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    What is Gamma Glutamyl Transferase (GGT) Test?

    The gamma-glutamyl transferase (GGT) test is a blood test used to measure the levels of GGT, an enzyme primarily found in the liver. Enzymes are proteins that facilitate essential chemical reactions within the body. While GGT is present in various tissues, it is most concentrated in the liver, which plays a critical role in protecting cells from damage.

    This test is commonly employed to assess liver health and identify potential damage or blockages in the bile ducts. Bile ducts are vital for carrying bile, a fluid produced by the liver that aids in digestion, in and out of the liver. Elevated GGT levels in the bloodstream often indicate liver disease, bile duct obstruction, or damage caused by factors such as alcohol, certain medications, or other health conditions affecting the liver, pancreas, or heart. A GGT test is frequently conducted alongside other liver function tests, particularly the alkaline phosphatase (ALP) test.

    Individuals concerned about assessing their liver health can also schedule a Gamma Glutamyl Transferase (GGT) test at home. Orange Health Labs offers convenient home-based testing for Gamma Glutamyl Transferase (GGT) test in Bangalore.

    Gamma Glutamyl Transferase (GGT) Test Parameters

    The GGT test measures a single parameter: GGT levels in the blood. This enzyme is a well-established marker for liver dysfunction and an indicator of alcohol use disorder. Beyond its diagnostic applications, GGT plays a vital physiological role in protecting your body from damage caused by harmful substances called free radicals. It does this by breaking down a compound called glutathione and providing its building blocks to your cells.

    High GGT levels are usually a sign of damaged bile ducts (tubes in the liver that carry bile) or liver abnormalities in the body. They can be observed in conditions like liver disease, heavy alcohol use, or certain medications. These situations can increase free radicals in your body and reduce your supply of glutathione, which is needed to fight these harmful substances. Thus, GGT serves as a valuable marker for understanding overall health risks.

    Gamma Glutamyl Transferase (GGT) Test Preparation

    Here is how individuals undergoing the GGT test at home can prepare themselves before the test:

    • Prerequisites

    No specific preparations such as fasting are required for the GGT test.

    • Best Time to Get Tested

    The GGT test can be done at any time of the day at your convenience.

    • Who Should Get a GGT Test

    The GGT test is recommended for individuals experiencing symptoms of liver disease, such as jaundice (yellowing of the skin and eyes), abdominal pain, or unexplained fatigue. It is also useful for those with a history of heavy alcohol use or taking medications that may impact liver function. 2 Additionally, individuals with ongoing liver disease or medical conditions like diabetes or heart disease that can affect liver health should consider getting this test to monitor liver function.

    • Cautions Before Taking a GGT Test

    Alcohol consumption and certain medications can significantly affect GGT levels, so it’s best to avoid alcohol for 24 hours before the test and inform your doctor about any medications you are taking. Certain medications like acetaminophen, phenytoin, and phenobarbital may increase GGT levels, whereas birth control pills and clofibrate may decrease GGT levels. 5 If you have been recently ill or have had surgery, it’s important to discuss this with your doctor as it may influence the results.

    Why Take the Gamma Glutamyl Transferase (GGT) Test?

    The GGT test is essential for assessing liver function and detecting various liver-related conditions. It helps in evaluating the functioning of the liver and bile ducts. The test is useful in the following instances:

    • Diagnosing liver disease and identifying potential liver damage.

    • Checking for blockages in the bile ducts.

    • Monitoring or screening for alcohol use disorder (AUD), as alcohol consumption increases GGT levels.

    • Determining if elevated GGT levels are related to liver issues or a bone disorder.

    • Investigating symptoms such as fatigue, jaundice (yellowing of the skin and eyes), abdominal pain, nausea, and severe itching.

    • Following up on abnormal results from other liver function tests like ALP to further understand liver or bile duct issues.

    FAQs on Gamma Glutamyl Transferase (GGT) Test in Bangalore

    The cost of a Gamma Glutamyl Transferase (GGT) Test in Bangalore is ₹230. This pricing includes home sample collection, which will occur within 60 minutes of your booking.

    Yes, Orange Health Labs provides home sample collection for the GGT test. After booking the test, an eMedic will arrive at your location within 60 minutes to collect the sample.

    A Gamma Glutamyl Transferase (GGT) test is used to evaluate liver function, diagnose liver disease, check for bile duct obstructions, and monitor alcohol use disorder. It can also help distinguish whether liver damage is due to bone-related health issues or liver disease.

    Fasting is generally not required for the Gamma Glutamyl Transferase (GGT) test.

    To book a Gamma Glutamyl Transferase (GGT) test with Orange Health Labs, follow these simple steps:

    • Search for the Test : Search for “Gamma Glutamyl Transferase (GGT) test at home.” Choose the Orange Health website from the listing.

    • Review and Verify : Select the test, check for any prerequisites, and enter your location details. Then, choose a suitable time for sample collection.

    • Sample Collection : A trained eMedic will come to collect your sample from your home at the scheduled time.

    • Laboratory Processing : The blood sample will be analysed in our ICMR-approved and NABL-accredited laboratory.

    • Receive Results : The test results will be delivered to you via email or WhatsApp within 6 hours, and can also be accessed via the Orange Health app.

    Normal GGT levels typically range from 15-73 IU/L for adults, although this can vary depending on age, gender, and the lab’s reference range. Elevated levels may indicate liver damage, bile duct obstructions, or excessive alcohol use.

    After booking the GGT test, an eMedic will collect your sample within 60 minutes. You can expect to receive your results within 6 hours after the sample collection.

    The frequency of the Gamma Glutamyl Transferase (GGT) test depends on your health status. It may be recommended annually for those at risk of liver disease or alcohol use disorder. For ongoing conditions, it may be done more frequently as per your doctor’s advice.

    The Gamma Glutamyl Transferase (GGT) test measures only one parameter, the concentration of GGT enzyme in the blood.

    You can get a Gamma Glutamyl Transferase (GGT) test done with the added convenience of home sample collection at multiple locations in Bangalore, including major localities like Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Domlur, Electronic City, Frazer Town, Giri Nagar, Hebbal, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. Gamma-glutamyl Transferase (GGT) Test [Internet]. 2. ‌Gamma-glutamyl transferase (GGT) Blood Test. [Internet]. Cleveland Clinic.  Available from:  https://medlineplus.gov/lab-tests/gamma-glutamyl-transferase-ggt-test/
    2. ‌3. Whitfield JB. Gamma Glutamyl Transferase. Critical Reviews in Clinical Laboratory Sciences [Internet].  Available from:  https://pubmed.ncbi.nlm.nih.gov/11563810/
    3. ‌Gamma-glutamyl transpeptidase (GGT) blood test Information | Mount Sinai - New York [Internet].  Available from:  https://www.mountsinai.org/health-library/tests/gamma-glutamyl-transpeptidase-ggt-blood-test
    4. ‌ 5. Gamma-Glutamyl Transpeptidase - Health Encyclopedia - University of Rochester Medical Center [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=gamma_glutamyl_transpeptidase