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    What is an Estradiol (E2) Test?

    The Estradiol (E2) test measures the level of estradiol, an important hormone within the oestrogen group, in your blood. Estradiol is the primary form of oestrogen in women during their reproductive years and plays a significant role in sexual development. Although both men and women produce oestrogen, it is much more prevalent in women. Estradiol, which is one of four types of oestrogen—alongside oestrone (E1), oestriol (E3), and oestetrol (E4)—is the most potent and predominant form.

    This test provides insights into ovarian function, aiding in the diagnosis of menstrual disorders such as irregular or absent periods. It can also be used to evaluate cases of early or delayed puberty and to detect issues in the testes, ovaries, or adrenal glands. The test is also valuable in monitoring pregnancies, fertility treatments, and symptoms related to menopause.

    If you're in Hyderabad and facing concerns with your estradiol levels, schedule an Estradiol (E2) test today to help identify any issues early and ensure prompt treatment.

    Estradiol (E2) Test Parameters

    The Estradiol (E2) test measures a single parameter: the level of Estradiol in the blood.

    In women, Estradiol is mainly produced by the ovaries and adrenal glands, and during pregnancy, it is also released from the placenta. Additionally, other tissues, such as the skin, fat, bone, liver, and brain, contribute to Estradiol production. This hormone is vital for various reproductive functions, including the growth of the uterus, fallopian tubes, and vagina, as well as breast development, body fat distribution, changes in external genitalia, and regulating menopause. In men, the testes produce a small amount of Estradiol, which plays a role in preventing premature sperm death. Therefore, an Estradiol/Oestrogen test is essential in evaluating hormonal balance and overall health.

    Estradiol (E2) Test Preparation

    Consider the following points before scheduling an Estradiol (E2) test at home:

    • Prerequisites

    Fasting is not a requirement for the Estradiol test.

    • Best Time to Get Tested

    The Estradiol test can be performed at any time during the day.

    • Who Should Get an Estradiol Test

    An Estradiol test may be indicated if your doctor is investigating potential issues with Estradiol levels, which could manifest as menstrual irregularities or menopause-related symptoms. The test is also valuable in diagnosing early puberty in adolescents and tracking hormone levels during ART for infertility.

    • Cautions Before Taking an Estradiol Test

    No specific preparations are necessary for the Estradiol test. However, your doctor may advise you to discontinue certain medications, such as hormone therapy or birth control pills, which can affect the results. Always consult your healthcare provider before making any changes to your medication regimen.

    Why Take the Estradiol (E2) Test

    The Estradiol test is crucial for evaluating sexual development and reproductive health. Reasons for ordering this test include:

    • Diagnosing the cause of menstrual issues like missed periods or abnormal bleeding.

    • Evaluating abnormal male or female physical development.

    • Assessing ovarian, placental, or adrenal gland function.

    • Determining infertility causes or monitoring pregnancy and fertility treatments like ART.

    • Detecting early puberty in adolescents or damage and disease in reproductive organs like the ovaries and testes.

    • Evaluating symptoms of menopause, such as hot flashes, and tracking the effectiveness of hormone therapy in menopausal women.

    • Monitoring individuals with hypopituitarism or identifying conditions related to abnormal oestrogen levels, such as gynecomastia in males, ovarian tumours, or breast cancer.

    Note: Estradiol works closely with other sex hormones, so it is often tested alongside LH, FSH, prolactin, testosterone, progesterone, TSH, and FT4 to gain a complete understanding of an individual's reproductive and sexual health.

    Estradiol (E2) Test Results & Interpretation

    The table below provides the normal range for Estradiol levels in picograms per millilitre (pg/mL).

    Estradiol TestNormal Values (pg/mL)
    Males5.37 - 65.9
    Females (according to menstrual phases) Follicular Preovulatory Luteal Post Menopause26.6 - 161 187 - 382 32.7 - 201 5.37 - 38.4

    FAQs on Estradiol (E2) Test in Hyderabad

    The price for an Estradiol test in Hyderabad is ₹ 1000. This cost includes a rapid home sample collection within 60 minutes of test confirmation, and results will be ready in 36 hours.

    Yes, Orange Health Labs provides the convenience of home sample collection for the Estradiol test in Hyderabad. The sample can be collected within 60 minutes of booking, subject to availability.

    An Estradiol test checks hormone levels to assess the health of the ovaries, placenta, and adrenal glands. It’s used to diagnose early puberty, menstrual disorders, menopause, and ovarian tumours, and to track the effectiveness of hormone therapy and fertility treatments.

    Fasting is not required for an Estradiol test.

    Here’s how you can book a blood test or health checkup:

    • Find the Test: Search for the Estradiol or Oestrogen test in Hyderabad and select Orange Health’s listing from the results.

    • Verify and Book: Click on the E2 test, review prerequisites, add your location, and pick a time for the sample collection that works for you.

    • Collection at Home: A trained eMedic will visit your home at the selected time to collect the sample.

    • Lab Processing: The sample will be analyzed at our labs, which are ICMR-approved and NABL-accredited.

    • Receive Your Results: The results of your Oestrogen test will be sent via email or WhatsApp within 36 hours and can also be accessed through our app.

    Estradiol levels can vary depending on gender and menstrual cycle phase. Typical levels for men are between 5.37 and 65.9 pg/mL. For women, values change with the cycle: 26.6-161 pg/mL during the follicular phase, 187-382 pg/mL in the preovulatory phase, 32.7-201 pg/mL in the luteal phase, and 5.37-38.4 pg/mL after menopause.

    Once the Estradiol test is booked, Orange Health Labs sends an eMedic to collect the sample within 60 minutes. The collection is quick, and results are sent online within 36 hours.

    Your doctor will determine how often you should have an Estradiol test based on your health needs, such as hormonal monitoring, fertility treatments, or assessing menopausal symptoms. Follow your doctor’s recommendations.

    An Estradiol test solely measures the concentration of Estradiol in the bloodstream.

    In Hyderabad, Orange Health delivers Estradiol testing at your home, covering multiple localities without requiring a lab visit We serve locations like Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. Estradiol blood test [Internet]. UCSF Health.  Available from:  https://www.ucsfhealth.org/medical-tests/estradiol-blood-test
    2. Oestrogen blood test [Internet]. Health Direct.  Available from:  https://www.healthdirect.gov.au/oestrogen-blood-test
    3. Hariri L, Rehman A. Estradiol. [Updated 2023 Jun 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK549797/
    4. Blood Test: Estradiol [Internet]. The Nemours Foundation.  Available from:  https://kidshealth.org/en/parents/blood-test-estradiol.html