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    Direct Coombs Test (DCT)104480023% off
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    What Is a Direct Coombs Test (DCT) Test?

    The Direct Coombs test, also called the direct antiglobulin test (DAT), is a medical test used to detect antibodies that bind to red blood cells (RBCs), causing them to break down (haemolysis). This test plays a vital role in diagnosing blood-related disorders, such as autoimmune haemolytic anaemia (AIHA).

    In AIHA, the immune system mistakenly attacks its own RBCs, leading to a drop in RBC count. Symptoms of AIHA include tiredness, pale skin, breathing difficulties, and jaundice (yellowing of the skin or eyes). The Direct Coombs test (DCT) helps determine if the immune system is the underlying cause.

    The test requires a blood sample. A positive result indicates the presence of antibodies on RBCs, which can occur in autoimmune haemolytic anaemia, certain medications, or autoimmune diseases like lupus.

    If you're in Bangalore, you can undergo a DCT test in the city to ensure early diagnosis and proper management of your condition.

    Direct Coombs Test (DCT) Test Parameters

    The Direct Coombs test checks a single parameter – whether antibodies are attached to red blood cells (RBCs). These antibodies can cause RBCs to break down too quickly, leading to conditions such as anaemia and jaundice (yellowing of the skin or eyes). To carry out the test, a blood sample is first processed to remove any unbound antibodies, and a special chemical is then added to detect antibodies bound to the RBCs. In autoimmune haemolytic anaemia, the amount of clumping indicates the severity of the condition. This test is essential for diagnosing and monitoring blood disorders by identifying if the immune system is attacking RBCs, ensuring that appropriate treatment is provided.

    Direct Coombs Test (DCT) Test Preparation

    When booking a Direct Coombs test at home, here are a few key things to consider: Prerequisites

    There is usually no need for fasting or special preparation before the Direct Coombs test.

    Best Time to Get Tested

    You can take the Direct Coombs test at any time throughout the day.

    Who Should Take a Direct Coombs Test

    The test is typically recommended if you have symptoms of anaemia or jaundice, or if a blood transfusion reaction is suspected.

    Cautions Before Taking the Direct Coombs Test

    No specific precautions are necessary before taking the Direct Coombs test.

    Why Take the Direct Coombs Test (DCT) Test?

    The Direct Coombs test is performed when doctors suspect that the body is producing antibodies against its own red blood cells (RBCs), leading to their destruction through haemolysis. This condition can result in anaemia, where there are insufficient healthy RBCs to carry oxygen throughout the body.

    This test is particularly useful for diagnosing autoimmune haemolytic anaemia (AIHA), a disorder where the immune system attacks its own RBCs. It works by detecting antibodies or other substances like complement proteins that are attached to the RBCs. A positive result indicates that these antibodies are causing the breakdown of RBCs.

    The Direct Coombs test is also necessary if a haemolytic transfusion reaction is suspected, where the body has an adverse reaction to transfused blood. In these cases, the test helps doctors detect the immune response, which can be dangerous and requires immediate treatment. The test is also used to diagnose erythroblastosis fetalis (haemolytic disease of the newborn, HDN), where a mother’s immune system produces antibodies against her baby’s RBCs, potentially leading to jaundice. The test helps doctors assess whether the baby requires treatment.

    Infections such as mononucleosis, syphilis, and mycoplasma, or certain medications, can also trigger the body to produce antibodies that attack RBCs. The Direct Coombs test helps identify these causes. In summary, the Direct Coombs test is a vital diagnostic tool for identifying and managing conditions in which the immune system wrongly targets RBCs.

    FAQs on the Direct Coombs Test (DCT) Test in Noida

    The rate for the Direct Coombs test in Bangalore is ₹800. This includes home sample collection at your convenience within 60 minutes of booking confirmation, with results provided within 6 hours after the sample is collected.

    Yes, Orange Health Labs offers home sample collection for the Direct Coombs test in Bangalore. Following booking confirmation, a trained eMedic will arrive to collect your sample within 60 minutes, based on availability of the chosen slot.

    The Direct Coombs test is designed to identify antibodies that are attached to RBCs, which can help diagnose conditions such as haemolytic anaemia, transfusion reactions, and some infections.

    Fasting is usually not required for the Direct Coombs test at home. Nonetheless, please follow your doctor’s recommendations if specific preparations are necessary.

    To book a Direct Coombs test with Orange Health Labs, follow these simple steps:

    • Search for the Test : Go to the Orange Health website and select the Direct Coombs test in Bangalore.

    • Confirm Your Booking : Select the test, review the guidelines, input your location, and set a time that works best for you.

    • Sample Collection : A trained eMedic will come to your home or chosen location to collect your sample.

    • Laboratory Processing : The blood sample will be processed at a laboratory approved by ICMR and accredited by NABL.

    • Receive Results : You’ll receive your results by email or WhatsApp within 6 hours of sample collection and can also access them via the Orange Health app.

    A negative result in the Direct Coombs test is considered normal, meaning no antibodies are bound to red blood cells (RBCs). A positive result indicates that antibodies are present.

    Once your booking for the Direct Coombs test is confirmed, an eMedic will arrive to collect your sample within 60 minutes. Results are typically ready online within 6 hours after the sample is collected.

    The frequency with which you should undergo the Direct Coombs test is based on your health condition and your doctor’s guidance. It is important to consult your doctor to figure out the optimal testing schedule.

    The Direct Coombs test assesses only one factor – whether antibodies are attached to red blood cells (RBCs), and the result is typically either positive or negative.

    Orange Health provides convenient home testing services for the Direct Coombs test in Bangalore, covering areas such as DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, DLF Phase 5, Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56.

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    References

    1. Coombs test: MedlinePlus Medical Encyclopedia.  Available from:  https://medlineplus.gov/ency/article/003344.htm
    2. Cleveland Clinic. Coombs Test: Purpose, Procedure & Result.  Available from:  https://my.clevelandclinic.org/health/diagnostics/22978-coombs-test
    3. Theis SR, Hashmi MF. Coombs Test.  Available from:  https://www.ncbi.nlm.nih.gov/sites/books/NBK547707/
    4. Barrett-Connor E. Anemia and infection. The American Journal of Medicine.  Available from:  https://www.amjmed.com/article/0002-9343(72)90073-3/abstract