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    What is Gamma Glutamyl Transferase (GGT) Test?

    The gamma-glutamyl transferase (GGT) test is a blood test that measures the levels of GGT, an enzyme predominantly found in the liver. Enzymes are specialized proteins responsible for facilitating crucial chemical processes in the body. Although GGT exists in various tissues, its highest concentration is in the liver, where it helps protect cells from damage.

    This test is widely used to evaluate liver health and detect issues such as liver damage or blockages in the bile ducts. Bile ducts are essential for transporting bile—a digestive fluid produced by the liver—into and out of the organ. High levels of GGT in the blood often suggest liver disease, bile duct obstruction, or damage due to factors like alcohol use, medications, or other conditions impacting the liver, pancreas, or heart. The GGT test is commonly performed alongside other liver function tests, including the alkaline phosphatase (ALP) test.

    For those interested in checking their liver health, Gamma Glutamyl Transferase (GGT) testing is available at home. Orange Health Labs provides convenient home testing services for the Gamma Glutamyl Transferase (GGT) test in Hyderabad.

    Gamma Glutamyl Transferase (GGT) Test Parameters

    The GGT test evaluates a single parameter: the level of GGT in the blood. This enzyme is a recognized marker for liver dysfunction and can also indicate alcohol use disorder. Apart from its diagnostic significance, GGT has an important physiological role in defending the body against damage from harmful substances called free radicals. It achieves this by breaking down glutathione, a vital compound, into smaller components that cells can use.

    Elevated GGT levels typically signify damaged bile ducts (the tubes in the liver that transport bile) or liver-related abnormalities. Such increases are often associated with liver diseases, excessive alcohol consumption, or certain medications. These conditions can elevate free radical levels in the body and deplete glutathione, which is essential for combating harmful substances. Consequently, GGT provides valuable insight into broader health risks.

    Gamma Glutamyl Transferase (GGT) Test Preparation

    Here’s how you can prepare for a GGT test conducted at home:

    • Prerequisites No special preparations, such as fasting, are needed before undergoing the GGT test.

    • Best Time to Get Tested You can schedule the GGT test at any time of the day based on your convenience.

    • Who Should Get a GGT Test This test is advised for individuals showing signs of liver disease, including jaundice (yellowing of the skin and eyes), unexplained fatigue, or abdominal discomfort. It is also recommended for those with a history of heavy alcohol consumption or who are taking medications that could impact liver health. Furthermore, individuals managing ongoing liver disease or conditions such as diabetes or heart disease that can affect liver function should consider this test for monitoring purposes.

    • Cautions Before Taking a GGT Test Since alcohol and certain medications can influence GGT levels, it is advisable to avoid alcohol for at least 24 hours before the test. Inform your doctor about any medications you are currently taking, as drugs like acetaminophen, phenytoin, and phenobarbital can raise GGT levels, while birth control pills and clofibrate may lower them. Recent illnesses or surgeries should also be discussed with your doctor, as these factors may affect test outcomes.

    Why Take the Gamma Glutamyl Transferase (GGT) Test?

    The GGT test is a crucial tool for assessing liver health and detecting various liver-related conditions. It plays a vital role in evaluating liver and bile duct function and is particularly helpful in the following scenarios:

    • Diagnosing liver diseases and detecting possible liver damage.

    • Identifying blockages in the bile ducts.

    • Screening or monitoring for alcohol use disorder (AUD), as alcohol consumption can elevate GGT levels.

    • Differentiating whether high GGT levels are linked to liver conditions or bone disorders.

    • Investigating symptoms such as fatigue, jaundice (yellowing of the skin and eyes), abdominal discomfort, nausea, and severe itching.

    • Following up on abnormal findings from other liver function tests, like ALP, to gain better insights into liver or bile duct health.

    FAQs on Gamma Glutamyl Transferase (GGT) Test in Hyderabad

    The price for a Gamma Glutamyl Transferase (GGT) test in Hyderabad is ₹230. This includes home sample collection, which will be completed within 60 minutes of booking.

    Yes, Orange Health Labs provides home sample collection for GGT tests. After scheduling the test, an eMedic will visit your home within 60 minutes to collect the sample.

    The GGT test evaluates liver health, helps diagnose liver disease, detects bile duct blockages, and monitors alcohol use disorder. It also distinguishes liver damage from bone-related issues.

    Fasting is not typically required for the GGT test.

    To book the test:

    • Search for the test online and select the Orange Health website.

    • Verify details such as prerequisites and your location, and choose a convenient sample collection time.

    • Sample collection is performed at your home by a trained eMedic.

    • Lab processing occurs at an ICMR-certified and NABL-accredited facility.

    • Receive results via email, WhatsApp, or the Orange Health app within 6 hours.

    Normal levels generally range from 15-73 IU/L for adults, varying by age, gender, and laboratory standards. Elevated levels suggest possible liver damage, bile duct obstructions, or excessive alcohol use.

    Your sample will be collected within 60 minutes, and results will be available within 6 hours of collection.

    The frequency depends on individual health conditions. Annual testing may be recommended for those at risk, with more frequent testing as advised for ongoing conditions.

    The GGT test measures the enzyme concentration of Gamma Glutamyl Transferase in the blood.

    You can get a Gamma Glutamyl Transferase (GGT) test done with the added convenience of home sample collection at multiple locations in Hyderabad, including major localities like Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. Gamma-glutamyl Transferase (GGT) Test [Internet]. 2. ‌Gamma-glutamyl transferase (GGT) Blood Test. [Internet]. Cleveland Clinic.  Available from:  https://medlineplus.gov/lab-tests/gamma-glutamyl-transferase-ggt-test/
    2. ‌3. Whitfield JB. Gamma Glutamyl Transferase. Critical Reviews in Clinical Laboratory Sciences [Internet].  Available from:  https://pubmed.ncbi.nlm.nih.gov/11563810/
    3. ‌Gamma-glutamyl transpeptidase (GGT) blood test Information | Mount Sinai - New York [Internet].  Available from:  https://www.mountsinai.org/health-library/tests/gamma-glutamyl-transpeptidase-ggt-blood-test
    4. ‌ 5. Gamma-Glutamyl Transpeptidase - Health Encyclopedia - University of Rochester Medical Center [Internet].  Available from:  https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=gamma_glutamyl_transpeptidase