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    What is Apolipoprotein A1 (Apo-A1) Test?

    The Apolipoprotein A1 (Apo A1) test evaluates the amount of apolipoprotein A1 in the blood, a protein vital for cholesterol transport. Apolipoproteins assist in forming lipoproteins, which move cholesterol through the body. Apo A1 is a major component of HDL, or "good cholesterol," which helps remove excess cholesterol from circulation, reducing the risk of arterial plaque buildup.

    A low Apo A1 level may suggest a deficiency in "good cholesterol" particles, potentially heightening the risk of cardiovascular disease and circulation issues. Physicians may recommend this test for individuals with high cholesterol, a family history of heart disease, or hyperlipidaemia. It also helps assess the impact of cholesterol-lowering treatments and lifestyle changes. Conditions such as diabetes, kidney disease, smoking, and certain medications can contribute to low Apo A1 levels, while elevated levels are generally not concerning and may be associated with exercise, weight loss, or pregnancy.

    Although not a routine test, the Apo A1 test provides additional details about heart health and is used alongside other cholesterol tests when needed.

    Apolipoprotein A1 (Apo-A1) Test Parameters

    The Apo A1 test quantifies Apo A1 levels in the blood, a protein that makes up approximately 65% of HDL. This protein is essential for HDL formation and supports lecithin cholesterol acyltransferase (LCAT), an enzyme responsible for modifying cholesterol into a form that can be eliminated from the body. HDL’s primary role is to transport excess cholesterol from the body’s tissues to the liver, where it is broken down and removed. Insufficient Apo A1 levels may impair this function, increasing the risk of cardiovascular diseases and vascular complications. People with hardened arteries (atherosclerosis) often have reduced Apo A1 levels. Although genetic factors influence Apo A1 levels, not all genetic variations contribute to heart problems. Apo A1 is frequently measured in combination with Apolipoprotein B (Apo B) to better evaluate heart disease risk. The relationship between these two proteins provides a more comprehensive heart health assessment than conventional cholesterol tests.

    Apolipoprotein A1 (Apo-A1) Test Preparation

    Here is how you can prepare for the Apolipoprotein A1 test at home:

    Prerequisites

    No dietary restrictions or special preparations are necessary before this test.

    Best Time to Get Tested

    The Apo A1 test can be taken at any time of the day.

    Who Should Get an Apolipoprotein A1 Test?

    Those with high cholesterol, a family history of heart disease, or individuals tracking their cholesterol due to treatment or lifestyle modifications should consider it.

    Cautions Before Taking Apolipoprotein A1 Test

    No particular precautions are needed before undergoing the test.

    Why Take the Apolipoprotein A1 (Apo-A1) Test?

    The Apolipoprotein A1 test should be conducted for the following reasons:

    • Individuals with a known history of high cholesterol or hyperlipidaemia

    • Assessing the Apo A1/Apo B ratio to gain a better understanding of cholesterol levels

    • Monitoring cholesterol improvement in response to treatment or lifestyle modifications

    • Identifying genetic conditions linked to reduced HDL cholesterol levels

    • Individuals with a family history of early cardiovascular disease or heart attacks

    More reliable than a standard HDL cholesterol test, the Apo A1 test provides a deeper evaluation of heart health and potential cardiovascular risks.

    FAQs on Apolipoprotein A1 (Apo-A1) Test in Noida

    The cost of an Apo A1 test in Noida is ₹650. The test includes a home sample collection, conducted within 60 minutes after booking confirmation. Results are typically available within 6 hours.

    Yes, Orange Health Labs provides home sample collection services for the Apo A1 test in Noida. A qualified eMedic will collect your sample within 60 minutes after booking, subject to availability.

    This test measures Apo A1, a protein in HDL cholesterol, which helps evaluate cardiovascular risk. It is particularly beneficial for individuals with high cholesterol or a family history of heart disease.

    Generally, fasting is not required for the Apo A1 test. However, if your doctor has given specific instructions, it’s important to follow them.

    Follow these simple steps to book an Apolipoprotein A1 test with Orange Health Labs in Noida:

    • Search for the test : Visit the Orange Health website and locate the Apolipoprotein A1 test in Noida.

    • Confirm the appointment : Choose the test, review the guidelines, provide your location, and select a preferred time slot.

    • Home sample collection : A qualified eMedic will visit your location to collect the blood sample after booking confirmation.

    • Lab processing : The sample is processed at an ICMR-approved and NABL-accredited laboratory.

    • Access your results : The test report will be delivered via email or WhatsApp within 6 hours and can also be accessed through the Orange Health app.

    Apolipoprotein A1 levels typically range from 105 mg/dL to 175 mg/dL.

    After booking confirmation, an eMedic will collect your sample within 60 minutes, and results will be ready within 6 hours.

    Testing intervals depend on your health needs and doctor’s advice. Speak with your physician to determine when to repeat the test.

    The test specifically measures Apolipoprotein A1, a critical protein component of HDL cholesterol.

    Orange Health provides home sample collection for this test in various Noida localities, including Sector 1, Sector 15, Sector 18, Sector 26, Sector 37, Sector 50, Sector 62, Sector 76, Sector 93, Sector 100, Sector 104, Sector 110, Sector 120, Sector 128, Sector 137, Sector 150, Sector 168, Sector 71, Sector 63, Sector 22, Sector 41, Sector 108, Sector 47, Sector 121, Sector 45.

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    References

    1. Apolipoprotein A-1 | Pathology Tests Explained [Internet].  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=Apolipoprotein+A-1
    2. Apolipoprotein A1 – Supra-Regional Assay Service [Internet].  Available from:  https://www.sas-centre.org/assays/cardiovascular-biomarkers/apolipoprotein-a1