA tests varies based on your health condition and should be guided by your doctor’s recommendation.

    In the ANCA test, antibodies like p-ANCA, c-ANCA, PR3, and MPO are measured.

    You can access the ANCA test in various areas of Gurgaon. These include but are not limited to DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, DLF Phase 5, Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56.

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    References

    1. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: MedlinePlus Medical Test.  Available from:  https://medlineplus.gov/lab-tests/antineutrophil-cytoplasmic-antibodies-anca-test/
    2. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: What It Is. 3. Antineutrophil cytoplasmic antibodies (ANCA) | Pathology Tests Explained. 4. Khalid N, Aeddula NR. Antinuclear Cytoplasmic Antibody [Internet]. PubMed. Treasure Island (FL). 5. The value of anti-neutrophil cytoplasmic antibodies (ANCA) testing for the diagnosis of ANCA-associated vasculitis, a systematic review and meta-analysis.  Available from:  https://my.clevelandclinic.org/health/diagnostics/22512-anca-test