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    What is Apolipoprotein A1 (Apo-A1) Test?

    The Apolipoprotein A1 (Apo A1) test measures the concentration of a protein that plays a key role in cholesterol transport. Apolipoproteins help form lipoproteins, which carry cholesterol in the bloodstream. Apo A1 is a crucial part of high-density lipoprotein (HDL), often referred to as "good cholesterol." HDL helps clear excess cholesterol, preventing buildup in the arteries. Lower levels of Apo A1 may indicate a reduced number of "good cholesterol" particles, increasing the risk of heart disease and circulation problems. Doctors may suggest this test for people with high cholesterol, a genetic predisposition to heart disease, or hyperlipidaemia. It is also used to track the effectiveness of cholesterol-lowering treatments and lifestyle modifications. Factors such as kidney disease, diabetes, smoking, and certain medications can contribute to low Apo A1 levels, while higher levels are generally linked to positive influences like exercise, weight loss, or pregnancy. This test is not routinely performed but can provide additional cardiovascular insights and complement standard cholesterol tests when necessary.

    Apolipoprotein A1 (Apo-A1) Test Parameters

    The Apo A1 test measures the concentration of Apolipoprotein A1 in the blood, a protein that constitutes about 65% of HDL. Apo A1 is essential for HDL formation and facilitates the action of lecithin cholesterol acyltransferase (LCAT), an enzyme that converts cholesterol into a form that can be expelled from the body. HDL plays a key role in removing excess cholesterol by transporting it from body tissues to the liver, where it is processed and eliminated. When Apo A1 levels are low, cholesterol clearance may be compromised, increasing the likelihood of cardiovascular disease and circulatory issues. Lower Apo A1 levels are frequently observed in individuals with atherosclerosis. While genetic factors can impact Apo A1 levels, not all genetic changes contribute to heart disease. Doctors commonly measure both Apo A1 and Apolipoprotein B (Apo B) to assess cardiovascular health. The ratio of these two proteins provides a more detailed picture of heart disease risk than standard cholesterol testing.

    Apolipoprotein A1 (Apo-A1) Test Preparation

    Here’s what you need to know before getting the Apolipoprotein A test at home:

    Prerequisites

    No fasting or special preparations are needed for the Apo A1 test.

    Best Time to Get Tested

    This test can be conducted at any time of the day.

    Who Should Get an Apolipoprotein A1 Test?

    It is beneficial for individuals with a history of high cholesterol, heart disease in the family, or those monitoring cholesterol levels due to lifestyle or medication use.

    Cautions Before Taking Apolipoprotein A1 Test

    No specific precautions are required before testing.

    Why Take the Apolipoprotein A1 (Apo-A1) Test?

    The Apolipoprotein A1 testing may be suggested for:

    • Individuals managing high cholesterol through medication or lifestyle changes

    • Evaluating the balance between Apo A1 and Apo B for a better cholesterol profile

    • Identifying genetic factors that lead to low HDL cholesterol levels

    • Individuals with a strong family history of premature heart disease

    • Individuals diagnosed with hyperlipidaemia or at risk of cholesterol-related issues

    This test is more precise than routine HDL cholesterol tests and helps in a comprehensive assessment of heart health.

    FAQs on Apolipoprotein A1 (Apo-A1) Test in Hyderabad

    In Hyderabad, the Apo A1 test costs ₹650. The fee includes a home sample collection service, which is completed within 60 minutes of booking confirmation. Test reports will be available within 6 hours after collection.

    Yes, home sample collection is offered by Orange Health Labs for the Apo A1 test in Hyderabad. A trained eMedic will collect your sample within 60 minutes of booking, depending on availability.

    The Apo A1 test determines the levels of apolipoprotein A1, a component of HDL cholesterol, which helps assess cardiovascular health. It is often recommended for individuals with elevated cholesterol or a family history of heart disease.

    No fasting is needed before taking this test. However, it is advisable to follow your doctor's instructions if any specific preparation is necessary.

    Booking an Apolipoprotein A1 test with Orange Health Labs in Hyderabad is quick and easy:

    • Find your test : Head to the Orange Health website and look up the Apolipoprotein A1 test for Hyderabad.

    • Confirm your booking : Select the test, go through the instructions, enter your location, and choose a suitable time.

    • Blood sample collection : A trained eMedic will visit your home and collect the sample after your booking is confirmed.

    • Laboratory testing : The sample will be analyzed at a NABL-accredited, ICMR-approved laboratory.

    • Receive results : Your test results will be shared via email or WhatsApp within 6 hours, with access available through the Orange Health app.

    For most individuals, Apolipoprotein A1 levels should be within 105-175 mg/dL.

    Your sample is collected by an eMedic within 60 minutes of booking. Results are available within 6 hours post-collection.

    The necessity of conducting this test repeatedly varies per person. Consult your doctor to determine the right testing frequency based on your health condition.

    This test assesses only one factor—the level of Apolipoprotein A1, an important protein in HDL cholesterol.

    Orange Health offers at-home sample collection for this test in different Hyderabad locations, including Banjara Hills, Jubilee Hills, Gachibowli, Madhapur, Hitech City, Kondapur, Begumpet, Somajiguda, Ameerpet, Panjagutta, Kukatpally, Miyapur, Manikonda, Secunderabad, Tarnaka, Abids, Koti, Mehdipatnam, Dilsukhnagar, Uppal, LB Nagar, Nallagandla, Nizampet, Attapur, Malkajgiri.

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    References

    1. Apolipoprotein A-1 | Pathology Tests Explained [Internet].  Available from:  https://www.pathologytestsexplained.org.au/ptests-pro.php?q=Apolipoprotein+A-1
    2. Apolipoprotein A1 – Supra-Regional Assay Service [Internet].  Available from:  https://www.sas-centre.org/assays/cardiovascular-biomarkers/apolipoprotein-a1