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    What is a Pre-Chemotherapy Blood Checkup ?

    A Pre-Chemotherapy Blood Checkup involves a series of vital blood tests performed before beginning chemotherapy. These tests ensure your body is in the right condition to endure chemotherapy and its potential side effects. Since chemotherapy can influence various bodily functions, evaluating your health beforehand is essential.

    This checkup includes comprehensive tests to assess the condition of your blood, liver, kidneys, and clotting mechanisms. The blood analysis examines parameters such as red blood cells (RBCs), white blood cells (WBCs), and platelets, which are essential as chemotherapy can reduce their production by the bone marrow.

    Additionally, liver and kidney function tests are conducted because chemotherapy drugs can affect these organs. Tests like SGOT, SGPT, and bilirubin, along with kidney function tests and electrolytes, help determine if your body can process and eliminate the medications properly.

    The checkup also involves blood sugar levels and clotting time tests (prothrombin time) to provide a detailed overview of your health. Completing these evaluations before starting treatment helps your doctor personalise your chemotherapy plan, reducing risks and promoting the best outcomes for your health.

    Pre-Chemotherapy Blood Checkup Parameters

    Liver Function Test (LFT)

    Liver function is also called as liver profile or liver panel that measures different types of enzymes, proteins and other by products that are made by the liver. These tests analyses the levels of overall health of the liver. The liver performing its normal functions of producing protein and clearing bilirubin, a blood waste product.
    The liver panel test consists of:
    • Aspartate aminotransferase (AST): AST is an enzyme in your liver. High blood levels could be a sign of damage or disease.
    • Alanine aminotransferase (ALT): ALT is another enzyme that helps break down proteins and is found mainly in your liver. High levels in your blood could mean you have liver damage.
    • Alkaline phosphatase (ALP): ALP is an enzyme in your liver, bile ducts, and bones. You might have high values if you have liver damage or disease, and a blocked bile duct, or bone disease.
    • Bilirubin Total/Direct/ Indirect: Your body makes bilirubin when it breaks down red blood cells. Usually, your liver cleans up the bilirubin in your body. If you have high levels of a problem called jaundice, you may have liver damage.
    • Albumin: Albumin is a protein made by the liver that prevents the fluid from leaking out of the bloodstream.
    • Gamma-glutamyl transferase (GGT): High levels of the GGT enzyme could point to liver or bile duct damage.
    • Total protein: This analyses the sum of two kinds of protein in the blood known as albumin and globulin. The test may analyse the relative levels of albumin and globulin, which is reported as the A/G ratio.
    • Globulins: Globulins are a class of proteins in the blood.

    • Alkaline Phosphatase

    • SGOT / AST - Aspartate AminoTransferase

    • Alanine AminoTransferase/ ALT (SGPT)

    • Gamma-Glutamyl Transferase (GGT)

    • Total Bilirubin

    • Direct Bilirubin

    • Indirect Bilirubin

    • Total protein

    • ALBUMIN

    • Globulin

    • A:G ratio

    • SGOT/SGPT ratio

    Prothrombin Time (PT/INR)

    Blood clotting, or coagulation, is a necessary process which prevents a person from losing too much of blood if they are injured. However, sometimes clots formation can be dangerous, causing a serious problems like deep vein thrombosis (DVT) or pulmonary (lung) embolism. By evaluating the time, it takes your blood to clot via different methods, the PT tests help detect if you have a bleeding or clotting disorder. As per a pre-surgical test, the PT with INR test is performed that helps a doctor evaluate the likelihood of excessive bleeding or clotting to determine risks during or after surgery. This test is also clinically used to monitor individuals on a Warfarin (Coumadin®) anticoagulant (blood-thinner) therapy.

    Blood Sugar

    A Random blood sugar (RBS) test is one method for analysing the level of glucose or sugar circulating in the blood. This test can be done at any point in time. It is to check how well the blood glucose is been maintained.

    Kidney Function Test with Electrolytes (KFT / RFT)

    The Kidney/Renal (KFT/RFT) panel, also known as a kidney profile or kidney function test (KFT), is a group of tests that help in determining the health of the kidneys by evaluating various parameters, like proteins, electrolytes, minerals, and blood glucose.
    The most common components tested in most renal panels include:
    • Blood Urea/Blood Urea Nitrogen (BUN): The blood urea nitrogen test is derived from the blood urea. Sometimes it is also called urea. Blood urea is a waste product of protein activity. Like creatinine, it is removed from the blood by the kidneys and cleared from the body in the form of urine.
    • Creatinine: Creatinine is the by-product that is consistently formed as a result of normal muscle activity. The kidney removes creatinine from the blood so that it can be carried out of the body in the form of urine.
    • Calcium: Calcium is a mineral that is very vital for the bones, muscles, cardiovascular system, and nervous system. An excess of calcium makes the kidneys work harder to filter it.
    • Phosphorus: Phosphorus is a very essential mineral for the bones, teeth, nervous system, and muscles. Phosphorus is also needed to help balance and use other vitamins and minerals, including vitamin D, iodine, magnesium, and zinc. This phosphorus comes primarily from the foods and drinks that we consume.
    • Uric Acid: Uric Acid test is to analyse a nitrogenous compound that is produced by the metabolic breakdown of purine. Uric acid is also formed from the metabolic breakdown of the same types of food, like red meat, seafood, beans, etc.
    • Sodium: Sodium is an electrolyte that comes from the diet, and the levels of sodium (Na) in the body are mainly controlled by the kidneys.
    • Potassium: Potassium plays a key role in a number of bodily processes, including nerve transmission, heart contractility, cellular transport, and normal kidney function. Potassium is a type of electrolyte. Electrolytes are minerals that enable the acid-base balance, healthy fluid levels, and proper functioning of muscles and nerves. Potassium comes from the diet and is found throughout the body.
    • Chloride: Chloride is an electrolyte that works in conjunction with other electrolytes to carry out several functions, including preserving a healthy balance of fluids.

    • Urea

    • Blood Urea Nitrogen (BUN)

    • Uric acid

    • Phosphorus

    • Calcium

    • Creatinine

    • eGFR

    • Sodium

    • Potassium

    • Chloride

    • BUN Creatinine ratio

    Complete Blood Count (CBC) with ESR

    A Complete Blood Count (CBC) is a blood test used to examine your overall health and detect a wide range of disorders, including anemia, infection, and leukemia. Complete blood count test (CBC) measures several components of your blood including:
    • Red blood cells which helps to carry oxygen
    • White blood cells which helps to fight infection
    • Haemoglobin which carries oxygen in the red blood cells
    • Hematocrit (PCV) measures the proportion of red blood cells to the fluid component, or plasma, in your blood
    • Platelets which help with blood clotting
    An abnormal cell count may indicate that you have a medical condition that calls for further evaluation.

    • Red Blood Cell Count (RBC Count)

    • HEMATOCRIT

    • Haemoglobin (Hb)

    • Total WBC Count (TC)

    • MCV

    • MCH

    • MCHC

    • RDW

    • Absolute Neutrophil Count (ANC)

    • Absolute Lymphocyte Count (ALC)

    • Absolute Eosinophil Count (AEC)

    • Absolute monocyte count

    • absolute basophil count

    • platelets

    • neutrophil

    • Monocyte

    • Eosinophils

    • Basophils

    • mentzer index

    • Sehgal Index

    • platelet hematocrit

    • Erythrocyte Sedimentation Rate (ESR)

    • MPV

    • Neutrophil lymphocyte ratio

    • lymphocyte count

    Pre-Chemotherapy Blood Checkup Preparation

    Here are some important factors to keep in mind when planning a Pre-Chemotherapy Blood Checkup at home in Hyderabad:

    Prerequisites

    Fasting is not required for a Pre-Chemotherapy Blood Checkup.

    Best Time to Get Tested

    You can take a Pre-Chemotherapy Blood Checkup in Hyderabad at any time of the day.

    Who Should Get a Pre-Chemotherapy Blood Checkup

    This test is recommended for anyone preparing to start chemotherapy. It evaluates blood cell counts, as well as liver and kidney functions, to confirm readiness for treatment and to enable a tailored plan that minimises potential risks.

    Cautions Before Taking a Pre-Chemotherapy Blood Checkup

    No specific preparations are necessary to perform this checkup at home.

    Why Take the Pre-Chemotherapy Blood Checkup Checkup?

    A Pre-Chemotherapy Blood Checkup is vital to confirm your body is ready for the demands of chemotherapy. Before treatment begins, blood tests assess red blood cells (RBCs), white blood cells (WBCs), and platelets. Chemotherapy can suppress bone marrow, reducing blood cell levels. If your RBC count is too low, a transfusion may be required, while low WBC or platelet counts could make treatment unsafe.

    In addition to blood cells, these tests evaluate kidney and liver function, as these organs play a key role in processing chemotherapy drugs. Liver function is assessed through tests such as SGOT, SGPT, and bilirubin, while kidney health is monitored using urea, creatinine, and electrolytes. These results confirm that your body can handle and eliminate the medications effectively.

    The checkup also includes blood sugar and clotting time tests, providing your doctor with a comprehensive view of your health.

    By completing this checkup before treatment, any potential concerns can be identified and managed early. The results establish a health baseline, enabling doctors to track changes during treatment. If abnormalities are detected, your treatment plan may be delayed or modified to reduce risks. Regular monitoring ensures chemotherapy remains safe and tailored to your specific needs.

    FAQs on Pre-Chemotherapy Blood Checkup in Hyderabad

    The cost of the Pre-Chemotherapy Blood Checkup is ₹ 1999. This fee includes the fastest home sample collection service, completed within 60 minutes of booking.

    Yes, Orange Health Labs offers home sample collection for the Pre-Chemotherapy Blood Checkup, ensuring a convenient process. An eMedic will visit your home within 60 minutes of booking (subject to slot availability) or at your preferred time.

    This checkup assesses your overall health, including liver and kidney function, blood cell counts, and readiness for chemotherapy treatment.

    No fasting is required for the Pre-Chemotherapy Blood Checkup done at home.

    To book this test, follow these steps:

    • Search for the Test: Look up the Pre-Chemotherapy Blood Checkup and select Orange Health’s option.

    • Test Booking: Check the test details, confirm the requirements, add your address, and book your appointment by choosing a suitable sample collection time.

    • Sample Collection: An experienced eMedic will collect your sample at your preferred time slot from your home.

    • Laboratory Processing: The sample will be taken to our NABL-accredited and ICMR-approved lab for analysis.

    • Receive Results: Reports will be sent via email or WhatsApp within 3 hours and can also be accessed through our app.

    Normal levels for the tests in a Pre-Chemotherapy Blood Checkup may vary. Detailed reference ranges are available on our website.

    This checkup is quick, with sample collection taking only a few minutes. Reports are typically ready within 3 hours after the sample is collected.

    Your doctor will determine the frequency of the checkup based on your health condition and specific requirements.

    This checkup comprises five tests: CBC, Liver Function Tests, Kidney Function Tests, Blood Sugar, and Prothrombin Time, collectively evaluating 50 health parameters.

    Orange Health offers the fastest Pre-Chemotherapy Blood Checkup services in Hyderabad, conducted conveniently at your home without needing a physical laboratory visit. Localities served include but are not restricted to Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. Chambers P, Wei L, Forster MD, Kipps E, Wong ICK, Jani Y. Evidence to guide the optimal timing for pre‐chemotherapy blood tests for early breast, colorectal cancer and diffuse large B‐cell lymphoma. Cancer Medicine. 2021 Sep 28  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC8607255/
    2. Cancer Research UK. Chemotherapy tests | Cancer in general | Cancer Research UK [Internet].  Available from:  https://www.cancerresearchuk.org/about-cancer/treatment/chemotherapy/planning/chemotherapy-tests
    3. Warr J, Hird AE, DeAngelis C, Giotis A, Ko YJ. Baseline blood work before initiation of chemotherapy: what is safe in the real world? J Oncol Pract. 2013 Sep.  Available from:  https://ascopubs.org/doi/abs/10.1200/JOP.2012.000719