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    What is Anti Gliadin Deamidated Peptide antibody IgA Test?

    The Gliadin Deamidated Peptide Antibody IgA test is a blood test which helps to detect coeliac disease and other autoimmune disorders triggered by gluten, including dermatitis herpetiformis (the skin-related form of coeliac disease). This test identifies IgA antibodies targeting deamidated gliadin peptides (DGP), a more precise and reliable marker for diagnosing coeliac disease compared to conventional gliadin antibody tests.

    Coeliac disease occurs when gluten consumption provokes an immune reaction that harms the small intestine, leading to problems like nutrient malabsorption, anaemia, and other long-term health complications. IgA antibody testing is considered critical for confirming the diagnosis and ensuring proper treatment.

    This test is helpful for identifying coeliac disease in symptomatic individuals and monitoring gluten-free diet compliance. Additionally, it serves as an essential tool for screening high-risk populations, such as those with close relatives diagnosed with coeliac disease.

    For individuals in Mumbai looking to evaluate gluten sensitivity or coeliac disease, booking a Gliadin Deamidated Peptide Antibody IgA test at home is an excellent option.

    Anti Gliadin Deamidated Peptide antibody IgA Test Parameters

    The Gliadin Deamidated Peptide Antibody (DGP) IgA test evaluates the presence of IgA antibodies that specifically target deamidated gliadin peptides (DGPs). These modified peptides derive from gliadin, a key component of gluten, found in commonly consumed grains such as wheat, rye, and barley. Elevated DGP antibody levels are a strong indicator of coeliac disease or related gluten-sensitivity autoimmune conditions, as they highlight the body’s immune response to gluten ingestion. 1,5

    Anti Gliadin Deamidated Peptide antibody IgA Test Preparation

    Getting ready for the Gliadin Deamidated Peptide Antibody IgA test is simple if you follow these guidelines:

    • Prerequisites

    Fasting is not necessary for this test. It is recommended to continue consuming gluten-containing foods for several weeks before testing to ensure accurate results.

    • Best Time to Get Tested

    The Gliadin Deamidated Peptide Antibody IgA test can be conveniently scheduled for any time of the day that fits your routine. 4

    • Who Should Get a Gliadin Deamidated Peptide Antibody IgA Test?

    This test is ideal for individuals showing symptoms like persistent diarrhoea, unexplained weight loss, or signs of malabsorption. It’s also valuable for patients following a gluten-free diet to track dietary adherence and for those with a family history of coeliac disease or related autoimmune conditions. 1

    • Cautions Before Taking a Gliadin Deamidated Peptide Antibody IgA Test

    Be sure to inform your doctor about any medications you are taking or existing health conditions that could potentially influence the test results.

    Why Take the Anti Gliadin Deamidated Peptide antibody IgA Test?

    The Gliadin Deamidated Peptide Antibody test plays a vital role in diagnosing coeliac disease. It helps assess the extent of intestinal injury, tracks dietary progress, and ensures compliance with a gluten-free lifestyle.

    You may require this test if you:

    • Suffer from chronic symptoms like constipation, bloating, vomiting, diarrhoea, gas, nausea, or unexplained weight loss.

    • Have non-digestive manifestations like headaches, depression, anxiety, fatigue, an itchy rash, or irritability in children.

    • Have a close family member with coeliac disease or autoimmune disorders, including type 1 diabetes.

    • Are already diagnosed with coeliac disease and need to confirm adherence to a gluten-free diet.

    • To detect coeliac disease early, even in the absence of symptoms but with known risk factors.

    Coeliac disease causes permanent damage to the small intestine, unlike gluten sensitivity or wheat allergies, making early diagnosis and lifelong dietary intervention essential.

    FAQs on Anti Gliadin Deamidated Peptide antibody IgA Test in Mumbai

    The Gliadin Deamidated Peptide Antibody IgA test in Mumbai costs ₹2165. It includes home sample collection within 60 minutes of booking. Test results will be shared within 99 hours after collection. 4

    Yes, Orange Health Labs offers quick home sample collection services in Mumbai. A trained eMedic will collect the sample within 60 minutes after test booking. 4

    This test is crucial for detecting and managing coeliac disease, a gluten-induced autoimmune condition. It measures IgA antibodies against DGP, reliable indicators for coeliac disease and dermatitis herpetiformis. Additionally, it is used to monitor gluten-free diet adherence in diagnosed individuals. 3

    Fasting is not required. You can continue consuming gluten-containing foods prior to testing unless your doctor recommends otherwise. 4

    To book the Gliadin Deamidated Peptide Antibody IgA test with Orange Health Labs, follow these steps:

    • Search for the Test: Visit the Orange Health Labs website or app to find the "Gliadin Deamidated Peptide Antibody IgA test."

    • Confirm Your Test Booking: Enter personal details, choose your location, and pick a convenient time for sample collection.

    • Sample Collection: A trained eMedic will visit your location at the scheduled time.

    • Laboratory Processing: Samples are analysed in an NABL-accredited and ICMR-approved laboratory.

    • Results Delivery: Reports will be shared via WhatsApp or email within 99 hours.

    The normal reference range for this test is <25 RU/mL. Levels exceeding this threshold may indicate coeliac disease or gluten sensitivity. However, the results should always be reviewed alongside other diagnostic findings by a doctor.

    The reports for this test are usually delivered within 99 hours after your sample has been collected. 4

    The frequency of testing depends on your doctor’s advice. It is commonly done for the initial diagnosis, ongoing monitoring of coeliac disease, or assessing adherence to a gluten-free diet. 1

    This test identifies IgA antibodies against deamidated gliadin peptides, which are critical markers for diagnosing gluten-sensitive enteropathies such as coeliac disease. 1,2

    Orange Health Labs offers home sample collection in all major localities in Mumbai, including Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Coeliac Disease Screening.  Available from:  https://medlineplus.gov/lab-tests/celiac-disease-screening/
    2. Gliadin, deamidated antibody, IgA | MLabs.  Available from:  https://mlabs.umich.edu/tests/gliadin-deamidated-antibody-iga
    3. Comparative Usefulness of Deamidated Gliadin Antibodies in the Diagnosis of Coeliac Disease. Clinical Gastroenterology and Hepatology.  Available from:  https://pubmed.ncbi.nlm.nih.gov/18304884/
    4. An overview, from primary structure to nanostructures of aggregates. Biophysical Reviews.  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC5899726/