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    Cancer Antigen 125 (CA 125)2400160033% off
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    What Is Cancer Antigen 125 (CA 125) Test?

    The Cancer Antigen 125 (CA-125) test is a blood test that measures the amount of CA-125 protein, which can be elevated in various types of cancer, particularly ovarian cancer. The ovaries, the female reproductive organs responsible for egg storage and hormone production, produce CA-125, but this protein is also generated by the cells lining the fallopian tubes and uterus. High levels of CA-125 can be detected in several cancers as well as other medical conditions.

    The CA-125 test is commonly used for screening postmenopausal women at high risk for ovarian cancer, especially those with a strong family history or genetic predisposition. It is also used to evaluate individuals with symptoms that might suggest ovarian cancer. This test is especially helpful for monitoring the effectiveness of ovarian cancer treatments and checking for recurrence after treatment.

    If you are living in Noida and have risk factors or symptoms associated with ovarian cancer, you might consider having a CA-125 test done at home with your doctor's advice to keep track of your health and assess your risk.

    Cancer Antigen 125 (CA 125) Test Parameters

    The CA-125 test has a single parameter: measuring the level of CA-125 protein in the bloodstream.

    CA-125 is a tumour marker produced by ovarian cancer cells and the cells lining organs such as the endometrium, fallopian tubes, lungs (pleura), gut (peritoneum), and heart (pericardium). This test is particularly useful in serological tests for suspected ovarian cancer and for monitoring patients diagnosed with epithelial ovarian cancers. CA-125 is considered to play a role in suppressing the immune system's ability to eliminate diseased cells, including cancerous and infected cells.

    Normally, CA-125 remains on the cell surface, as there are protective barriers that prevent it from entering the bloodstream. However, when these barriers are disrupted by cancerous cells, CA-125 leaks into the blood, leading to elevated levels detectable by the test. Additionally, CA-125 may interact with other proteins in cells to promote the growth and spread of cancer.

    Elevated CA-125 levels are commonly seen in ovarian cancer, particularly epithelial ovarian cancer, but can also be elevated in other cancers, such as those affecting the uterus, breast, and fallopian tubes. Non-cancerous conditions like ovarian cysts, fibroids, and endometriosis can also cause elevated CA-125 levels, as can normal physiological states such as the first trimester of pregnancy, the postpartum period, and menstruation.

    Cancer Antigen 125 (CA 125) Test Preparation

    The below steps will help you prepare for a Cancer Antigen 125 test at home:

    Pre-requisites

    No fasting is required before the CA-125 test.

    Best Time to Get Tested

    The CA-125 test can be performed at any time of the day.

    Who Should Get a Cancer Antigen 125 (CA-125) Test

    The CA-125 test is advisable for women who need to diagnose ovarian cancer, particularly those with symptoms or who have risk factors like a family history or genetic mutations. It is also recommended for monitoring women already diagnosed with ovarian cancer who are currently undergoing treatment. After treatment, regular testing can help check for any recurrence of the cancer.

    Cautions Before Taking a Cancer Antigen 125 (CA-125) Test

    Remember that elevated CA-125 levels can occur due to non-cancerous conditions such as pregnancy, menstruation, and fibroids. Consult with your doctor about any necessary precautions before taking the test.

    Why Take the Cancer Antigen 125 (CA 125) Test?

    The CA-125 test plays a significant role in ovarian cancer management and risk evaluation. Here’s when this test might be needed:

    • High-Risk Assessment

      • Individuals with a family history of ovarian, breast, or colorectal cancer.

      • People with genetic mutations like BRCA1 or BRCA2.

      • Those with hereditary conditions like Lynch syndrome that increase the risk of multiple cancers.

      • Individuals with a history of ovarian, breast, colorectal, or uterine cancer.

    • Monitoring Treatment : If you have ovarian cancer, regular CA-125 tests during treatment help determine if the therapy is effective. A reduction in CA-125 levels typically signals that the treatment is working.

    • Checking for Recurrence : After completing cancer treatment, periodic CA-125 testing every few months or annually can help detect any recurrence of the cancer.

    • Evaluating Pelvic Lumps : When a suspicious lump is identified in the pelvic area through imaging tests like ultrasound, CA-125 levels can help decide if the lump might be ovarian cancer.

    Given that elevated CA-125 levels can also be present in other conditions, the test is often paired with other diagnostic tools to confirm a diagnosis.

    Cancer Antigen 125 (CA 125) Test Results and Interpretation

    CA-125 is utilised as a tumour marker to monitor therapy and track progress in patients with serous ovarian cancer. The table below indicates the normal CA-125 levels in the blood and the conditions that result in higher levels:

    TestBiological Reference (U/mL)Interpretation
    CA-125 (Serum)<35CA-125 is found in a high percentage of non-mucinous ovarian tumours of epithelial origin. Elevated levels are also found in ovarian cysts, endometriosis, cervicitis, cirrhosis, hepatitis, malignancy of endometrium, breast, or gastrointestinal tract.

    FAQs on Cancer Antigen 125 (CA 125) Test

    The cost of a Cancer Antigen 125 test in Noida is 1600. This cost covers fast home sample collection from your desired location.

    Yes, Orange Health Labs indeed offers home sample collection services for the CA-125 test in Noida. A professional eMedic will come to your location within 60 minutes of booking, or at a time that works best for you, providing a convenient and smooth experience.

    The CA-125 test is mainly applied in diagnosing, treating, and monitoring ovarian cancer. It helps in screening those at high risk or with symptoms suggestive of ovarian cancer. The test is most frequently used during treatment to determine the effectiveness of the therapy and to detect any recurrence of the disease.

    No, fasting is not necessary for a CA-125 test.

    To book a blood test or health checkup through our platform, follow these steps:

    • Find the Test : Look for the CA-125 test in Noida or at home and access Orange Health’s page.

    • Review and Verify : Select the test, check the prerequisites, enter your location, and complete your booking by choosing a suitable time for sample collection.

    • Collection of Sample : At the scheduled time, an eMedic will arrive at your home to collect the sample.

    • Lab Processing : The collected sample will be forwarded to our ICMR-approved and NABL-accredited labs for testing.

    • Receive Results : Your results will be delivered via email or WhatsApp within 80 hours and can also be viewed on our app.

    The normal level for the CA-125 test is <35 U/mL.

    You can rely on a rapid turnaround time for the CA-125 test at Orange Health Labs, with results typically delivered within 80 hours following sample collection.

    How frequently CA-125 tests are done depends on your health condition. For individuals receiving ovarian cancer treatment, the test is administered regularly to assess how well the therapy is working and to check for recurrence. For high-risk individuals or those with symptoms, your doctor may recommend further testing depending on the results.

    The CA-125 test specifically measures one parameter: the level of Cancer Antigen 125 (CA-125) protein in the blood sample.

    The CA-125 test does not require fasting.

    Orange Health offers rapid CA-125 test services right at your doorstep throughout Noida, eliminating the need for a physical lab visit. Services are available in various localities, including but not limited to Sector 1, Sector 15, Sector 18, Sector 22, Sector 26, Sector 37, Sector 41, Sector 45, Sector 47, Sector 50, Sector 62, Sector 63, Sector 71, Sector 76, Sector 93, Sector 100, Sector 104, Sector 108, Sector 110, Sector 120, Sector 121, Sector 128, Sector 137, Sector 150, Sector 168.

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    References

    1. CA-125 Blood Test (Ovarian Cancer) [Internet]. Medlineplus.gov. 2022 [cited 2024 Aug 2].  Available from:  http://medlineplus.gov
    2. CA-125 Blood Test: Results, Normal Range & What To Expect [Internet]. Cleveland Clinic. 2022 [cited 2024 Aug 2].  Available from:  https://my.clevelandclinic.org/health/diagnostics/17830-ca-125-blood-test
    3. Gandhi T, Zubair M, Bhatt H. Cancer Antigen 125 [Internet]. Nih.gov. StatPearls Publishing; 2024 [cited 2024 Aug 2].  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK562245/