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    What is a Dengue profile (ELISA) Test?

    A Dengue Blood test is used to check for the presence of the dengue virus in a blood sample. Known as the Dengue Fever Profile (ELISA) test, this test is useful if you exhibit symptoms of dengue fever or reside in or have recently visited areas where dengue cases are prevalent. The test employs the ELISA method to diagnose the infection, involving a combination of several tests to provide a comprehensive assessment of the infection. These tests include:

    • Dengue NS1 Test

    • Dengue IgG Test

    • Dengue IgM Test

    For those seeking a Dengue test in Delhi, Comprehensive Dengue test packages are available at diagnostic facilities such as Orange Health Labs. These packages incorporate various blood tests that aid in diagnosing dengue infection. Prompt diagnosis is crucial for effective disease management and the prevention of severe complications.

    Dengue profile (ELISA) Test Parameters

    The dengue virus can present with a range of symptoms, many of which are nonspecific. Prompt identification of dengue through laboratory testing is essential as dengue, if not diagnosed on time, can quickly worsen to a severe stage. Dengue tests evaluate various parameters to diagnose and monitor the infection, including:

    All these tests, including the NS1 and IgG/IgM tests, are performed using the ELISA method (Enzyme-Linked Immunosorbent Assay), which detects antibodies or antigens through a quantifiable enzymatic reaction.

    NS1 Antigen

    IgG and IgM Antibodies

    Dengue profile (ELISA) Test Preparation

    The Dengue Test does not require major preparations; however, here are some things you should know:

    Prerequisites

    The Dengue Blood test does not require fasting.

    Best Time to Get Tested

    It is advisable to undergo testing promptly upon the onset of symptoms, typically within the first 5 days of fever. NS1 Dengue ELISA tests are most effective within the initial 7 days of symptoms. IgG and IgM tests may be more appropriate in later stages, around 7-10 days after symptom onset.

    Who Should Get the Test

    If an individual has dengue symptoms such as high fever, rash, joint and muscle pain, severe headache, bleeding (e.g., nose or gums), or pain behind the eyes, undergoing a Dengue test is recommended.

    Cautions Before Taking the Test

    No specific precautions need to be taken before the test.

    Why Take a Dengue profile (ELISA) Test?

    Getting a Dengue Blood test done is essential in individuals with dengue symptoms for the following reasons:

    Recent Exposure/ Travel History: If you have recently travelled to an area with a high prevalence of dengue cases, testing is recommended for early diagnosis.

    Early Detection : Dengue tests play a pivotal role in detecting the disease early, which is crucial for initiating timely treatment and effectively managing symptoms.

    Accurate Diagnosis of Symptoms: The Dengue test helps detect active infection in individuals experiencing symptoms such as high fever, rash, joint and muscle pain, severe headache, bleeding, or pain behind the eyes. The test provides a precise diagnosis by distinguishing dengue from other viral infections.

    Prevention of Serious Complications: Dengue tests are also important to identify dengue and, thereby, prevent its progress to severe complications associated with dengue such as haemorrhagic fever and dengue shock syndrome.

    Manage Infectious Outbreaks: Identifying and reporting cases of dengue is essential for public health efforts, as it helps in monitoring outbreaks and implementing necessary control measures to prevent further spread of the disease.

    For those unable to visit a testing centre, getting a Dengue test at home through various laboratories that offer home-based testing can be a convenient alternative.

    Dengue profile (ELISA) Test Results & Interpretation

    The following table will help interpret the results of the Dengue test:

    Antibody or AntigenResult (Index)Interpretation
    Dengue NS1 AntigenNegative ≤0.8 Equivocal 0.8 to ≤1.1 Positive ≥1.1For negative results, re-testing may be necessary. For an equivocal result, an alternative testing method should be used. A positive result indicates a primary* Dengue virus infection.
    Dengue IgG AntibodyNegative <0.8 Equivocal 0.8 to <1.1 Positive ≥1.1For negative results, re-testing may be necessary. For an equivocal result, an alternative testing method should be used. A positive result indicates either a primary or secondary** Dengue virus infection.
    Dengue IgM AntibodyNegative <0.8 Equivocal 0.8 to <1.1 Positive ≥1.1For negative results, re-testing may be necessary. For an equivocal result, an alternative testing method should be used. A positive result indicates a primary Dengue virus infection.

    *A primary dengue infection indicates dengue infection for the first time in an individual’s life. **Secondary dengue infection indicates that the patient has had dengue infection in the past and may have dengue again.

    Identification of the NS1 antigen on the test indicates an active dengue infection, while the presence of IgM antibodies suggests recent exposure to the virus. The presence of IgG antibodies indicates a history of dengue infection. Thus these tests assist doctors in reaching an accurate diagnosis and devising effective treatment plans and health management strategies to ensure timely recovery.

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