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    What is an Estradiol (E2) Test?

    The Estradiol (E2) test measures the level of estradiol, a key hormone from the oestrogen group, in your blood. Estradiol is the primary oestrogen in women of reproductive age and is vital for sexual development. Although produced in both men and women, oestrogen levels are much higher in women. Estradiol is one of four types of oestrogen—along with oestrone (E1), oestriol (E3), and oestetrol (E4)—and is the most dominant form in women.

    Measuring estradiol levels provides valuable information about ovarian function, helping diagnose menstrual problems such as irregular or missed periods. Doctors may also use this test to assess cases of early or delayed puberty and to detect issues in the testes, ovaries, or adrenal glands. It’s also helpful in monitoring pregnancies, fertility treatments, and menopausal symptoms.

    If you live in Mumbai and are dealing with potential hormonal issues, book an Estradiol (E2) test today. Early detection can help in starting appropriate treatments without delay.

    Estradiol (E2) Test Parameters

    The Estradiol (E2) test specifically measures the concentration of Estradiol in your blood.

    In women, this hormone is primarily produced by the ovaries and adrenal glands, with additional contributions from the placenta during pregnancy. It is also synthesized in various tissues, such as the skin, brain, liver, fat, and bones. Estradiol is crucial for the development and growth of reproductive organs, including the uterus, vagina, and fallopian tubes. It also facilitates breast development, changes in external genitalia, fat distribution in the body, and the onset of menopause. In men, Estradiol is produced in small amounts by the testes, where it plays a key role in protecting sperm from premature death. Thus, the Estradiol/Oestrogen test aids in diagnosing and managing hormonal imbalances, contributing to overall health maintenance.

    Estradiol (E2) Test Preparation

    Things to Know Before Booking an Estradiol (E2) Test at Home:

    • Prerequisites

    Fasting is not required when preparing for the Estradiol test.

    • Best Time to Get Tested

    The Estradiol test can be performed at any time of day, as there are no restrictions related to timing.

    • Who Should Get an Estradiol Test

    Your doctor may recommend this test if you are experiencing symptoms related to high or low Estradiol, such as menstrual irregularities or signs of menopause. It is also used in diagnosing early puberty in children and tracking hormone levels during infertility treatments like ART.

    • Cautions Before Taking an Estradiol Test

    There are no special preparations needed for the test, but your doctor may advise you to pause certain medications, like birth control or hormone therapy, which can affect the results. Discontinue any medication only on medical advice.

    Why Take the Estradiol (E2) Test

    Estradiol plays a vital role in reproductive health and sexual development. Here are some reasons your doctor may order an Estradiol test:

    • To evaluate the function of the ovaries, adrenal glands, or placenta.

    • To investigate causes of menstrual disorders, such as missed periods or abnormal bleeding.

    • To diagnose infertility issues in women or monitor pregnancy and response to ART fertility treatments.

    • To assess symptoms of menopause, like hot flashes, or to track the effectiveness of hormone therapy in menopausal women.

    • To detect early puberty in adolescents or abnormal development of male or female body characteristics.

    • To monitor individuals with hypopituitarism or investigate conditions caused by abnormal oestrogen levels, including gynecomastia in males, ovarian tumours, or breast cancer.

    • To detect damage or disease in the reproductive organs such as the testes or ovaries.

    Note: Since human sex hormones interact closely, Estradiol testing is often paired with other hormone tests, including LH, FSH, prolactin, testosterone, progesterone, TSH, and FT4. This combination provides a fuller picture of an individual's sexual and reproductive health.

    Estradiol (E2) Test Results & Interpretation

    The table below provides the normal range for Estradiol levels in picograms per millilitre (pg/mL).

    Estradiol TestNormal Values (pg/mL)
    Males5.37 - 65.9
    Females (according to menstrual phases) Follicular Preovulatory Luteal Post Menopause26.6 - 161 187 - 382 32.7 - 201 5.37 - 38.4

    FAQs on Estradiol (E2) Test in Mumbai

    The cost of the Estradiol test in Mumbai is ₹ 1000, which includes prompt home sample collection within 60 minutes of booking, with results available in 36 hours.

    Yes, Orange Health Labs offers a home collection for Estradiol tests in Mumbai. Samples are collected from your home within 60 minutes of booking, based on available slots.

    The Estradiol test measures hormone levels to evaluate the function of the ovaries, placenta, and adrenal glands. It helps diagnose conditions like early puberty, menstrual issues, menopause, and ovarian tumours and assesses the response to hormone therapy and fertility treatments.

    No fasting is necessary for the Estradiol test.

    To book a blood test or health checkup, you can follow these steps:

    • Locate the Test: Search for the Estradiol or Oestrogen test in Mumbai and select Orange Health’s page from the listings.

    • Verify Details: Choose the E2 test, review prerequisites if any, enter your location, and complete the booking by scheduling a sample collection time.

    • Sample Collection: A trained eMedic will collect your sample at home at the scheduled time.

    • Lab Testing: Your sample will be processed in our ICMR-approved and NABL-accredited labs.

    • Receive Results: You will receive your test results by email or WhatsApp within 36 hours, with access available through our app as well.

    Normal Estradiol levels differ based on gender and the menstrual cycle stage in women. For males, the normal range is 5.37 to 65.9 pg/mL. In females, levels are 26.6-161 pg/mL during the follicular phase, 187-382 pg/mL during the preovulatory phase, 32.7-201 pg/mL in the luteal phase, and 5.37-38.4 pg/mL post-menopause.

    When you book an Estradiol test, a trained eMedic will collect your sample at home within 60 minutes. Reports are delivered within 36 hours of collection.

    The Estradiol test frequency depends on your medical needs, like checking hormone imbalances, undergoing fertility treatment, or managing menopause. Consult your doctor for personalized advice on testing intervals.

    The test for Estradiol includes only one parameter, which is the Estradiol level in the blood.

    Orange Health offers convenient home Estradiol testing across various localities in Mumbai, eliminating the need for a lab visit. We serve at various locations including but not limited to Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Estradiol blood test [Internet]. UCSF Health.  Available from:  https://www.ucsfhealth.org/medical-tests/estradiol-blood-test
    2. Oestrogen blood test [Internet]. Health Direct.  Available from:  https://www.healthdirect.gov.au/oestrogen-blood-test
    3. Hariri L, Rehman A. Estradiol. [Updated 2023 Jun 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK549797/
    4. Blood Test: Estradiol [Internet]. The Nemours Foundation.  Available from:  https://kidshealth.org/en/parents/blood-test-estradiol.html