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    What is a Pre-Chemotherapy Blood Checkup ?

    A Pre-Chemotherapy Blood Checkup comprises essential blood tests carried out before starting chemotherapy. These tests assess whether your body is ready to tolerate the treatment and its potential impact, as chemotherapy can significantly affect several body systems.

    The checkup examines critical health aspects such as blood composition, liver function, kidney function, and clotting capacity. A full blood count evaluates red blood cells (RBCs), white blood cells (WBCs), and platelets, which are often reduced during chemotherapy due to its impact on bone marrow activity.

    Liver and kidney assessments are included to gauge their ability to metabolise and eliminate chemotherapy drugs. Tests like SGOT, SGPT, bilirubin, kidney function tests, and electrolyte levels provide a comprehensive understanding of organ health.

    Additional tests, including blood sugar levels and clotting time (prothrombin time), help create a detailed health profile. Completing this checkup allows your doctor to customise the chemotherapy plan, reducing complications and enhancing treatment effectiveness.

    Pre-Chemotherapy Blood Checkup Parameters

    Liver Function Test (LFT)

    Liver function is also called as liver profile or liver panel that measures different types of enzymes, proteins and other by products that are made by the liver. These tests analyses the levels of overall health of the liver. The liver performing its normal functions of producing protein and clearing bilirubin, a blood waste product.
    The liver panel test consists of:
    • Aspartate aminotransferase (AST): AST is an enzyme in your liver. High blood levels could be a sign of damage or disease.
    • Alanine aminotransferase (ALT): ALT is another enzyme that helps break down proteins and is found mainly in your liver. High levels in your blood could mean you have liver damage.
    • Alkaline phosphatase (ALP): ALP is an enzyme in your liver, bile ducts, and bones. You might have high values if you have liver damage or disease, and a blocked bile duct, or bone disease.
    • Bilirubin Total/Direct/ Indirect: Your body makes bilirubin when it breaks down red blood cells. Usually, your liver cleans up the bilirubin in your body. If you have high levels of a problem called jaundice, you may have liver damage.
    • Albumin: Albumin is a protein made by the liver that prevents the fluid from leaking out of the bloodstream.
    • Gamma-glutamyl transferase (GGT): High levels of the GGT enzyme could point to liver or bile duct damage.
    • Total protein: This analyses the sum of two kinds of protein in the blood known as albumin and globulin. The test may analyse the relative levels of albumin and globulin, which is reported as the A/G ratio.
    • Globulins: Globulins are a class of proteins in the blood.

    • Alkaline Phosphatase

    • SGOT / AST - Aspartate AminoTransferase

    • Alanine AminoTransferase/ ALT (SGPT)

    • Gamma-Glutamyl Transferase (GGT)

    • Total Bilirubin

    • Direct Bilirubin

    • Indirect Bilirubin

    • Total protein

    • ALBUMIN

    • Globulin

    • A:G ratio

    • SGOT/SGPT ratio

    Prothrombin Time (PT/INR)

    Blood clotting, or coagulation, is a necessary process which prevents a person from losing too much of blood if they are injured. However, sometimes clots formation can be dangerous, causing a serious problems like deep vein thrombosis (DVT) or pulmonary (lung) embolism. By evaluating the time, it takes your blood to clot via different methods, the PT tests help detect if you have a bleeding or clotting disorder. As per a pre-surgical test, the PT with INR test is performed that helps a doctor evaluate the likelihood of excessive bleeding or clotting to determine risks during or after surgery. This test is also clinically used to monitor individuals on a Warfarin (Coumadin®) anticoagulant (blood-thinner) therapy.

    Blood Sugar

    A Random blood sugar (RBS) test is one method for analysing the level of glucose or sugar circulating in the blood. This test can be done at any point in time. It is to check how well the blood glucose is been maintained.

    Kidney Function Test with Electrolytes (KFT / RFT)

    The Kidney/Renal (KFT/RFT) panel, also known as a kidney profile or kidney function test (KFT), is a group of tests that help in determining the health of the kidneys by evaluating various parameters, like proteins, electrolytes, minerals, and blood glucose.
    The most common components tested in most renal panels include:
    • Blood Urea/Blood Urea Nitrogen (BUN): The blood urea nitrogen test is derived from the blood urea. Sometimes it is also called urea. Blood urea is a waste product of protein activity. Like creatinine, it is removed from the blood by the kidneys and cleared from the body in the form of urine.
    • Creatinine: Creatinine is the by-product that is consistently formed as a result of normal muscle activity. The kidney removes creatinine from the blood so that it can be carried out of the body in the form of urine.
    • Calcium: Calcium is a mineral that is very vital for the bones, muscles, cardiovascular system, and nervous system. An excess of calcium makes the kidneys work harder to filter it.
    • Phosphorus: Phosphorus is a very essential mineral for the bones, teeth, nervous system, and muscles. Phosphorus is also needed to help balance and use other vitamins and minerals, including vitamin D, iodine, magnesium, and zinc. This phosphorus comes primarily from the foods and drinks that we consume.
    • Uric Acid: Uric Acid test is to analyse a nitrogenous compound that is produced by the metabolic breakdown of purine. Uric acid is also formed from the metabolic breakdown of the same types of food, like red meat, seafood, beans, etc.
    • Sodium: Sodium is an electrolyte that comes from the diet, and the levels of sodium (Na) in the body are mainly controlled by the kidneys.
    • Potassium: Potassium plays a key role in a number of bodily processes, including nerve transmission, heart contractility, cellular transport, and normal kidney function. Potassium is a type of electrolyte. Electrolytes are minerals that enable the acid-base balance, healthy fluid levels, and proper functioning of muscles and nerves. Potassium comes from the diet and is found throughout the body.
    • Chloride: Chloride is an electrolyte that works in conjunction with other electrolytes to carry out several functions, including preserving a healthy balance of fluids.

    • Urea

    • Blood Urea Nitrogen (BUN)

    • Uric acid

    • Phosphorus

    • Calcium

    • Creatinine

    • eGFR

    • Sodium

    • Potassium

    • Chloride

    • BUN Creatinine ratio

    Complete Blood Count (CBC) with ESR

    A Complete Blood Count (CBC) is a blood test used to examine your overall health and detect a wide range of disorders, including anemia, infection, and leukemia. Complete blood count test (CBC) measures several components of your blood including:
    • Red blood cells which helps to carry oxygen
    • White blood cells which helps to fight infection
    • Haemoglobin which carries oxygen in the red blood cells
    • Hematocrit (PCV) measures the proportion of red blood cells to the fluid component, or plasma, in your blood
    • Platelets which help with blood clotting
    An abnormal cell count may indicate that you have a medical condition that calls for further evaluation.

    • Red Blood Cell Count (RBC Count)

    • HEMATOCRIT

    • Haemoglobin (Hb)

    • Total WBC Count (TC)

    • MCV

    • MCH

    • MCHC

    • RDW

    • Absolute Neutrophil Count (ANC)

    • Absolute Lymphocyte Count (ALC)

    • Absolute Eosinophil Count (AEC)

    • Absolute monocyte count

    • absolute basophil count

    • platelets

    • neutrophil

    • Monocyte

    • Eosinophils

    • Basophils

    • mentzer index

    • Sehgal Index

    • platelet hematocrit

    • Erythrocyte Sedimentation Rate (ESR)

    • MPV

    • Neutrophil lymphocyte ratio

    • lymphocyte count

    Pre-Chemotherapy Blood Checkup Preparation

    Before scheduling a Pre-Chemotherapy Blood Checkup at home in Delhi, take note of these key considerations:

    Prerequisites

    Fasting is not necessary for this test.

    Best Time to Get Tested

    The Pre-Chemotherapy Blood Checkup in Delhi can be conducted at any time of day.

    Who Should Get a Pre-Chemotherapy Blood Checkup

    This test is vital for individuals beginning chemotherapy. It evaluates blood cells, along with liver and kidney function, to confirm readiness for treatment and support customised treatment planning.

    Cautions Before Taking a Pre-Chemotherapy Blood Checkup

    No special steps are needed to prepare for this checkup when done at home.

    Why Take the Pre-Chemotherapy Blood Checkup Checkup?

    A Pre-Chemotherapy Blood Checkup is a critical step to confirm that your body can handle chemotherapy. Blood tests check red blood cells (RBCs), white blood cells (WBCs), and platelets before treatment begins. Since chemotherapy can suppress bone marrow activity, it’s important to address low RBC counts with transfusions and avoid the risks associated with low WBC or platelet levels.

    The checkup also evaluates kidney and liver function, as these organs process and clear chemotherapy drugs. Liver function tests like SGOT, SGPT, and bilirubin help assess liver health, while kidney function is checked through urea, creatinine, and electrolyte levels. These tests ensure your organs can safely process the treatment.

    Additionally, blood sugar and clotting time tests are included to give your doctor a detailed health overview.

    By performing this checkup, any health issues can be identified and managed before treatment begins. These tests establish a baseline to track your health throughout chemotherapy. If abnormalities are detected, your doctor may adjust or delay treatment to minimise risks. Ongoing monitoring ensures a safe, personalised approach to chemotherapy.

    FAQs on Pre-Chemotherapy Blood Checkup in Delhi

    The Pre-Chemotherapy Blood Checkup is priced at ₹ 1999. This cost includes fast home sample collection within 60 minutes after booking.

    Yes, Orange Health Labs offers home sample collection for the Pre-Chemotherapy Blood Checkup. An eMedic will reach your doorstep within 60 minutes of booking, depending on slot availability, or at a time you choose.

    This checkup determines your overall health status by evaluating liver and kidney function, blood cell levels, and your readiness for chemotherapy.

    Fasting is not required for the Pre-Chemotherapy Blood Checkup done at home.

    To book the test, follow these steps:

    • Search for the Test: Look up the Pre-Chemotherapy Blood Checkup and select Orange Health Labs.

    • Test Booking: Review the test details, check any requirements, provide your address, and schedule the sample collection.

    • Sample Collection: Our skilled eMedic will visit your home at the scheduled time to collect your sample.

    • Laboratory Processing: The sample is analysed at our NABL-accredited and ICMR-approved laboratory.

    • Receive Results: Reports are delivered via email or WhatsApp within 21 hours and can also be viewed through our app.

    Normal ranges for the included tests may vary. You can find detailed information on our website.

    Sample collection takes only a few minutes, and reports are typically ready within 21 hours of collection.

    Your doctor will decide how frequently this checkup should be done, based on your individual health needs.

    The checkup includes five tests: CBC, Liver Function Tests, Kidney Function Tests, Blood Sugar, and Prothrombin Time, which collectively analyse 50 health parameters.

    Orange Health offers the fastest Pre-Chemotherapy Blood Checkup services in Delhi, conducted conveniently at your home without needing a physical laboratory visit. Localities served include but are not restricted to Connaught Place, Chandni Chowk, Karol Bagh, Lajpat Nagar, South Extension, Greater Kailash, Hauz Khas, Saket, Vasant Kunj, Dwarka, Rohini, Pitampura, Janakpuri, Rajouri Garden, Mayur Vihar, Preet Vihar, Shahdara, Laxmi Nagar, Green Park, Safdarjung Enclave, Defence Colony, New Friends Colony, Kalkaji, Malviya Nagar, Nehru Place.

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    References

    1. Chambers P, Wei L, Forster MD, Kipps E, Wong ICK, Jani Y. Evidence to guide the optimal timing for pre‐chemotherapy blood tests for early breast, colorectal cancer and diffuse large B‐cell lymphoma. Cancer Medicine. 2021 Sep 28  Available from:  https://pmc.ncbi.nlm.nih.gov/articles/PMC8607255/
    2. Cancer Research UK. Chemotherapy tests | Cancer in general | Cancer Research UK [Internet].  Available from:  https://www.cancerresearchuk.org/about-cancer/treatment/chemotherapy/planning/chemotherapy-tests
    3. Warr J, Hird AE, DeAngelis C, Giotis A, Ko YJ. Baseline blood work before initiation of chemotherapy: what is safe in the real world? J Oncol Pract. 2013 Sep.  Available from:  https://ascopubs.org/doi/abs/10.1200/JOP.2012.000719