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    What is a Dengue NS1 Antigen ELISA Test?

    The Dengue NS1 Antigen ELISA test spots the non-structural protein 1 (NS1) of the dengue virus in a blood sample, with antigens being any foreign substances entering the body. This detection is feasible during the acute phase of dengue fever, which spans the first 7 days, facilitating early diagnosis and necessary medical treatment.

    Mosquito bites are the primary means of transmission for dengue fever, which is brought on by one of the four serotypes of the dengue virus from the Flavivirus family. When bitten by an infected mosquito, the virus enters the bloodstream and starts to multiply. This virus and the immune system's reaction cause the symptoms of dengue fever. The Dengue NS1 test can identify the virus in the blood during the first 7 days of symptom appearance. Research shows that NS1 antigen levels in the blood are linked to disease severity, with higher levels observed in severe cases. Therefore, the Dengue Antigen test is a critical diagnostic tool for dengue infections.

    For those in Delhi showing dengue symptoms, a Dengue Antigen test can be extremely helpful. Schedule a Dengue Antigen test in Delhi today to check your dengue status if you believe you have been exposed to the virus.

    Dengue NS1 Antigen ELISA Test Parameters

    Dengue is transmitted by Aedes mosquito bites. When an infected mosquito bites a person with dengue fever and then bites a healthy person, it spreads the infection. The dengue virus can negatively impact blood components that form clots and maintain the structure of blood vessels. Internal bleeding may result from this damage combined with immune system chemicals causing blood to leak from vessels. Therefore, it is important to get tested promptly if symptoms appear.

    The Dengue NS1 Antigen test focuses only on one parameter: the identification of the dengue NS1 protein, which is released into the bloodstream during infection. This test is performed on a blood sample using special antibodies to detect the NS1 antigen. Antibodies are proteins that the immune system produces in response to antigens such as NS1. The presence of NS1 in the blood confirms an acute dengue virus infection, but its absence does not rule out infection. Additional testing may be necessary to confirm the diagnosis.

    Dengue NS1 Antigen ELISA Test Preparation

    It is crucial to consider the following elements prior to having a Dengue Fever NS1 Antigen test:

    Prerequisites

    The Dengue NS1 test does not require fasting.

    Best Time to Get Tested

    The Dengue Antigen test can be administered at any time of day.

    Who Should Consider a Dengue NS1 ELISA Test

    The test is advised if you have been in a dengue-prone area and show symptoms such as high fever, rash, nausea, vomiting, muscle and joint pain, and pain behind the eyes.

    Cautions Before Taking Dengue NS1 ELISA Test

    There are no special cautions to observe before the Dengue NS1 test.

    Why Take a Dengue NS1 Antigen ELISA Test?

    You should take a Dengue NS1 test if you live in or have been to an area where dengue fever is common and have recently been showing symptoms of dengue. The symptoms of dengue fever usually arise within 4 to 10 days after a mosquito bite and continue for 3 to 7 days. Symptoms typically include a sudden fever reaching up to 104°F or above along with any of the following symptoms:

    • Rash

    • Nausea and vomiting

    • Severe pain behind the eyes

    • Headache

    • Muscle, bone, or joint pain

    If neglected, some individuals may develop a life-threatening worsening of symptoms called dengue haemorrhagic fever that causes nose bleeds, bleeding gums, abdominal pain, frequent vomiting, throwing up blood, blood in stools, and extreme tiredness. The risk of severe dengue underscores the need for early detection and treatment of this infection.

    Since the NS1 antigen is detectable in the blood during the acute phase of infection, the NS1 test is done in the first 7 days of experiencing symptoms. After the first week, the NS1 test may not be as sensitive in diagnosing dengue.

    The Dengue Antigen test thus helps doctors with early detection of dengue, confirming dengue infection, and ruling out other non-dengue illnesses that have similar symptoms.

    Dengue NS1 Antigen ELISA Test Results & Interpretation

    The below table explains the interpretation of the results of a Dengue NS1 ELISA test:

    NS1 ResultsIndex ValuesInterpretation
    Negative≤0.8Retest if NS1 antigen is not found. Further assessment is needed if symptoms persist.
    Equivocal0.8 to 1.1Should undergo testing using an alternative method.
    Positive≥1.1Indicates a dengue virus infection.

    It is important to note that interference may occur in some cases where the blood sample contains antibodies against test components. For example, when testing for dengue virus, the test might also detect antibodies from cross-reactivity with other Flaviviruses or other non-infectious conditions, potentially leading to false-positive results or misinterpretation of the test. Therefore, when interpreting test results, it's essential to consider the patient's clinical history to ensure an accurate diagnosis. In such cases, using both NS1 detection and IgM Antibody tests can enhance the accuracy of diagnosing dengue infection. It’s also important to note that the dengue NS1 ELISA is the preferred test within the initial 7 days of symptom onset. After 7-10 days, dengue fever IgG and IgM antibody tests are recommended.

    FAQs on Dengue NS1 Antigen ELISA Test in Delhi

    The Dengue NS1 Antigen ELISA test price is ₹600. This cost covers the fastest possible home sample collection, which can be completed in 60 minutes of confirming the test. Results are made available in 12 hours.

    The Dengue NS1 Antigen test helps diagnose dengue infection in the early stage, specifically within 7 days of the onset of symptoms.

    No, you do not need to fast before this test.

    Yes, home sample collection for the Dengue NS1 ELISA test is available with Orange Health Labs. An eMedic will arrive at your location to collect your sample within 60 minutes of test confirmation, depending on slot availability. You may also schedule the test at your chosen date and time.

    Booking any blood test or health checkup on our platform is easy with these steps:

    • Search for the Test : Locate the Dengue NS1 Antigen test in Delhi or at home and choose Orange Health’s page.

    • Book the Test : Select the desired test, review prerequisites, provide your address, and confirm the booking by choosing a suitable sample collection time slot.

    • Sample Collection : Our experienced eMedic will arrive at your home within the scheduled time slot for sample collection.

    • Lab Processing : The collected sample will be sent to our NABL accredited and ICMR approved labs for processing.

    • Get Your Results : Your reports will be delivered to you via email, WhatsApp, or our app within 12 hours of sample collection.

    Interpretation of Dengue NS1 ELISA test results includes:

    • Negative: Index values ≤0.8. Retesting is advised if NS1 antigen is not detected.

    • Equivocal: Index values between 0.8 and 1.1. It is recommended to perform further testing with a different method.

    • Positive: Index values ≥1.1, indicating a dengue virus infection.

    The Orange Health Labs eMedic arrive at your location within 60 minutes of test confirmation. The sample is usually taken in less than 5 minutes, and you will receive your results online in 12 hours.

    Testing frequency is determined by your doctor's recommendation, taking into account your symptoms, test outcomes, and any pre-existing conditions. Typically, this test is advised only once during the early phase of a dengue infection.

    The Dengue NS1 Antigen test's single parameter is to identify the NS1 protein, which appears in the blood during the infection.

    The Dengue NS1, IgM, and IgG tests each target different parts of the virus and the immune response to a dengue infection:

    • NS1 test: Detects the virus's NS1 protein, present in the blood during the early stages of infection, detectable from days 1 to 7 of symptom onset.

    • IgM test: Detects IgM antibodies, which appear from day 3 to day 5 of infection and persist for 2 to 3 months.

    • IgG test: Detects IgG antibodies, which typically appear by day 14 and persist for life.

    The antigen and antibody test results are used together to confirm a current dengue virus infection.

    Yes, in some cases, the NS1 antigen may be detectable in the blood for a few extra days following the acute phase of infection.

    A positive NS1 test result confirms dengue infection but does not specify the virus serotype. For serotype identification, nucleic acid amplification tests (NAAT) such as real-time reverse transcriptase-polymerase chain reaction (RT-PCR) are required to detect the dengue virus's genetic material.

    Even if your NS1 test result is negative, it does not mean you are free from dengue infection if you have been exposed to the virus. Your doctor may advise further testing, such as NAAT (RT-PCR) or an IgM antibody test, to ensure an accurate diagnosis.

    Orange Health provides the quickest Dengue Fever NS1 Antigen test services in Delhi without the need to visit a physical lab. Localities include but are not limited to Connaught Place, Chandni Chowk, Karol Bagh, Lajpat Nagar, South Extension, Greater Kailash, Hauz Khas, Saket, Vasant Kunj, Dwarka, Rohini, Pitampura, Janakpuri, Rajouri Garden, Mayur Vihar, Preet Vihar, Shahdara, Laxmi Nagar, Green Park, Safdarjung Enclave, Defence Colony, New Friends Colony, Kalkaji, Malviya Nagar, Nehru Place.

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