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    Cancer Antigen 125 (CA 125)2400160033% off
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    What Is Cancer Antigen 125 (CA 125) Test?

    The CA-125 test is a blood test that measures the level of Cancer Antigen 125, a protein that can be elevated in certain types of cancer, most notably ovarian cancer. The ovaries, which are female reproductive organs involved in egg storage and hormone production, produce CA-125. This protein is also produced by the cells lining other reproductive organs, such as the fallopian tubes and uterus. Elevated levels of CA-125 are not exclusive to cancer; they can also be seen in other health conditions.

    The CA-125 test is often used to screen postmenopausal women who are at high risk for ovarian cancer, especially those with a family history or genetic predisposition to the disease. Additionally, it is employed to evaluate individuals exhibiting symptoms that may indicate ovarian cancer. This test is crucial for monitoring the effectiveness of ovarian cancer treatment and for detecting cancer recurrence after treatment.

    For those in Delhi with risk factors or symptoms linked to ovarian cancer, a CA-125 test can be performed at home upon your doctor's recommendation to help monitor your health and assess your risk.

    Cancer Antigen 125 (CA 125) Test Parameters

    The Cancer Antigen 125 test focuses on a single parameter: measuring CA-125 protein levels in the bloodstream.

    CA-125 serves as a tumour marker and is produced by ovarian cancer cells, as well as the cells lining organs like the endometrium, fallopian tubes, lungs (pleura), gut (peritoneum), and heart (pericardium). This test is frequently used in serological testing when ovarian cancer is suspected and is vital for monitoring patients who have been diagnosed with epithelial ovarian cancers. CA-125 is believed to inhibit the immune system’s ability to target and remove diseased cells, including those that are cancerous or infected.

    Typically, CA-125 remains on the cell surface, protected by barriers that keep it from entering the bloodstream. When these barriers are compromised by cancerous cells, CA-125 leaks into the blood, leading to elevated levels that can be detected by tests. Furthermore, CA-125 is known to interact with other cellular proteins, potentially aiding in the growth and spread of cancer.

    Elevated CA-125 levels are most frequently seen in ovarian cancer, especially epithelial ovarian cancer, but can also be present in other types of cancer, such as those affecting the uterus, breast, and fallopian tubes. Increased levels of CA-125 may also occur in benign conditions, including ovarian cysts, fibroids, and endometriosis, as well as in normal physiological conditions like early pregnancy, the postpartum period, and menstruation.

    Cancer Antigen 125 (CA 125) Test Preparation

    Preparing for a Cancer Antigen 125 test at home is simple with these steps:

    Pre-requisites

    You do not need to fast before undergoing the CA-125 test.

    Best Time to Get Tested

    The CA-125 test can be taken at any time throughout the day.

    Who Should Get a Cancer Antigen 125 (CA-125) Test

    This CA-125 test is recommended for women who need to be diagnosed with ovarian cancer, especially those with symptoms or who have risk factors like a family history or genetic mutations. It’s also suitable for monitoring women already diagnosed with ovarian cancer who are undergoing treatment. Regular testing after treatment can help detect if the cancer has returned.

    Cautions Before Taking a Cancer Antigen 125 (CA-125) Test

    It’s important to be aware that CA-125 levels can be elevated due to non-cancerous conditions, such as pregnancy, menstruation, and fibroids. Talk to your doctor about any specific precautions to take before the test.

    Why Take the Cancer Antigen 125 (CA 125) Test?

    The CA-125 test is essential for managing ovarian cancer and assessing the risk of developing it. Here’s why this test might be necessary:

    • Evaluating Pelvic Lumps : If a suspicious lump is found in the pelvic region during imaging tests like an ultrasound, CA-125 levels can help assess whether the lump could indicate ovarian cancer.

    • Monitoring Treatment Progress : For those diagnosed with ovarian cancer, regular CA-125 tests during treatment help evaluate whether the therapy is effective. A decrease in CA-125 levels usually means that the treatment is working.

    • Checking for Recurrence : After treatment, CA-125 levels may be monitored every few months or annually to check for any signs of cancer recurrence.

    • High-Risk Individual Assessment

      • Individuals with a family history of ovarian, breast, or colorectal cancer.

      • Those with genetic mutations like BRCA1 or BRCA2.

      • People with hereditary conditions, such as Lynch syndrome, that raise the risk of various cancers.

      • Anyone with a history of ovarian, breast, colorectal, or uterine cancer.

    Because elevated CA-125 levels can occur in other conditions, this test is usually used in combination with other diagnostic tools to confirm a diagnosis.

    Cancer Antigen 125 (CA 125) Test Results and Interpretation

    The CA-125 test is a key tumour marker for assessing the treatment response and progress in patients with serous ovarian cancer. Below is a table that shows the normal CA-125 levels in the blood and the conditions that can cause elevated levels:

    TestBiological Reference (U/mL)Interpretation
    CA-125 (Serum)<35CA-125 is found in a high percentage of non-mucinous ovarian tumours of epithelial origin. Elevated levels are also found in ovarian cysts, endometriosis, cervicitis, cirrhosis, hepatitis, malignancy of endometrium, breast, or gastrointestinal tract.

    FAQs on Cancer Antigen 125 (CA 125) Test

    The cost of a Cancer Antigen 125 test in Delhi is 1600. This price is inclusive of rapid home sample collection from your desired location.

    Yes, Orange Health Labs provides home sample collection for the CA-125 test in Delhi. A skilled eMedic will arrive at your specified location within 60 minutes of booking, or at your preferred time, ensuring a hassle-free and convenient service.

    Primarily, the CA-125 test is used in the diagnosis, treatment, and ongoing monitoring of ovarian cancer. It is valuable for screening individuals at high risk or exhibiting symptoms of ovarian cancer. The test is most commonly employed during treatment to assess the therapy's effectiveness and to monitor for any recurrence of the cancer.

    No, fasting is not necessitated for a CA-125 test.

    Follow these instructions to book a blood test or health checkup on our platform:

    • Find the Test : Search for the CA-125 test in Delhi or at home and visit Orange Health’s page.

    • Review and Verify : Choose the test, check the prerequisites, enter your location, and complete your booking by selecting a time for sample collection.

    • Collection of Sample : At the scheduled time, an eMedic will come to your home to collect the sample.

    • Lab Processing : The sample will be sent to our ICMR-approved and NABL-accredited labs for processing.

    • Receive Results : Your results will be sent to you via email or WhatsApp within 71 hours, and they will also be accessible through our app.

    The normal level for the CA-125 test is <35 U/mL.

    Orange Health Labs offers a quick turnaround for the CA-125 test, with the report generally available within 71 hours after your sample is collected.

    The frequency of CA-125 tests varies depending on your health status. Those undergoing ovarian cancer treatment typically have the test done regularly to monitor therapy effectiveness and detect recurrence. If you’re at high risk or showing symptoms of ovarian cancer, your doctor may advise additional tests based on the results.

    The CA-125 test is designed to measure only one parameter: the amount of Cancer Antigen 125 (CA-125) protein present in the blood sample.

    The CA-125 test does not require fasting.

    With Orange Health, you can get the CA-125 test quickly and conveniently at home throughout Delhi, without needing to visit a physical lab. Our services cover multiple localities, including but not limited to Connaught Place, Chandni Chowk, Karol Bagh, Lajpat Nagar, South Extension, Greater Kailash, Hauz Khas, Saket, Vasant Kunj, Dwarka, Janakpuri, Rajouri Garden, Rohini, Pitampura, Mayur Vihar, Preet Vihar, Shahdara, Laxmi Nagar, Green Park, Safdarjung Enclave, Defence Colony, New Friends Colony, Kalkaji, Malviya Nagar, Nehru Place.

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    References

    1. CA-125 Blood Test (Ovarian Cancer) [Internet]. Medlineplus.gov. 2022 [cited 2024 Aug 2].  Available from:  http://medlineplus.gov
    2. CA-125 Blood Test: Results, Normal Range & What To Expect [Internet]. Cleveland Clinic. 2022 [cited 2024 Aug 2].  Available from:  https://my.clevelandclinic.org/health/diagnostics/17830-ca-125-blood-test
    3. Gandhi T, Zubair M, Bhatt H. Cancer Antigen 125 [Internet]. Nih.gov. StatPearls Publishing; 2024 [cited 2024 Aug 2].  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK562245/