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    What is Calcium Creatinine Ratio, Urine Test?

    The Calcium-Creatinine Ratio test is a diagnostic urine test used to measure the levels of calcium and creatinine excreted in urine. 1 Creatinine is a substance produced during normal muscle metabolism. The test compares calcium levels to creatinine to provide an accurate assessment. It is primarily used to assess calcium metabolism and identify conditions that may lead to abnormalities like hypercalciuria (excess calcium in the urine) or hypocalciuria (low calcium in the urine). This test is a reliable method for evaluating kidney function and monitoring calcium balance in the body.

    The test is used to diagnose various disorders associated with impaired calcium metabolism or calcium imbalance. Excessive calcium excretion can be indicative of conditions such as kidney stones, hyperparathyroidism (overactive parathyroid function), or certain genetic disorders affecting calcium metabolism such as familial hypocalciuric hypercalcemia (FHH). Conversely, reduced calcium levels in the urine may suggest conditions like hypoparathyroidism or vitamin D deficiency. Studies suggest that the test may also be useful in detecting preeclampsia (high blood pressure during pregnancy).

    This test is particularly useful in children suspected of having hypercalciuria or other metabolic disorders, as it provides a non-invasive method to monitor calcium levels. It may also be recommended for adults experiencing recurrent kidney stones or those with a family history of calcium-related metabolic issues.

    If you're in Bangalore and need to schedule a Calcium-Creatinine Ratio test at home, consult your doctor to determine if the test is appropriate for you.

    Calcium Creatinine Ratio, Urine Test Parameters

    The Calcium-Creatinine Ratio test primarily evaluates three parameters, the concentration of calcium and creatinine levels in the urine sample, and their ratio.

    Calcium Levels in Urine: This parameter measures the amount of calcium excreted, which can indicate hypercalciuria if abnormally high or hypocalciuria if too low.

    Creatinine Levels in Urine: Creatinine is a byproduct of muscle metabolism produced in the body and excreted in the urine. It serves as a reference point to measure calcium excretion. Elevated creatinine levels without proportional calcium increases may indicate reduced kidney filtration or other metabolic abnormalities.

    Calcium Creatinine Ratio: The ratio is calculated by dividing the urinary calcium concentration (mg/dL) by the urinary creatinine concentration (mg/dL). This ratio provides a normalised value that reflects calcium excretion relative to kidney function.

    A ratio exceeding the normal range often points to conditions like hyperparathyroidism, kidney stones, or excessive dietary calcium intake. Lower ratios may suggest impaired calcium absorption or deficiencies in parathyroid function.

    Calcium Creatinine Ratio, Urine Test Preparation

    The Calcium Creatinine Ratio test at home can be conducted hassle-free with these steps:

    • Prerequisites

    Fasting is generally not required unless instructed by your doctor.

    • Best Time to Get Tested

    The test is typically done using a random urine sample so it can be scheduled at any time during the day.

    • Who Should Get a Calcium Creatinine Ratio Test?

    Individuals with recurrent kidney stones, signs of metabolic disorders, or suspected calcium metabolism issues may benefit from this test. It is also recommended for those with a family history of hypercalciuria, hyperparathyroidism, or related conditions.

    • Cautions Before Taking a Calcium Creatinine Ratio Test

    Before the test, inform your doctor if you are taking any medicines or supplements that may affect calcium or creatinine levels.

    Why Take the Calcium Creatinine Ratio, Urine Test?

    The Calcium-Creatinine Ratio test plays a crucial role in identifying and managing conditions related to calcium metabolism. Here are key reasons to get tested:

    • To Detect Kidney Stones

    The test helps identify excess calcium excretion, a major cause of calcium-based kidney stones. It is useful if you experience symptoms such as sharp abdominal pain, blood in the urine, or frequent urination.

    • To Monitor Kidney Health

    It evaluates how well your kidneys filter calcium, which can help diagnose kidney-related disorders. Abnormal results may indicate kidney damage or impaired calcium regulation.

    • To Evaluate Parathyroid Disorders

    Abnormalities in parathyroid hormone (PTH) can lead to calcium imbalances. This test helps assess conditions like hyperparathyroidism or hypoparathyroidism and their severity.

    • To Identify Bone Health Issues

    The test supports the diagnosis of bone conditions like osteoporosis by identifying abnormal calcium metabolism. It is particularly useful if calcium blood tests show irregularities.

    • To Diagnose Genetic Disorders

    Conditions like FHH affect calcium excretion. The test helps screen FHH and also differentiate between genetic causes and other metabolic issues.

    FAQs on Calcium Creatinine Ratio, Urine Test in Bangalore

    The cost of the Calcium Creatinine Ratio test in Bangalore is ₹500. This includes home sample collection within 60 minutes after booking.

    Yes, home sample collection is available for the Calcium Creatinine Ratio test with Orange Health Labs.

    The Calcium Creatinine Ratio test helps assess the levels of calcium in your urine, which is important for diagnosing disorders related to calcium metabolism, such as kidney stones, parathyroid disorders, bone health issues, and genetic conditions affecting calcium balance.

    No, fasting is not required for the Calcium Creatinine Ratio test. However, it is advisable to consult a doctor if you are undergoing other tests simultaneously.

    To book the Calcium Creatinine Ratio test at home, follow these steps:

    • Search the test: Search for "Calcium Creatinine Ratio test in Bangalore" or "Calcium Creatinine Ratio test at home" and choose Orange Health Labs from the options.

    • Confirm the booking: Select the test, review prerequisites, enter your location, and schedule a sample collection.

    • Sample Collection: A certified eMedic will collect the sample at your preferred time.

    • Assessment of Sample: Your sample will be analysed at our ICMR-approved, NABL-accredited laboratory.

    • Delivery of Results: Results will be sent via email or WhatsApp within 6 hours of sample collection and can also be accessed via our app.

    The normal level for the Calcium Creatinine Ratio test is <0.2. Levels higher than this may indicate hypercalciuria, while lower levels may suggest hypocalciuria.

    Once booked, an eMedic will collect your sample within 60 minutes. The results will be available within 6 hours after sample collection.

    The frequency of testing depends on your doctor’s recommendations, which will vary based on your calcium metabolism, symptoms, and any underlying health conditions.

    The parameters included in the test are calcium and creatinine levels in urine and calcium-to-creatinine ratio.

    Orange Health provides the Calcium Creatinine Ratio test across a wide range of areas in Bangalore, including but not limited to Yeshwantpur, Whitefield, Vijaya Nagar, Vidyaranyapura, Vasanth Nagar, Uttarahalli, Tyagarajnagar, Sri Nagar, Shivaji Nagar, Shanthi Nagar, Seshadripuram, Sarjapur, Sanjay Nagar, Sahakara Nagar, Sadashivnagar, Rajarajeshwari Nagar, Rajaji Nagar, RT Nagar, Peenya, Old Airport Road, Nandhini Layout, Nagarbhavi, Mysore Road, Mathikere, Marathahalli, Malleshwaram, Magadi Road, Madiwala, Mahalakshmi Layout, Koramangala, Kengeri, Kammanahalli, Kadugodi, Jalahalli, Jakkur, HSR Layout, Hosur, Hennur, Domlur, Hebbal, Giri Nagar, Frazer Town, CV Raman Nagar, Cottonpet, Chamrajpet, BTM Layout, Bellandur, Basavanagudi, Bannerghatta, Banashankari, and Adugodi.

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    References

    1. Foley KF, Boccuzzi L. Urine Calcium: Laboratory Measurement and Clinical Utility. Laboratory Medicine [Internet]. 2. Choi IS, Jung ES, Choi YE, Cho YK, Yang EM, Kim CJ. Random Urinary Calcium/Creatinine Ratio for Screening Hypercalciuria in Children with Hematuria. Annals of Laboratory Medicine [Internet]. 3. Creatinine [Internet]. National Kidney Foundation.  Available from:  https://academic.oup.com/labmed/article-abstract/41/11/683/2504912?redirectedFrom=fulltext
    2. Rodriguez MHellen, Masaki DI, Mestman J, Kumar D, Rude R. Calcium/creatinine ratio and microalbuminuria in the prediction of preeclampsia. 5. Wills MR. The urinary calcium/creatinine ratio is a measure of urinary calcium excretion. Journal of Clinical Pathology.  Available from:  https://pubmed.ncbi.nlm.nih.gov/3061296/
    3. Calcium in Urine Test [Internet].  Available from:  https://medlineplus.gov/lab-tests/calcium-in-urine-test/