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    Anti Mitochondrial antibody (IFA)2399210012% off
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    What is Anti Mitochondrial antibody (IFA) Test?

    The Anti-Mitochondrial Antibody (AMA) test detects antimitochondrial antibodies in the blood. 1 AMA is a highly specific and sensitive marker for primary biliary cholangitis/cirrhosis (PBC), a chronic autoimmune liver disease. These antibodies are present in over 95% of individuals with PBC.

    PBC is a disorder that primarily affects middle-aged individuals and is often associated with other autoimmune conditions such as Sjögren’s syndrome. The disease leads to progressive scarring of the liver due to the immune system attacking bile ducts, impairing the liver’s ability to function properly.

    The IFA (Immunofluorescence Assay) method used in this test helps accurately identify AMA, particularly M2 antibodies strongly linked to PBC. Early detection with the AMA test is crucial, as timely intervention can slow disease progression, reduce liver damage, and delay liver failure.

    This test is essential for diagnosing autoimmune liver diseases and monitoring liver health. 3 It also helps in distinguishing PBC from other hepatobiliary disorders. If you have persistent liver function abnormalities or symptoms suggestive of PBC, scheduling an Anti-Mitochondrial Antibody test at home may help in further evaluation.

    Anti Mitochondrial antibody (IFA) Test Parameters

    The Anti-Mitochondrial Antibody test measures the levels of antimitochondrial antibodies in the blood.

    Anti-mitochondrial antibodies are antibodies that are formed against the mitochondria, the energy-producing structures located within the cells. These antibodies target mitochondria, leading to liver damage over time. The presence of AMA in blood has been linked to autoimmune liver conditions like PBC. In addition to PBC, antimitochondrial antibodies may also be found in a small percentage of individuals with autoimmune hepatitis and other liver disorders. AMAs can appear in the bloodstream years before symptoms or significant liver function abnormalities develop. Therefore, the detection of AMA can help in the early detection of autoimmune liver damage.

    Anti Mitochondrial antibody (IFA) Test Preparation

    Preparing for an Anti-Mitochondrial Antibody (IFA) test at home is convenient with this information:

    • Prerequisites

    Fasting is generally not required for the Anti-Mitochondrial Antibody (IFA) test. However, it is advisable to consult your doctor for any specific preparation instructions.

    • Best Time to Get Tested

    The AMA test can be conducted at any convenient time ensuring ease and flexibility.

    • Who Should Get an Anti-Mitochondrial Antibody (IFA) Test?

    The test is recommended for individuals experiencing symptoms of PBC or other autoimmune liver diseases. It may also be advised for those with persistent abnormal liver function tests, unexplained jaundice, or chronic fatigue associated with liver disorders.

    • Cautions Before Taking an Anti-Mitochondrial Antibody (IFA) Test

    Inform your doctor about any ongoing medications, recent infections, or autoimmune conditions, as these factors may influence test results.

    Why Take the Anti Mitochondrial antibody (IFA) Test?

    The Anti-Mitochondrial Antibody test is essential as it can:

    Diagnose PBC: The AMA test is primarily used to diagnose a chronic autoimmune liver condition, primary biliary cholangitis.

    Differentiate between various liver disorders: The test helps differentiate PBC from other liver conditions, such as viral hepatitis, alcoholic cirrhosis, and bile duct blockages.

    A doctor may recommend this test upon presentation of the following symptoms of PBC-associated liver damage:

    • Persistent fatigue

    • Itching (pruritus)

    • Abdominal pain or discomfort

    • Nausea and poor appetite

    • Bone, muscle, and joint pain

    • Unexplained weight loss

    • Yellowing of the skin and eyes (jaundice)

    • Dry eyes and mouth (linked to Sjögren’s syndrome)

    • Swelling in the ankles or abdomen due to fluid buildup

    • Dark urine

    FAQs on Anti Mitochondrial antibody (IFA) Test in Bangalore

    The cost of the Anti-Mitochondrial Antibody (IFA) test in Bangalore is ₹2100. This includes home sample collection within 60 minutes, with test results available in 97 hours after sample collection.

    Yes, Orange Health Labs offers home sample collection for the Anti-Mitochondrial Antibody (IFA) test. A trained eMedic will visit your location within 60 minutes of booking to collect your sample.

    The Anti-Mitochondrial Antibody test is primarily used to detect primary biliary cholangitis (PBC), a chronic autoimmune liver disease. It helps differentiate PBC from other liver conditions, including viral hepatitis, alcoholic cirrhosis, and bile duct blockages.

    Fasting is not required before the Anti-Mitochondrial Antibody test. However, it is best to follow any specific instructions given by your doctor.

    Booking the Anti-Mitochondrial Antibody (IFA) test with Orange Health Labs can be done as follows:

    • Find the Test: Search for the "Anti-Mitochondrial Antibody (IFA) test" on the Orange Health Labs platform.

    • Confirm Your Appointment: Enter your details, select your location, and schedule a suitable time for sample collection.

    • Sample Collection: A well-trained eMedic will collect your sample from your home or office.

    • Laboratory Analysis: The sample is tested at an NABL-accredited, ICMR-approved laboratory.

    • Receive Results: The test report will be delivered via email or WhatsApp within 97 hours.

    The normal levels for the Antimicrobial Antibody Test are as follows:

    • Negative: ≤20.0 units

    • Equivocal: 20.1-24.9 units

    • Positive: ≥25.0 units.

    Test results for the Anti-Mitochondrial Antibody test are typically available within 97 hours after sample collection.

    The frequency of this test depends on your doctor’s recommendations. It may be performed periodically for patients diagnosed with PBC or other autoimmune liver diseases to monitor disease progression and response to treatment.

    The AMA test specifically detects anti-mitochondrial antibodies in the blood, which are markers of autoimmune liver diseases, particularly PBC.

    Orange Health Labs offers home sample collection for the Anti-Mitochondrial Antibody (IFA) test across multiple localities in Bangalore, including but not limited to Adugodi, Banashankari, Bannerghatta, Basavanagudi, Bellandur, BTM Layout, Chamrajpet, Cottonpet, CV Raman Nagar, Frazer Town, Giri Nagar, Hebbal, Domlur, Electronic City, Hennur, Hosur, HSR Layout, Jakkur, Jalahalli, Jaya Nagar, Kadugodi, Kammanahalli, Kengeri, Koramangala, Mahalakshmi Layout, Madiwala, Magadi Road, Malleshwaram, Marathahalli, Mathikere, Mysore Road, Nagarbhavi, Nandhini Layout, Old Airport Road, Peenya, RT Nagar, Rajaji Nagar, Rajarajeshwari Nagar, Sadashivnagar, Sahakara Nagar, Sanjay Nagar, Sarjapur, Seshadripuram, Shanthi Nagar, Shivaji Nagar, Sri Nagar, Tyagarajnagar, Uttarahalli, Vasanth Nagar, Vidyaranyapura, Vijaya Nagar, Whitefield, Yelahanka, Yeshwantpur. You can conveniently book the test and have your sample collected from the comfort of your home or office.

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    References

    1. Antimitochondrial Antibody and Antimitochondrial M2 Antibody - Health Encyclopedia - University of Rochester Medical Center.  Available from:  https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=167&contentid=antimitochondrial_antibody_m2
    2. Anti-mitochondrial antibody (AMA) [Internet]. South Tees Hospitals NHS Foundation Trust.  Available from:  https://www.southtees.nhs.uk/services/pathology/tests/anti-mitochondrial-antibody-ama/
    3. Antimitochondrial antibody: MedlinePlus Medical Encyclopedia [Internet].  Available from:  https://medlineplus.gov/ency/article/003529.htm
    4. Antimitochondrial antibody Information | Mount Sinai - New York.  Available from:  https://www.mountsinai.org/health-library/tests/antimitochondrial-antibody
    5. AMA: Mitochondrial Ab, McLendon Clinical Laboratories | UNC Medical Center, Hospitals – Chapel Hill, NC.  Available from:  https://www.uncmedicalcenter.org/mclendon-clinical-laboratories/available-tests/ama-mitochondrial-ab/