The Dengue NS1 Antigen ELISA test identifies the non-structural protein 1 (NS1) of the dengue virus in blood samples. This antigen, representing any foreign material like viruses entering the body, can be detected during the first 7 days of dengue fever, known as the acute phase. Early detection through the NS1 test allows for timely diagnosis and medical intervention.
Dengue fever, a mosquito-borne illness, is triggered by one of the four serotypes of the dengue virus from the genus Flavivirus. Upon being bitten by an infected mosquito, the virus enters the bloodstream and starts replicating. This viral activity and the body's immune response cause dengue fever symptoms. The Dengue NS1 test can detect the virus in blood within the first 7 days of symptom onset. Research indicates that NS1 antigen levels in the blood correlate with disease severity, with higher levels found in severe cases. Therefore, the Dengue Antigen test offers valuable diagnostic insight into dengue infections.
If you live in Mumbai and exhibit symptoms of dengue fever, scheduling a Dengue Antigen test can be crucial. Book your Dengue Antigen test in Mumbai today to determine your dengue status.
Dengue NS1 Antigen ELISA Test Parameters
Dengue is transmitted through the bite of Aedes mosquitoes. When a mosquito bites a person with dengue fever and then bites a healthy individual, it spreads the infection. The dengue virus can damage blood components responsible for clotting and maintaining blood vessel structure. This damage, along with certain immune system chemicals, can cause blood to leak from vessels. This may lead to internal bleeding. Therefore, prompt testing is crucial if symptoms arise.
The Dengue NS1 Antigen test targets a single key parameter: the detection of the dengue NS1 protein, which is released into the blood during infection. This test is performed on a blood sample using special antibodies designed to detect the NS1 antigen. The immune system produces antibodies, which are proteins, in reaction to antigens such as NS1. The identification of NS1 in the blood confirms an acute dengue virus infection, but its absence does not rule out infection. Additional tests may be necessary to confirm the diagnosis.
Dengue NS1 Antigen ELISA Test Preparation
Here are key factors to consider before a Dengue Fever NS1 Antigen test:
Prerequisites
No fasting is required for the Dengue NS1 test.
Best Time to Get Tested
The Dengue Antigen test can be performed at any time of day.
Who Should Consider a Dengue NS1 ELISA Test
This test is recommended if you live in or have travelled to an area with a high prevalence of dengue and exhibit recent symptoms such as high fever, rash, muscle and joint pain, pain behind the eyes, nausea, and vomiting.
Cautions Before Taking Dengue NS1 ELISA Test
No special precautions are necessary before taking the Dengue NS1 test.
Why Take a Dengue NS1 Antigen ELISA Test?
If you reside in or have travelled to a dengue-prone area and have recently exhibited symptoms of dengue fever, you should take a Dengue NS1 test. Dengue fever symptoms generally appear within 4 to 10 days after a mosquito bite and last for 3 to 7 days. Common symptoms include a sudden high fever of up to 104°F or higher, accompanied by any of the following symptoms:
Rash
Nausea and vomiting
Severe pain behind the eyes
Headache
Muscle, bone, or joint pain
If left untreated, some individuals may develop a severe form of dengue called dengue haemorrhagic fever, which can cause bleeding gums, nosebleeds, abdominal pain, frequent vomiting, vomiting blood, blood in stools, and extreme fatigue. The risk of severe dengue highlights the importance of early detection and treatment.
The NS1 antigen is identifiable in the blood during the acute phase of infection, so the NS1 test is performed within the first 7 days of symptom onset. After this period, the test may lose sensitivity in diagnosing dengue.
The Dengue Antigen test therefore aids doctors in early dengue detection, confirming infection, and ruling out other illnesses with similar symptoms.
Dengue NS1 Antigen ELISA Test Results & Interpretation
The interpretation of Dengue NS1 ELISA test findings is explained in the table below:
NS1 Results
Index Values
Interpretation
Negative
≤0.8
Retest if NS1 antigen is not found. Further assessment is needed if symptoms persist.
Equivocal
0.8 to 1.1
Should undergo testing using an alternative method.
Positive
≥1.1
Indicates a dengue virus infection.
It is important to note that interference may occur in some cases where the blood sample contains antibodies against test components. For example, during dengue virus testing, cross-reactivity with other Flaviviruses or non-infectious conditions might lead to false-positive results or misinterpretation. Therefore, considering the patient's clinical history is crucial for an accurate diagnosis. Combining NS1 detection with the IgM Antibody test can improve the accuracy of diagnosing dengue infection. The dengue NS1 ELISA is the preferred test within the first 7 days of symptom onset. After 7-10 days, IgG and IgM antibody tests are recommended.
FAQs on Dengue NS1 Antigen ELISA Test in Mumbai
The Orange Health Experience
Choose precision
On time, every time!
98% on time collections with a 60 minutes promise
99% reports are delivered on time within 6 hours
Not a pilot, just as precise
Meet our expert eMedics!
Hygienic, well groomed, and professional eMedics
With over 100 hours of training
No more painful pricks
Experience painless testing!
Our eMedics are trained for a single, painless prick.
Don’t believe us? We asked our customers and here is what they said - 98% of customers experienced no pain during sample collection!
The most organised sample collection box and experience
Trust our fully automated and certified labs
For accurate testing
NABL and ICMR certified labs
eQAS partnership with AIIMS and CMC Vellore
We have our own fully automated labs in all 4 cities we are available in
Customers love us
The highest rated lab!
Google rating: 4.9/5 (16000+ reviews)
1 million+ customers tested
What people say about us
Payment & Refund Policy
We do not accept cash payments
All modes of online payment are accepted
Refunds will be credited back to the source of payment within 3 hours of order cancellation.