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    What is Gamma Glutamyl Transferase (GGT) Test?

    The gamma-glutamyl transferase (GGT) test is a blood examination designed to measure GGT levels, an enzyme primarily found in the liver. Enzymes are proteins that drive vital chemical reactions in the body. Although GGT is present in several tissues, it is most abundant in the liver, where it plays a protective role for cells.

    This test helps assess liver function and detect abnormalities such as liver damage or bile duct blockages. Bile ducts are crucial for moving bile, a liver-produced fluid essential for digestion, in and out of the liver. Elevated GGT levels in the bloodstream may indicate liver disease, bile duct obstruction, or damage linked to alcohol use, certain drugs, or conditions affecting the liver, pancreas, or heart. GGT testing is often paired with other liver function tests, particularly the alkaline phosphatase (ALP) test.

    For individuals aiming to monitor their liver health, the Gamma Glutamyl Transferase (GGT) test can be done at home. Orange Health Labs offers hassle-free home-based GGT testing in Mumbai.

    Gamma Glutamyl Transferase (GGT) Test Parameters

    The GGT test focuses on measuring one parameter: GGT levels in the blood. This enzyme is a well-established marker for identifying liver dysfunction and alcohol use disorder. Beyond its diagnostic importance, GGT plays a crucial role in protecting the body from damage caused by free radicals—harmful substances that can damage cells. It does so by breaking down glutathione, a compound essential for neutralizing these harmful agents and making its components available to cells.

    Higher-than-normal GGT levels often indicate damage to the bile ducts (small channels in the liver that move bile) or other liver issues. Such elevations are commonly linked to liver diseases, prolonged alcohol use, or certain medications. These factors can raise the level of free radicals in the body while reducing glutathione availability, impairing the body’s defence against these substances. Thus, GGT serves as a valuable marker for assessing health risks.

    Gamma Glutamyl Transferase (GGT) Test Preparation

    Preparing for a GGT test at home is straightforward. Follow these guidelines for a smooth process:

    • Prerequisites The GGT test does not require any specific preparation, such as fasting.

    • Best Time to Get Tested You can take the GGT test at any time during the day, depending on your schedule.

    • Who Should Get a GGT Test The GGT test is recommended for people experiencing symptoms of liver disease, including jaundice, persistent tiredness, or abdominal pain. It is also beneficial for individuals with a history of heavy alcohol intake or those on medications that could affect liver function. Additionally, individuals managing chronic liver conditions or systemic illnesses like diabetes and heart disease that impact liver health should consider this test to track liver function.

    • Cautions Before Taking a GGT Test To ensure accurate results, avoid consuming alcohol for 24 hours prior to the test and disclose any medications you are using to your doctor. Some drugs, such as acetaminophen, phenytoin, and phenobarbital, may elevate GGT levels, while others like birth control pills and clofibrate might lower them. If you’ve recently been sick or undergone surgery, inform your doctor, as these factors could influence the results.

    Why Take the Gamma Glutamyl Transferase (GGT) Test?

    The GGT test is essential for evaluating liver function and diagnosing a range of liver-related issues. It is particularly valuable in examining the performance of the liver and bile ducts, and it proves beneficial in the following cases:

    • Detecting liver disease and identifying possible liver damage.

    • Determining the presence of blockages in the bile ducts.

    • Monitoring or screening for alcohol use disorder (AUD), as GGT levels often increase with alcohol consumption.

    • Understanding whether elevated GGT levels are due to liver problems or bone disorders.

    • Exploring symptoms like jaundice, fatigue, abdominal pain, nausea, or intense itching.

    • Conducting follow-up investigations on abnormal liver function tests, such as ALP, to pinpoint liver or bile duct issues.

    FAQs on Gamma Glutamyl Transferase (GGT) Test in Mumbai

    The cost for the GGT test in Mumbai is ₹230. This price covers home sample collection, scheduled within 60 minutes of booking.

    Yes, Orange Health Labs offers home sample collection for the GGT test. After booking, a trained eMedic will collect the sample at your location within 60 minutes.

    This test checks liver function, identifies liver diseases, diagnoses bile duct issues, and tracks alcohol use disorder. It also helps determine if liver damage relates to bone health problems.

    Fasting is not generally necessary before taking the GGT test.

    To book the test:

    • Search for the test online and choose Orange Health’s website.

    • Review details like prerequisites, provide location, and pick a convenient time slot.

    • Sample collection is done at home by an eMedic.

    • Processing occurs in an ICMR-approved, NABL-accredited lab.

    • Results are sent via email, WhatsApp, or the Orange Health app within 6 hours.

    Normal GGT levels fall between 15 and 73 IU/L for adults, though they may vary with lab-specific reference ranges. Higher values often indicate liver or bile duct issues or excessive alcohol consumption.

    Sample collection is done within 60 minutes, and reports are available within 6 hours.

    Your healthcare plan determines the frequency, with annual or more frequent testing based on individual needs or medical advice.

    This test specifically measures the level of Gamma Glutamyl Transferase in your blood.

    You can get a Gamma Glutamyl Transferase (GGT) test done with the added convenience of home sample collection at multiple locations in Mumbai, including major localities like Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Gamma-glutamyl Transferase (GGT) Test [Internet]. 2. ‌Gamma-glutamyl transferase (GGT) Blood Test. [Internet]. Cleveland Clinic.  Available from:  https://medlineplus.gov/lab-tests/gamma-glutamyl-transferase-ggt-test/
    2. ‌3. Whitfield JB. Gamma Glutamyl Transferase. Critical Reviews in Clinical Laboratory Sciences [Internet].  Available from:  https://pubmed.ncbi.nlm.nih.gov/11563810/
    3. ‌Gamma-glutamyl transpeptidase (GGT) blood test Information | Mount Sinai - New York [Internet].  Available from:  https://www.mountsinai.org/health-library/tests/gamma-glutamyl-transpeptidase-ggt-blood-test
    4. ‌ 5. Gamma-Glutamyl Transpeptidase - Health Encyclopedia - University of Rochester Medical Center [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=gamma_glutamyl_transpeptidase