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    What is a Pre-Chemotherapy Blood Checkup ?

    A Pre-Chemotherapy Blood Checkup is a series of important tests conducted before initiating chemotherapy. These tests confirm that your body is well-prepared to handle the treatment and its effects, as chemotherapy can influence several critical bodily functions.

    The tests cover a range of parameters, including blood, liver, kidney, and clotting functions. A complete blood count is performed to measure red blood cells (RBCs), white blood cells (WBCs), and platelets. This is crucial because chemotherapy can lower these counts by affecting bone marrow production.

    Liver and kidney function tests are also carried out to evaluate how well these organs can manage and excrete chemotherapy drugs. Specific tests such as SGOT, SGPT, bilirubin, kidney function assessments, and electrolytes are included to ensure your organs are functioning optimally.

    The evaluation also includes blood sugar and clotting tests (like prothrombin time) to provide a broader health perspective. By undergoing this checkup, your doctor can adapt your chemotherapy regimen to your specific health needs, ensuring safety and effective treatment.

    Pre-Chemotherapy Blood Checkup Parameters

    Liver Function Test (LFT)

    Liver function is also called as liver profile or liver panel that measures different types of enzymes, proteins and other by products that are made by the liver. These tests analyses the levels of overall health of the liver. The liver performing its normal functions of producing protein and clearing bilirubin, a blood waste product.
    The liver panel test consists of:
    • Aspartate aminotransferase (AST): AST is an enzyme in your liver. High blood levels could be a sign of damage or disease.
    • Alanine aminotransferase (ALT): ALT is another enzyme that helps break down proteins and is found mainly in your liver. High levels in your blood could mean you have liver damage.
    • Alkaline phosphatase (ALP): ALP is an enzyme in your liver, bile ducts, and bones. You might have high values if you have liver damage or disease, and a blocked bile duct, or bone disease.
    • Bilirubin Total/Direct/ Indirect: Your body makes bilirubin when it breaks down red blood cells. Usually, your liver cleans up the bilirubin in your body. If you have high levels of a problem called jaundice, you may have liver damage.
    • Albumin: Albumin is a protein made by the liver that prevents the fluid from leaking out of the bloodstream.
    • Gamma-glutamyl transferase (GGT): High levels of the GGT enzyme could point to liver or bile duct damage.
    • Total protein: This analyses the sum of two kinds of protein in the blood known as albumin and globulin. The test may analyse the relative levels of albumin and globulin, which is reported as the A/G ratio.
    • Globulins: Globulins are a class of proteins in the blood.

    • Alkaline Phosphatase

    • SGOT / AST - Aspartate AminoTransferase

    • Alanine AminoTransferase/ ALT (SGPT)

    • Gamma-Glutamyl Transferase (GGT)

    • Total Bilirubin

    • Direct Bilirubin

    • Indirect Bilirubin

    • Total protein

    • ALBUMIN

    • Globulin

    • A:G ratio

    • SGOT/SGPT ratio

    Prothrombin Time (PT/INR)

    Blood clotting, or coagulation, is a necessary process which prevents a person from losing too much of blood if they are injured. However, sometimes clots formation can be dangerous, causing a serious problems like deep vein thrombosis (DVT) or pulmonary (lung) embolism. By evaluating the time, it takes your blood to clot via different methods, the PT tests help detect if you have a bleeding or clotting disorder. As per a pre-surgical test, the PT with INR test is performed that helps a doctor evaluate the likelihood of excessive bleeding or clotting to determine risks during or after surgery. This test is also clinically used to monitor individuals on a Warfarin (Coumadin®) anticoagulant (blood-thinner) therapy.

    Blood Sugar

    A Random blood sugar (RBS) test is one method for analysing the level of glucose or sugar circulating in the blood. This test can be done at any point in time. It is to check how well the blood glucose is been maintained.

    Kidney Function Test with Electrolytes (KFT / RFT)

    The Kidney/Renal (KFT/RFT) panel, also known as a kidney profile or kidney function test (KFT), is a group of tests that help in determining the health of the kidneys by evaluating various parameters, like proteins, electrolytes, minerals, and blood glucose.
    The most common components tested in most renal panels include:
    • Blood Urea/Blood Urea Nitrogen (BUN): The blood urea nitrogen test is derived from the blood urea. Sometimes it is also called urea. Blood urea is a waste product of protein activity. Like creatinine, it is removed from the blood by the kidneys and cleared from the body in the form of urine.
    • Creatinine: Creatinine is the by-product that is consistently formed as a result of normal muscle activity. The kidney removes creatinine from the blood so that it can be carried out of the body in the form of urine.
    • Calcium: Calcium is a mineral that is very vital for the bones, muscles, cardiovascular system, and nervous system. An excess of calcium makes the kidneys work harder to filter it.
    • Phosphorus: Phosphorus is a very essential mineral for the bones, teeth, nervous system, and muscles. Phosphorus is also needed to help balance and use other vitamins and minerals, including vitamin D, iodine, magnesium, and zinc. This phosphorus comes primarily from the foods and drinks that we consume.
    • Uric Acid: Uric Acid test is to analyse a nitrogenous compound that is produced by the metabolic breakdown of purine. Uric acid is also formed from the metabolic breakdown of the same types of food, like red meat, seafood, beans, etc.
    • Sodium: Sodium is an electrolyte that comes from the diet, and the levels of sodium (Na) in the body are mainly controlled by the kidneys.
    • Potassium: Potassium plays a key role in a number of bodily processes, including nerve transmission, heart contractility, cellular transport, and normal kidney function. Potassium is a type of electrolyte. Electrolytes are minerals that enable the acid-base balance, healthy fluid levels, and proper functioning of muscles and nerves. Potassium comes from the diet and is found throughout the body.
    • Chloride: Chloride is an electrolyte that works in conjunction with other electrolytes to carry out several functions, including preserving a healthy balance of fluids.

    • Urea

    • Blood Urea Nitrogen (BUN)

    • Uric acid

    • Phosphorus

    • Calcium

    • Creatinine

    • eGFR

    • Sodium

    • Potassium

    • Chloride

    • BUN Creatinine ratio

    Complete Blood Count (CBC) with ESR

    A Complete Blood Count (CBC) is a blood test used to examine your overall health and detect a wide range of disorders, including anemia, infection, and leukemia. Complete blood count test (CBC) measures several components of your blood including:
    • Red blood cells which helps to carry oxygen
    • White blood cells which helps to fight infection
    • Haemoglobin which carries oxygen in the red blood cells
    • Hematocrit (PCV) measures the proportion of red blood cells to the fluid component, or plasma, in your blood
    • Platelets which help with blood clotting
    An abnormal cell count may indicate that you have a medical condition that calls for further evaluation.

    • Red Blood Cell Count (RBC Count)

    • HEMATOCRIT

    • Haemoglobin (Hb)

    • Total WBC Count (TC)

    • MCV

    • MCH

    • MCHC

    • RDW

    • Absolute Neutrophil Count (ANC)

    • Absolute Lymphocyte Count (ALC)

    • Absolute Eosinophil Count (AEC)

    • Absolute monocyte count

    • absolute basophil count

    • platelets

    • neutrophil

    • Monocyte

    • Eosinophils

    • Basophils

    • mentzer index

    • Sehgal Index

    • platelet hematocrit

    • Erythrocyte Sedimentation Rate (ESR)

    • MPV

    • Neutrophil lymphocyte ratio

    • lymphocyte count

    Pre-Chemotherapy Blood Checkup Preparation

    Consider the following points when scheduling a Pre-Chemotherapy Blood Checkup at home in Mumbai:

    Prerequisites

    There is no need to fast before taking this checkup.

    Best Time to Get Tested

    A Pre-Chemotherapy Blood Checkup in Mumbai can be done at any time during the day.

    Who Should Get a Pre-Chemotherapy Blood Checkup

    This test is essential for individuals starting chemotherapy. It checks blood cells and assesses liver and kidney function, ensuring readiness for treatment and facilitating personalised care to reduce risks.

    Cautions Before Taking a Pre-Chemotherapy Blood Checkup

    No special preparations are required for this test when done at home.

    Why Take the Pre-Chemotherapy Blood Checkup Checkup?

    A Pre-Chemotherapy Blood Checkup is essential to ensure your body is well-prepared for chemotherapy. Blood tests performed before treatment examine red blood cells (RBCs), white blood cells (WBCs), and platelets. Chemotherapy medications often impact bone marrow, leading to lower blood cell counts. Low RBC levels may require a transfusion, and reduced WBC or platelet counts could make treatment hazardous.

    These tests also assess liver and kidney function, as these organs are responsible for processing chemotherapy drugs. Liver health is evaluated through tests like SGOT, SGPT, and bilirubin, while kidney function is monitored via urea, creatinine, and electrolyte levels. Ensuring these organs are functioning properly is critical for safely metabolising the medications.

    Blood sugar and clotting time tests are also included, giving your doctor a complete picture of your health.

    By undergoing this checkup, potential problems can be addressed early. Test results provide a baseline for your health, allowing doctors to monitor any changes during your treatment. If irregularities are found, treatment may be postponed or adapted to reduce complications. Regular testing helps tailor chemotherapy to your unique health profile, ensuring both safety and effectiveness.

    FAQs on Pre-Chemotherapy Blood Checkup in Mumbai

    The Pre-Chemotherapy Blood Checkup costs ₹ 1999. This includes the quickest home sample collection service, completed within 60 minutes of booking.

    Yes, Orange Health Labs provides the option of home sample collection for this checkup, ensuring convenience. An eMedic will arrive at your location within 60 minutes of booking (depending on availability) or at your selected time.

    The checkup is designed to evaluate your general health, including liver and kidney function, blood cell levels, and your suitability for chemotherapy.

    Fasting is not needed for this blood checkup when done at home.

    To book the test:

    • Search for the Test: Find the Pre-Chemotherapy Blood Checkup and select the Orange Health option.

    • Test Booking: Review the details, confirm the prerequisites, add your address, and finalise your appointment by selecting a convenient time slot.

    • Sample Collection: Our trained eMedic will collect your sample during your chosen time slot.

    • Laboratory Processing: The sample will be analysed in our NABL-accredited, ICMR-approved lab.

    • Receive Results: Reports will be delivered via email or WhatsApp within 3 hours, with access available through our app.

    Normal levels vary across the included tests. For detailed ranges, refer to our website.

    The sample collection process is quick, and results are typically available within 3 hours of collection.

    Your doctor will recommend the frequency based on your health and treatment needs.

    This checkup consists of five tests: CBC, Liver Function Tests, Kidney Function Tests, Blood Sugar, and Prothrombin Time, covering 50 parameters.

    Orange Health offers the fastest Pre-Chemotherapy Blood Checkup services in Mumbai, conducted conveniently at your home without needing a physical laboratory visit. Localities served include but are not restricted to Colaba, Nariman Point, Marine Drive, Malabar Hill, Churchgate, Worli, Dadar, Parel, Byculla, Bandra, Andheri, Juhu, Ghatkopar, Powai, Chembur, Vashi, Belapur, Santacruz, Khar, Versova, Lokhandwala, Goregaon, Borivali, Kandivali, Mulund, Bhandup, Kurla.

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    References

    1. Chambers P, Wei L, Forster MD, Kipps E, Wong ICK, Jani Y. Evidence to guide the optimal timing for pre‐chemotherapy blood tests for early breast, colorectal cancer and diffuse large B‐cell lymphoma. Cancer Medicine. 2021 Sep 28  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC8607255/
    2. Cancer Research UK. Chemotherapy tests | Cancer in general | Cancer Research UK [Internet].  Available from:  https://www.cancerresearchuk.org/about-cancer/treatment/chemotherapy/planning/chemotherapy-tests
    3. Warr J, Hird AE, DeAngelis C, Giotis A, Ko YJ. Baseline blood work before initiation of chemotherapy: what is safe in the real world? J Oncol Pract. 2013 Sep.  Available from:  https://ascopubs.org/doi/abs/10.1200/JOP.2012.000719