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    What is a Dengue NS1 Antigen ELISA Test?

    The Dengue NS1 Antigen ELISA test identifies the non-structural protein 1 (NS1) of the dengue virus in blood. It focuses on specific antigens, which are foreign materials entering the body. This detection is effective during the acute phase, or the initial 7 days of dengue fever, promoting early diagnosis and medical care.

    Dengue fever is a mosquito-borne illness caused by one of four serotypes of the dengue virus, which belongs to the genus Flavivirus. When an infected mosquito bites, the virus enters the bloodstream and begins to replicate. This leads to the characteristic symptoms of dengue fever which are triggered by the virus and the immune system response. The Dengue NS1 test can detect the virus in blood within the first 7 days of symptom onset. Studies demonstrate that NS1 antigen levels in the blood are associated with the severity of the disease, with elevated levels seen in severe cases. Thus, the Dengue Antigen test provides crucial diagnostic information for dengue infections.

    If you are in Noida and have dengue fever symptoms, a Dengue Antigen test can be crucial. Book your Dengue Antigen test in Noida today to ascertain your dengue status if you suspect exposure to the virus.

    Dengue NS1 Antigen ELISA Test Parameters

    Dengue is spread by Aedes mosquito bites. When a mosquito bites a person with dengue and then bites a healthy person, it transmits the virus. The dengue virus can destroy blood components responsible for clotting and maintaining blood vessel structure. This damage, in combination with immune system chemicals, can cause blood to leak from vessels, leading to internal bleeding. Thus, if symptoms arise, prompt testing is needed.

    The Dengue NS1 Antigen test examines only a single parameter: the presence of the dengue NS1 protein, which is released into the blood after infection. This test uses a blood sample and special antibodies to detect the NS1 antigen. Antibodies are proteins generated by the immune system in response to antigens such as NS1. The detection of NS1 in the blood implies an acute dengue virus infection, but its absence does not rule out infection. Doctors may order additional tests to validate the diagnosis.

    Dengue NS1 Antigen ELISA Test Preparation

    Consider the following before a Dengue Fever NS1 Antigen test:

    Prerequisites

    No fasting is necessary for the Dengue NS1 test.

    Best Time to Get Tested

    The Dengue Antigen test can be done at any time during the day.

    Eligibility for Dengue NS1 ELISA Test

    This test is suitable if you have been in a dengue-affected region and are experiencing symptoms like high fever, rash, muscle and joint pain, pain behind the eyes, nausea, or vomiting.

    Cautions Before Taking Dengue NS1 ELISA Test

    No special measures are needed before undergoing the Dengue NS1 test.

    Why Take a Dengue NS1 Antigen ELISA Test?

    If you have been in a dengue-endemic area and have begun to display symptoms of dengue fever, it is recommended to take a Dengue NS1 test. Symptoms typically appear within 4 to 10 days after being bitten by a mosquito and continue for 3 to 7 days. These symptoms generally include a sudden fever that can go up to 104°F or above, accompanied by any of the following:

    • Rash

    • Nausea

    • Vomiting

    • Headache

    • Severe pain behind the eyes

    • Muscle, bone, or joint pain

    Without timely treatment, some individuals may develop dengue haemorrhagic fever, a severe condition that results in nosebleeds, vomiting blood, blood in stools, bleeding gums, abdominal pain, frequent vomiting, and extreme fatigue. The risk of severe dengue highlights the importance of early detection and treatment.

    The NS1 antigen is detectable in the blood during the acute phase, so the NS1 test is performed within the first 7 days of symptoms. After this period, the test may become less sensitive.

    Thus, the Dengue Antigen test helps doctors in the early detection of dengue, confirming the infection, and ruling out other similar illnesses.

    The table below highlights how to interpret the findings of a Dengue NS1 ELISA test:

    NS1 ResultsIndex ValuesInterpretation
    Negative≤0.8Retest if NS1 antigen is not found. Further assessment is needed if symptoms persist.
    Equivocal0.8 to 1.1Should undergo testing using an alternative method.
    Positive≥1.1Indicates a dengue virus infection.

    Note that interference might occur if the blood sample contains antibodies against test components. For example, in dengue virus testing, cross-reactivity with other Flaviviruses or non-infectious conditions can lead to false positives or misinterpretation. Thus, it is essential to consider the patient's clinical history for accurate diagnosis. Utilising both NS1 detection and the IgM Antibody test can improve the accuracy of diagnosing dengue infection. The dengue NS1 ELISA is the preferred test within the first 7 days of symptoms. After 7-10 days, IgG and IgM antibody tests are recommended.

    FAQs on Dengue NS1 Antigen ELISA Test in Noida

    The Dengue NS1 Antigen ELISA test price is ₹600. Included in this cost is the quickest home sample collection, achievable within 60 minutes of booking, with reports ready in 44 hours.

    The Dengue NS1 Antigen test is designed to identify dengue infection within the first 7 days after the symptoms begin.

    No, fasting is not necessary for this test.

    Yes, Orange Health Labs offers home sample collection for the Dengue NS1 ELISA test. An eMedic will reach your location for sample collection within 60 minutes of booking the test (based on availability) or at your preferred date and time.

    Follow these steps to book any blood test or health checkup on our platform:

    • Find the Test : Search for the Dengue fever NS1 Antigen test in Noida or at home, then select Orange Health’s page.

    • Select and Confirm : Pick the test, review the prerequisites, provide your address details, and confirm the booking by selecting a suitable time slot for sample collection.

    • Sample Collection : Our skilled eMedic will visit your home within the chosen time slot to collect the sample.

    • Lab Examination : The collected sample will undergo examination at our NABL accredited and ICMR approved labs.

    • Receive Reports : You will receive your reports via email, WhatsApp, or our app within 44 hours of sample collection.

    Dengue NS1 ELISA test results are interpreted as follows:

    • Negative: Index values ≤0.8. If NS1 antigen is not found, it is recommended to retest.

    • Equivocal: Index values between 0.8 and 1.1. Further testing with another method is suggested.

    • Positive: Index values ≥1.1, indicating a dengue virus infection.

    The Orange Health Labs eMedic will reach your location within 60 minutes of scheduling your test. Sample collection usually takes less than 5 minutes, and you can expect to receive your results online in 44 hours.

    How often you should be tested depends on your doctor's guidance, which usually considers your symptoms, test results, and any existing health issues. Usually, this test is recommended only once in the initial stages of dengue infection.

    In the Dengue NS1 Antigen test, the sole parameter is detecting the NS1 protein, a marker released into the bloodstream during infection.

    The Dengue NS1, IgM, and IgG tests detect various components of the virus and the immune response to a dengue infection:

    • NS1 test: Identifies the NS1 protein, present in the blood during the early phase of infection, detectable from days 1 to 7 after symptoms start.

    • IgM test: Identifies IgM antibodies, which become evident from days 3 to 5 of infection and last for 2 to 3 months.

    • IgG test: Identifies IgG antibodies, which usually appear by day 14 of infection and persist for life.

    The results from these antigen and antibody tests are correlated to confirm an ongoing dengue virus infection.

    Yes, for certain individuals, NS1 can still be found in the blood a few days beyond the acute phase of infection.

    Even though a positive NS1 test indicates dengue infection, it does not reveal the serotype of the virus. Serotype identification requires nucleic acid amplification tests (NAAT), like real-time reverse transcriptase-polymerase chain reaction (RT-PCR), which detect the genetic material of the dengue virus.

    Having a negative NS1 test result after exposure to the virus does not definitively rule out dengue infection. To confirm the diagnosis, your doctor may recommend additional tests like NAAT (RT-PCR) or an IgM antibody test.

    Without having to visit a physical lab, Orange Health provides the fastest Dengue Fever NS1 Antigen test services near you across Noida at the convenience of your home. Localities include but not limited to Sector 1, Sector 15, Sector 18, Sector 26, Sector 37, Sector 50, Sector 62, Sector 76, Sector 93, Sector 100, Sector 104, Sector 110, Sector 120, Sector 128, Sector 137, Sector 150, Sector 168, Sector 71, Sector 63, Sector 22, Sector 41, Sector 108, Sector 47, Sector 121, Sector 45.

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