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    What is an Estradiol (E2) Test?

    The Estradiol (E2) blood test measures the amount of estradiol, a key hormone in the oestrogen family, in your blood. Estradiol is the main form of oestrogen in women during their reproductive years and plays a crucial role in sexual development. While oestrogen is present in both men and women, its levels are significantly higher in women. Estradiol is one of four types of oestrogen—alongside oestrone (E1), oestriol (E3), and oestetrol (E4)—and is the most potent.

    Monitoring estradiol levels helps evaluate ovarian function and can be crucial in diagnosing menstrual irregularities like missed or abnormal periods. This test is also useful in assessing early or delayed puberty and can help detect conditions affecting the testes, ovaries, or adrenal glands. Additionally, it plays a role in monitoring pregnancy, fertility treatments, and symptoms of menopause.

    If you are in Delhi and suspect abnormal Estradiol levels, consider scheduling an Estradiol (E2) test. Early detection of hormonal imbalances can aid in timely intervention and treatment.

    Estradiol (E2) Test Parameters

    The Estradiol (E2) test is designed to measure the level of Estradiol in the blood, focusing on a single parameter.

    In women, Estradiol is mainly produced by the ovaries and adrenal glands, with additional amounts from the placenta during pregnancy. It is also produced in other tissues, including the skin, fat, brain, bone, and liver. Estradiol is crucial for several functions, such as the growth of the uterus, fallopian tubes, and vagina, body fat distribution, breast development, changes in the external genitalia, and initiating menopause. In men, Estradiol is produced in small quantities by the testes and helps prevent the premature death of sperm. Therefore, an Estradiol/Oestrogen test is valuable in assessing hormonal balance and managing related health conditions.

    Estradiol (E2) Test Preparation

    Considerations Before Scheduling an Estradiol (E2) Test at Home:

    • Prerequisites

    No fasting is necessary for the Estradiol test.

    • Best Time to Get Tested

    You can schedule the Estradiol test at any time of the day, as the timing does not affect the results.

    • Who Should Get an Estradiol Test

    This test is recommended if your doctor suspects abnormalities in Estradiol levels, which may cause menstrual issues or menopausal symptoms. It is also useful for diagnosing early or delayed puberty in adolescents and for monitoring hormone levels during fertility treatments like assisted reproductive technology (ART).

    • Cautions Before Taking an Estradiol Test

    There are no special preparations required for this test. However, your doctor may suggest temporarily stopping certain medications, such as birth control pills or hormone therapy, that could affect the test outcomes. Make sure to consult your treating doctor before discontinuing any prescribed medication.

    Why Take the Estradiol (E2) Test

    The Estradiol test is useful for assessing reproductive health and development due to Estradiol’s key role in sexual development. This test may be ordered to:

    • Investigate the cause of menstrual irregularities, such as missed periods, abnormal bleeding, or cessation of menstruation.

    • Determine the cause of infertility in women.

    • Monitor pregnancy or evaluate a woman's response to fertility treatments like ART.

    • Assess the function of the ovaries, placenta, or adrenal glands.

    • Evaluate symptoms of menopause, including hot flashes.

    • Diagnose early puberty in adolescents.

    • Detect conditions such as hypopituitarism, or damage and disease in the testes, ovaries, or adrenal glands.

    • Evaluate abnormal development of male or female physical characteristics.

    • Monitor the effectiveness of hormone therapy in menopausal women.

    • Identify causes of abnormal oestrogen levels, such as gynecomastia in males, ovarian tumours, or breast cancer.

    Note: Since sex hormones often interact closely, an Estradiol test is typically done alongside tests for other hormones like LH, FSH, prolactin, testosterone, progesterone, TSH, and FT4. This combination of tests provides a comprehensive overview of an individual's reproductive and sexual health.

    Estradiol (E2) Test Results & Interpretation

    The table below provides the normal range for Estradiol levels in picograms per millilitre (pg/mL).

    Estradiol TestNormal Values (pg/mL)
    Males5.37 - 65.9
    Females (according to menstrual phases) Follicular Preovulatory Luteal Post Menopause26.6 - 161 187 - 382 32.7 - 201 5.37 - 38.4

    FAQs on Estradiol (E2) Test in Delhi

    The cost of an Estradiol test is ₹ 1000. This includes the quickest home sample collection within 60 minutes after test confirmation, with results delivered in 80 hours.

    Yes, Orange Health Labs offers home sample collection for the Estradiol test in Delhi. Your sample will be collected from your home within 60 minutes of booking, depending on slot availability.

    The Estradiol test measures the levels of estradiol hormones to evaluate the function of the ovaries, placenta, and adrenal glands. It aids in diagnosing conditions such as early puberty, menstrual irregularities, menopause, and ovarian tumours, and helps monitor hormone therapy and fertility treatments.

    No fasting is needed before an Estradiol test.

    To book an Estradiol test or health checkup with us, follow these steps:

    • Search for the Test: Look for the Estradiol or Oestrogen test in Delhi and click on Orange Health’s page from the options listed.

    • Confirm Details: Choose the E2 test, check any requirements, input your location, and schedule a sample collection at a time that suits you.

    • Sample Collection: A skilled eMedic will arrive at your home at the chosen time to collect the sample.

    • Lab Analysis: The collected sample will be processed at our ICMR-approved and NABL-accredited laboratories.

    • Get Results: Your test results will be emailed or sent via WhatsApp within 80 hours and can also be viewed through our app.

    Normal Estradiol levels differ by gender and menstrual phase in females. For men, levels range from 5.37 to 65.9 pg/mL.

    In women, the normal values vary from 26.6 to 161 pg/mL in the follicular phase, 187 to 382 pg/mL in the preovulatory phase, 32.7 to 201 pg/mL in the luteal phase, and 5.37 to 38.4 pg/mL post-menopause.

    After booking the Estradiol test, an eMedic will arrive to collect your sample within 60 minutes. Collection typically takes just a few minutes, and the results are available online within 80 hours.

    The frequency of an Estradiol test depends on your specific health requirements, such as monitoring hormone levels, fertility treatments, or managing menopausal symptoms. Your doctor will advise you on how often to take the test.

    The Estradiol test measures just one parameter: the level of Estradiol in your blood.

    Orange Health provides fast Estradiol testing services throughout Delhi, offering home sample collection without needing to visit a lab. Localities include Connaught Place, Chandni Chowk, Karol Bagh, Lajpat Nagar, South Extension, Greater Kailash, Hauz Khas, Saket, Vasant Kunj, Dwarka, Rohini, Pitampura, Janakpuri, Rajouri Garden, Mayur Vihar, Preet Vihar, Shahdara, Laxmi Nagar, Green Park, Safdarjung Enclave, Defence Colony, New Friends Colony, Kalkaji, Malviya Nagar, Nehru Place.

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    References

    1. Estradiol blood test [Internet]. UCSF Health.  Available from:  https://www.ucsfhealth.org/medical-tests/estradiol-blood-test
    2. Oestrogen blood test [Internet]. Health Direct.  Available from:  https://www.healthdirect.gov.au/oestrogen-blood-test
    3. Hariri L, Rehman A. Estradiol. [Updated 2023 Jun 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK549797/
    4. Blood Test: Estradiol [Internet]. The Nemours Foundation.  Available from:  https://kidshealth.org/en/parents/blood-test-estradiol.html