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    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA2924262510% off
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    What is Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is a blood test that detects proteins produced by the immune system. While these proteins normally fight germs, in some cases, they mistakenly attack healthy neutrophils and monocytes, types of white blood cell.

    This test helps diagnose ANCA-associated vasculitis, an inflammation of blood vessels that can narrow, block, or weaken them, affecting organs like the kidneys, lungs, skin, and eyes. Early symptoms of vasculitis include fatigue, fever, weight loss, and body aches; however, if left untreated, it may cause serious organ damage.

    Two key proteins are linked to ANCA-associated vasculitis:

    • Myeloperoxidase (MPO) – Common in microscopic polyangiitis (MPA), affecting small blood vessels.

    • Proteinase 3 (PR3) – Often found in granulomatosis with polyangiitis (GPA), which involves the lungs and sinuses.

    Additional tests, such as PR3 ANCA, kidney function tests, inflammation markers, and full blood counts, help confirm diagnosis and monitor treatment.

    For individuals residing in Bangalore, getting an ANCA test at home can be convenient with prompt sample collection and delivery of results.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Parameters

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test measures a single parameter: the presence of autoantibodies in the blood, specifically PR3 and MPO.

    These autoantibodies specifically target two proteins:

    cANCA (cytoplasmic ANCA)

    Targets a protein called PR3. PR3 helps regulate blood cell production and can trigger programmed cell death.

    pANCA (perinuclear ANCA)

    Targets a protein called MPO. MPO is essential for fighting infections.

    When ANCAs are present, they activate neutrophils, causing them to release chemicals that trigger inflammation, swelling, and blood vessel damage, affecting organs like the lungs, kidneys, and skin. As neutrophils move through blood vessel walls, they release more chemicals, worsening the inflammation and tissue damage.

    Although ANCA, PR3, and MPO levels fluctuate, individuals with these autoantibodies can continue producing them even when they are undetectable. A positive ANCA test is commonly linked to vasculitis, but it can also occur in rheumatoid arthritis, inflammatory bowel disease, certain medications, and infections like endocarditis or respiratory infections.

    Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test Preparation

    To get ready for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test at home, you may review the following testing preparations:

    • Prerequisites : There are no prerequisites for the ANCA test, and fasting is not required before the test.

    • Best Time to Get Tested : You can schedule the ANCA test at any convenient time of the day.

    • Who Should Get an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test? : Anyone with unexplained fatigue, fever, weight loss, joint pain, or symptoms affecting the lungs, kidneys, skin, or nervous system should consider an ANCA test to check for autoimmune vasculitis.

    • Cautions Before Taking an Anti Neutrophil Cytoplasmic Antibody (ANCA) Test : There are no specific precautions required for the ANCA test.

    Why Take the Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test?

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is recommended if you have:

    • Unexplained symptoms: Fatigue, fever, weight loss, muscle/joint pain, or night sweats.

    • Organ-specific issues:

      • Eyes, ears, nose: Vision changes, sinus infections, or hearing loss.

      • Skin: Rashes, bruising, or itching.

      • Lungs: Coughing up blood or shortness of breath.

      • Kidneys: Blood or protein in the urine.

      • Nervous system: Tingling, numbness, or shooting pains.

      • Stomach and intestines: Vomiting blood, diarrhoea, or abdominal pain.

    • Suspected vasculitis conditions: Diseases like GPA or MPA.

    • Inflammatory bowel disease: Symptoms like diarrhoea, blood in the stool, or fever.

    • Ongoing monitoring: Regular tests to track known autoimmune vasculitis.

    The ANCA test plays a vital role in detecting, diagnosing, and monitoring vasculitis early, helping manage symptoms and preventing organ damage.

    FAQs on Anti Neutrophil Cytoplasmic antibody (ANCA) (IFA) with Reflex Testing for MPO & PR3 by EIA Test in Bangalore

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test in Bangalore costs ₹2625. This includes quick and convenient home sample collection within 60 minutes of booking. With Orange Health Labs, you’ll receive your test results within 43 hours of sample collection.

    Yes, Orange Health Labs provides a hassle-free home sample collection service for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test. A certified eMedic professional will visit your home within 60 minutes after booking to collect your blood sample.

    An Anti Neutrophil Cytoplasmic Antibody (ANCA) test helps detect autoimmune conditions like vasculitis by identifying specific autoantibodies in the blood, which can cause inflammation and damage to blood vessels and organs.

    No, fasting is not required for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test.

    Booking an Anti Neutrophil Cytoplasmic Antibody (ANCA) test with Orange Health Labs is simple:

    • Search for the Test : Look up "Anti Neutrophil Cytoplasmic Antibody (ANCA) test" and select the Orange Health Labs option from the search results.

    • Confirm Your Booking : Fill in your personal details, choose your location, and pick a time slot for sample collection that works best for you.

    • Sample Collection : A trained eMedic professional will visit your home or location to collect your blood sample.

    • Analysis and Results : The sample will be tested at our NABL-accredited, ICMR-approved laboratory, and the results will be sent to you via email or WhatsApp within 43 hours after sample collection.

    A normal ANCA test result is negative, indicating no p-ANCA or c-ANCA autoantibodies, which typically rules out autoimmune vasculitis. A positive result suggests abnormal levels and requires further evaluation for autoimmune conditions.

    The results for the Anti Neutrophil Cytoplasmic Antibody (ANCA) test are generally available within 43 hours after the sample has been collected.

    The frequency of taking the Anti Neutrophil Cytoplasmic Antibody (ANCA) test depends entirely on your specific medical condition and will be based on your doctor’s advice.

    The ANCA test measures antibodies like p-ANCA and c-ANCA, along with PR3 and MPO antibodies.

    The Anti Neutrophil Cytoplasmic Antibody (ANCA) test is accessible across several areas in Bangalore. These include but are not limited to Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Frazer Town, Giri Nagar, Hebbal, Domlur, Electronic City, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur.

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    References

    1. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: MedlinePlus Medical Test.  Available from:  https://medlineplus.gov/lab-tests/antineutrophil-cytoplasmic-antibodies-anca-test/
    2. Antineutrophil Cytoplasmic Antibodies (ANCA) Test: What It Is. 3. Antineutrophil cytoplasmic antibodies (ANCA) | Pathology Tests Explained. 4. Khalid N, Aeddula NR. Antinuclear Cytoplasmic Antibody [Internet]. PubMed. Treasure Island (FL). 5. The value of anti-neutrophil cytoplasmic antibodies (ANCA) testing for the diagnosis of ANCA-associated vasculitis, a systematic review and meta-analysis.  Available from:  https://my.clevelandclinic.org/health/diagnostics/22512-anca-test