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    Anti Mitochondrial antibody (IFA)2399210012% off
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    What Is an Anti Mitochondrial antibody (IFA) Test?

    The Anti-Mitochondrial Antibody (AMA) test detects the presence of antimitochondrial antibodies in the blood. AMA is a specific and sensitive indicator for primary biliary cholangitis/cirrhosis (PBC), a chronic autoimmune liver disease. Over 95% of people with PBC test positive for these antibodies.

    PBC mainly affects middle-aged individuals and is frequently linked to other autoimmune conditions like Sjögren’s syndrome. The disease causes progressive liver scarring as the immune system attacks bile ducts, impairing the liver's function.

    The IFA (Immunofluorescence Assay) method used in this test allows for accurate detection of AMA, especially M2 antibodies strongly associated with PBC. Early detection through the AMA test is important because prompt treatment can slow the disease's progression, reduce liver damage, and help prevent liver failure.

    This test is critical for diagnosing autoimmune liver diseases and monitoring liver health, as it helps differentiate PBC from other liver disorders. If you have ongoing liver function abnormalities or symptoms pointing to PBC, an Anti-Mitochondrial Antibody test at home may aid in further diagnosis.

    Anti Mitochondrial antibody (IFA) Test Parameters

    The Anti-Mitochondrial Antibody test measures the presence of antimitochondrial antibodies in the blood.

    These antibodies are produced against mitochondria, the cell's energy-producing components. Over time, they can cause damage to the liver. The detection of AMA in the blood is strongly associated with autoimmune liver diseases such as primary biliary cholangitis (PBC). Additionally, antimitochondrial antibodies can be found in a small number of individuals with autoimmune hepatitis and other liver conditions. AMAs can appear in the blood years before any symptoms or significant liver abnormalities are noticeable, making early detection crucial for identifying autoimmune liver damage.

    Anti Mitochondrial antibody (IFA) Test Preparation

    Here’s what you need to know to prepare for an Anti-Mitochondrial Antibody (IFA) test at home:

    • Prerequisites Fasting is typically not necessary before the Anti-Mitochondrial Antibody (IFA) test. However, it’s best to consult your doctor for any specific preparation recommendations.

    • Best Time to Get Tested The AMA test can be done at any time that is convenient for you, offering flexibility and ease.

    • Who Should Get an Anti-Mitochondrial Antibody (IFA) Test? The test is suggested for those showing symptoms of PBC or other autoimmune liver diseases. It may also be recommended for individuals with persistently abnormal liver function tests, unexplained jaundice, or chronic fatigue linked to liver conditions.

    • Cautions Before Taking an Anti-Mitochondrial Antibody (IFA) Test Be sure to inform your doctor about any ongoing medications, recent infections, or existing autoimmune conditions, as these could affect your test results.

    Why Take the Anti Mitochondrial antibody (IFA) Test?

    The Anti-Mitochondrial Antibody test is crucial because it can:

    Diagnose PBC : The AMA test is primarily used to diagnose primary biliary cholangitis (PBC), a chronic autoimmune liver disease.

    Differentiate liver conditions : It helps distinguish PBC from other liver disorders, such as viral hepatitis, alcoholic cirrhosis, and bile duct blockages.

    A doctor may recommend this test if you show symptoms associated with liver damage from PBC, such as:

    • Persistent fatigue

    • Unexplained weight loss

    • Nausea and loss of appetite

    • Abdominal pain or discomfort

    • Bone, muscle, and joint pain

    • Itching (pruritus)

    • Yellowing of the skin and eyes (jaundice)

    • Swelling in the ankles or abdomen due to fluid buildup

    • Dry eyes and mouth (linked to Sjögren’s syndrome)

    • Dark urine

    FAQs on the Anti Mitochondrial antibody (IFA) Test in Gurgaon

    The Anti-Mitochondrial Antibody (IFA) test in Gurgaon costs ₹2100. This includes home sample collection within 60 minutes, with results delivered within 123 hours.

    Yes, Orange Health Labs provides home sample collection for the Anti-Mitochondrial Antibody (IFA) test. A trained eMedic will come to your location within 60 minutes of your booking to collect your sample.

    The Anti-Mitochondrial Antibody test is mainly used to identify primary biliary cholangitis (PBC), a long-term autoimmune liver condition. It also aids in distinguishing PBC from other liver diseases like viral hepatitis, alcoholic cirrhosis, and bile duct obstructions.

    Fasting is not necessary before the Anti-Mitochondrial Antibody test, but it's advisable to follow any specific instructions provided by your doctor.

    To book your Anti-Mitochondrial Antibody (IFA) test with Orange Health Labs, follow these steps:

    • Find the Test: Search for the "Anti-Mitochondrial Antibody (IFA) test" on the Orange Health Labs platform.

    • Confirm Your Appointment: Enter your details, select your location, and choose a convenient time for sample collection.

    • Sample Collection: An experienced eMedic will collect your sample from either your home or office.

    • Laboratory Testing: The sample is tested at an NABL-accredited, ICMR-approved lab.

    • Receive Your Results: You’ll receive the test report via email or WhatsApp within 123 hours.

    The typical values for the Antimicrobial Antibody Test are as follows:

    • Negative: ≤20.0 units

    • Equivocal: 20.1-24.9 units

    • Positive: ≥25.0 units.

    You can typically expect the results of the Anti-Mitochondrial Antibody test within 123 hours after your sample is collected.

    The frequency of this test varies according to your doctor’s guidance. For patients diagnosed with PBC or other autoimmune liver diseases, it may be performed regularly to observe the disease's progression and response to treatment.

    The AMA test targets anti-mitochondrial antibodies in the blood, which are biomarkers for autoimmune liver diseases, notably PBC.

    Orange Health Labs offers home sample collection for the Anti-Mitochondrial Antibody (IFA) test across multiple localities in Gurgaon, including but not limited to Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56, DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, and DLF Phase 5. You can conveniently book the test and have your sample collected from the comfort of your home or office.

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    References

    1. Antimitochondrial Antibody and Antimitochondrial M2 Antibody - Health Encyclopedia - University of Rochester Medical Center.  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=antimitochondrial_antibody_m2
    2. Anti-mitochondrial antibody (AMA) [Internet]. South Tees Hospitals NHS Foundation Trust.  Available from:  https://www.southtees.nhs.uk/services/pathology/tests/anti-mitochondrial-antibody-ama/
    3. Antimitochondrial antibody: MedlinePlus Medical Encyclopedia [Internet].  Available from:  https://medlineplus.gov/ency/article/003529.htm
    4. Antimitochondrial antibody Information | Mount Sinai - New York.  Available from:  https://www.mountsinai.org/health-library/tests/antimitochondrial-antibody
    5. AMA: Mitochondrial Ab, McLendon Clinical Laboratories | UNC Medical Center, Hospitals – Chapel Hill, NC.  Available from:  https://www.uncmedicalcenter.org/mclendon-clinical-laboratories/available-tests/ama-mitochondrial-ab/