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    What is a Dengue NS1 Antigen ELISA Test?

    The Dengue NS1 Antigen ELISA test detects the non-structural protein 1 (NS1) of the dengue virus in a blood sample, targeting specific antigens (foreign substances) that enter the body. Detection is possible within the first 7 days of dengue fever, known as the acute phase, aiding early diagnosis and prompt medical care.

    Mosquito bites transmit dengue fever, which is caused by one of four serotypes of the Flavivirus genus. Once an infected mosquito bites a person, the virus enters the bloodstream and begins to multiply leading to dengue fever symptoms (caused by both the virus and the immune system's reaction). The Dengue NS1 test can detect the virus in blood within the initial 7 days of symptoms. Research shows a correlation between NS1 antigen levels in the blood and disease severity, with higher levels in severe cases. Hence, the Dengue Antigen test offers valuable diagnostic information for managing dengue infections.

    For residents of Gurgaon with dengue symptoms, a Dengue Antigen test can be very useful. Schedule your Dengue Antigen test in Gurgaon today to determine your dengue status if you believe you have been exposed to the virus.

    Dengue NS1 Antigen ELISA Test Parameters

    Dengue is transmitted through the bite of Aedes mosquitoes. When an infected mosquito bites someone with dengue and then bites a healthy individual, it spreads the infection. The dengue virus can harm blood components which create clots and keep blood vessels intact. This damage, along with immune system chemicals, can cause blood to leak from vessels, causing internal bleeding. Therefore, if symptoms appear, timely testing is required.

    The Dengue NS1 Antigen test has a single parameter: detection of the dengue NS1 protein, which is released into the blood during infection. This test is conducted on a blood sample using special antibodies to detect the NS1 antigen. Antibodies are proteins produced by the immune system in response to antigens like NS1. The detection of NS1 in the blood determines an acute dengue virus infection; nevertheless, the lack of NS1 does not rule out infection. Additional tests may be needed to confirm the diagnosis.

    Dengue NS1 Antigen ELISA Test Preparation

    Basic guidelines for the Dengue Fever NS1 Antigen test include:

    Prerequisites

    Fasting is not a prerequisite for the Dengue NS1 test.

    Best Time to Get Tested

    The Dengue Antigen test can be done at any time.

    Eligibility for Dengue NS1 ELISA Test

    You should get this test if you have been in a region with dengue outbreaks and have symptoms such as high fever, rash, pain behind the eyes, muscle and joint pain, nausea, and vomiting.

    Cautions Before Taking Dengue NS1 ELISA Test

    No special precautions are necessary before taking the Dengue NS1 test.

    Why Take a Dengue NS1 Antigen ELISA Test?

    A Dengue NS1 test is advised if you live in or have travelled to an area where dengue fever is common and have recently shown symptoms of the disease. Dengue fever symptoms usually manifest within 4 to 10 days after a mosquito bite and last for 3 to 7 days. The symptoms often include a rapid onset of fever reaching up to 104°F or higher, along with any of the following symptoms:

    • Rash

    • Headache

    • Severe pain behind the eyes

    • Muscle, bone or joint pain

    • Nausea

    • Vomiting

    If not properly managed, some individuals can develop dengue haemorrhagic fever, a serious condition causing nosebleeds, bleeding gums, abdominal pain, frequent vomiting, vomiting blood, blood in stools, and extreme fatigue. This risk stresses the importance of early detection and treatment.

    The NS1 antigen is detectable in the blood during the acute phase of infection, so the NS1 test is conducted within the first 7 days of symptoms. After the first week, the test may lose some of its sensitivity.

    Therefore, the Dengue Antigen test supports doctors in early dengue detection, confirming the infection, and distinguishing it from other similar illnesses.

    Dengue NS1 Antigen ELISA Test Results & Interpretation

    The following table shows how to interpret the findings of a Dengue NS1 ELISA test:

    NS1 ResultsIndex ValuesInterpretation
    Negative≤0.8Retest if NS1 antigen is not found. Further assessment is needed if symptoms persist.
    Equivocal0.8 to 1.1Should undergo testing using an alternative method.
    Positive≥1.1Indicates a dengue virus infection.

    It is essential to note that interference may happen when the blood sample contains antibodies against test components. For instance, during dengue virus testing, cross-reactivity with other Flaviviruses or non-infectious conditions can result in false positives or misinterpretations. Therefore, considering the patient's clinical history is crucial for accurate diagnosis. Using both NS1 detection and the IgM Antibody test can enhance diagnostic accuracy for dengue infection. The dengue NS1 ELISA is the preferred test within the initial 7 days of symptom onset, with IgG and IgM antibody tests recommended after 7-10 days.

    FAQs on Dengue NS1 Antigen ELISA Test in Delhi

    The Dengue NS1 Antigen ELISA test price is ₹600. This cost covers the quickest possible home sample collection, which is completed within 60 minutes of scheduling, and the reports are available in 12 hours.

    The Dengue NS1 Antigen test is used to confirm dengue infection during the initial 7-day period following symptom onset.

    No, fasting is not required for this test.

    Yes, Orange Health Labs provides home sample collection service for the Dengue NS1 ELISA test. An eMedic will arrive at your location for sample collection within 60 minutes of booking the test, subject to slot availability. You also have the option of booking the test at your preferred date and time.

    To book any blood test or health checkup on our platform, follow these steps:

    • Search for the Test : Find the Dengue fever NS1 Antigen test in Gurgaon or at home and select Orange Health’s listing.

    • Review and Book : Choose the test, review the prerequisites, input your address, and confirm the booking by selecting a convenient time slot for sample collection.

    • Sample Collection : Our proficient eMedic will arrive during your chosen time slot to collect the sample at your residence.

    • Lab Processing : The collected sample will be sent to our NABL accredited and ICMR approved labs for examination.

    • Receive Results : Expect your reports via email, WhatsApp, or through our app within 12 hours of sample collection.

    The Dengue NS1 ELISA test results are interpreted in the following manner:

    • Negative: Index values ≤0.8. Absence of NS1 antigen necessitates retesting.

    • Equivocal: Index values from 0.8 to 1.1. Additional testing with an alternative method is recommended.

    • Positive: Index values ≥1.1, confirming a dengue virus infection.

    The Orange Health Labs eMedic will arrive at your location within 60 minutes of booking your test. Sample collection is generally done in under 5 minutes, and you can anticipate receiving your results online in 12 hours.

    The frequency of testing depends on your doctor's advice, which is generally based on your symptoms, test results, and any underlying conditions. Typically, this test is recommended just once during the early stages of a dengue infection.

    The only parameter of the Dengue NS1 Antigen test is the detection of the NS1 protein, which is found in the blood during the infection.

    The Dengue NS1, IgM, and IgG tests are designed to detect distinct components of the virus and the body's immune response to dengue infection:

    • NS1 test: Detects the NS1 protein of the virus, which is present in the blood during the early phase of infection, detectable from day 1 to day 7 of symptom onset.

    • IgM test: Detects IgM antibodies, which become detectable from days 3 to 5 of infection and remain for 2 to 3 months.

    • IgG test: Detects IgG antibodies, which generally appear by day 14 of infection and persist for life.

    The combined results from these antigen and antibody tests are used to confirm a current dengue virus infection.

    Yes, in some individuals, the NS1 protein can remain detectable in the blood for a few additional days after the acute phase of infection.

    While a positive NS1 test confirms the presence of dengue infection, it does not identify the virus's serotype. To identify the serotype, the sample needs to be tested with nucleic acid amplification tests (NAAT) such as real-time reverse transcriptase-polymerase chain reaction (RT-PCR), which detect and determine the genetic material of the dengue virus.

    If exposed to the virus but with a negative NS1 test result, it does not necessarily exclude a dengue infection. Your doctor may suggest further tests, including NAAT (RT-PCR) or an IgM antibody test, to validate the diagnosis.

    With the comfort of your home, Orange Health offers the quickest Dengue Fever NS1 Antigen test services in Gurgaon that do not require you to go to a physical lab. Localities include but are not limited to DLF Phase 1, DLF Phase 2, DLF Phase 3, DLF Phase 4, DLF Phase 5, Sector 14, Sector 15, Sector 21, Sector 22, Sector 23, Sector 24, Sector 29, Sector 31, Sector 40, Sector 42, Sector 43, Sector 45, Sector 46, Sector 50, Sector 51, Sector 52, Sector 53, Sector 54, Sector 55, Sector 56.

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